These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
238 related articles for article (PubMed ID: 18818303)
1. Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Lee T; Schwandner R; Swaminath G; Weiszmann J; Cardozo M; Greenberg J; Jaeckel P; Ge H; Wang Y; Jiao X; Liu J; Kayser F; Tian H; Li Y Mol Pharmacol; 2008 Dec; 74(6):1599-609. PubMed ID: 18818303 [TBL] [Abstract][Full Text] [Related]
2. Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor. Hudson BD; Due-Hansen ME; Christiansen E; Hansen AM; Mackenzie AE; Murdoch H; Pandey SK; Ward RJ; Marquez R; Tikhonova IG; Ulven T; Milligan G J Biol Chem; 2013 Jun; 288(24):17296-312. PubMed ID: 23589301 [TBL] [Abstract][Full Text] [Related]
3. Mutational analysis of G-protein coupled receptor--FFA2. Swaminath G; Jaeckel P; Guo Q; Cardozo M; Weiszmann J; Lindberg R; Wang Y; Schwandner R; Li Y Biochem Biophys Res Commun; 2011 Feb; 405(1):122-7. PubMed ID: 21216233 [TBL] [Abstract][Full Text] [Related]
4. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. Schmidt J; Smith NJ; Christiansen E; Tikhonova IG; Grundmann M; Hudson BD; Ward RJ; Drewke C; Milligan G; Kostenis E; Ulven T J Biol Chem; 2011 Mar; 286(12):10628-40. PubMed ID: 21220428 [TBL] [Abstract][Full Text] [Related]
5. The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators. Wang Y; Jiao X; Kayser F; Liu J; Wang Z; Wanska M; Greenberg J; Weiszmann J; Ge H; Tian H; Wong S; Schwandner R; Lee T; Li Y Bioorg Med Chem Lett; 2010 Jan; 20(2):493-8. PubMed ID: 20005104 [TBL] [Abstract][Full Text] [Related]
6. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Milligan G; Stoddart LA; Smith NJ Br J Pharmacol; 2009 Sep; 158(1):146-53. PubMed ID: 19719777 [TBL] [Abstract][Full Text] [Related]
8. Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3. Hudson BD; Tikhonova IG; Pandey SK; Ulven T; Milligan G J Biol Chem; 2012 Nov; 287(49):41195-209. PubMed ID: 23066016 [TBL] [Abstract][Full Text] [Related]
9. A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias. Bolognini D; Moss CE; Nilsson K; Petersson AU; Donnelly I; Sergeev E; König GM; Kostenis E; Kurowska-Stolarska M; Miller A; Dekker N; Tobin AB; Milligan G J Biol Chem; 2016 Sep; 291(36):18915-31. PubMed ID: 27385588 [TBL] [Abstract][Full Text] [Related]
10. Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids. Stoddart LA; Smith NJ; Jenkins L; Brown AJ; Milligan G J Biol Chem; 2008 Nov; 283(47):32913-24. PubMed ID: 18801738 [TBL] [Abstract][Full Text] [Related]
11. Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling. Schofield ZV; Croker D; Robertson AAB; Massey NL; Donovan C; Tee E; Edwards D; Woodruff TM; Halai R; Hansbro PM; Cooper MA Sci Rep; 2018 Dec; 8(1):17819. PubMed ID: 30546040 [TBL] [Abstract][Full Text] [Related]
12. Ligands at the Free Fatty Acid Receptors 2/3 (GPR43/GPR41). Milligan G; Bolognini D; Sergeev E Handb Exp Pharmacol; 2017; 236():17-32. PubMed ID: 27757758 [TBL] [Abstract][Full Text] [Related]
13. Short-chain free fatty acid receptors FFA2/GPR43 and FFA3/GPR41 as new potential therapeutic targets. Ulven T Front Endocrinol (Lausanne); 2012; 3():111. PubMed ID: 23060857 [TBL] [Abstract][Full Text] [Related]
14. Synthesis, Activity, and Docking Study of Novel Phenylthiazole-Carboxamido Acid Derivatives as FFA2 Agonists. Ma L; Wang T; Shi M; Fu P; Pei H; Ye H Chem Biol Drug Des; 2016 Jul; 88(1):26-37. PubMed ID: 26808470 [TBL] [Abstract][Full Text] [Related]
15. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Smith NJ; Ward RJ; Stoddart LA; Hudson BD; Kostenis E; Ulven T; Morris JC; Tränkle C; Tikhonova IG; Adams DR; Milligan G Mol Pharmacol; 2011 Jul; 80(1):163-73. PubMed ID: 21498659 [TBL] [Abstract][Full Text] [Related]
16. FFA2 and FFA3 in Metabolic Regulation. Tang C; Offermanns S Handb Exp Pharmacol; 2017; 236():205-220. PubMed ID: 27757760 [TBL] [Abstract][Full Text] [Related]
18. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. Le Poul E; Loison C; Struyf S; Springael JY; Lannoy V; Decobecq ME; Brezillon S; Dupriez V; Vassart G; Van Damme J; Parmentier M; Detheux M J Biol Chem; 2003 Jul; 278(28):25481-9. PubMed ID: 12711604 [TBL] [Abstract][Full Text] [Related]
19. FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells. Lorza-Gil E; Kaiser G; Rexen Ulven E; König GM; Gerst F; Oquendo MB; Birkenfeld AL; Häring HU; Kostenis E; Ulven T; Ullrich S Sci Rep; 2020 Oct; 10(1):16497. PubMed ID: 33020504 [TBL] [Abstract][Full Text] [Related]
20. The Specificity and Broad Multitarget Properties of Ligands for the Free Fatty Acid Receptors FFA3/GPR41 and FFA2/GPR43 and the Related Hydroxycarboxylic Acid Receptor HCA2/GPR109A. Bisenieks E; Vigante B; Petrovska R; Turovska B; Muhamadejev R; Soloduns V; Velena A; Pajuste K; Saso L; Klovins J; Duburs G; Mandrika I Pharmaceuticals (Basel); 2021 Sep; 14(10):. PubMed ID: 34681211 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]