These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
384 related articles for article (PubMed ID: 18821748)
1. Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine. Long YQ; Xue T; Song YL; Liu ZL; Huang SX; Yu Q J Med Chem; 2008 Oct; 51(20):6371-80. PubMed ID: 18821748 [TBL] [Abstract][Full Text] [Related]
2. Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives. Song YL; Peach ML; Roller PP; Qiu S; Wang S; Long YQ J Med Chem; 2006 Mar; 49(5):1585-96. PubMed ID: 16509576 [TBL] [Abstract][Full Text] [Related]
3. Utilization of 3'-carboxy-containing tyrosine derivatives as a new class of phosphotyrosyl mimetics in the preparation of novel non-phosphorylated cyclic peptide inhibitors of the Grb2-SH2 domain. Song YL; Tan J; Luo XM; Long YQ Org Biomol Chem; 2006 Feb; 4(4):659-66. PubMed ID: 16467940 [TBL] [Abstract][Full Text] [Related]
4. Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics. Oishi S; Karki RG; Kang SU; Wang X; Worthy KM; Bindu LK; Nicklaus MC; Fisher RJ; Burke TR J Med Chem; 2005 Feb; 48(3):764-72. PubMed ID: 15689160 [TBL] [Abstract][Full Text] [Related]
5. Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain. Liu WQ; Vidal M; Gresh N; Roques BP; Garbay C J Med Chem; 1999 Sep; 42(18):3737-41. PubMed ID: 10479306 [TBL] [Abstract][Full Text] [Related]
6. Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems. Wei CQ; Gao Y; Lee K; Guo R; Li B; Zhang M; Yang D; Burke TR J Med Chem; 2003 Jan; 46(2):244-54. PubMed ID: 12519063 [TBL] [Abstract][Full Text] [Related]
7. Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs. Liu WQ; Vidal M; Olszowy C; Million E; Lenoir C; Dhôtel H; Garbay C J Med Chem; 2004 Feb; 47(5):1223-33. PubMed ID: 14971902 [TBL] [Abstract][Full Text] [Related]
8. Structural requirements for Tyr in the consensus sequence Y-E-N of a novel nonphosphorylated inhibitor to the Grb2-SH2 domain. Long YQ; Yao ZJ; Voigt JH; Lung FD; Luo JH; Burke TR; King CR; Yang D; Roller PP Biochem Biophys Res Commun; 1999 Nov; 264(3):902-8. PubMed ID: 10544028 [TBL] [Abstract][Full Text] [Related]
9. Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. Yao ZJ; King CR; Cao T; Kelley J; Milne GW; Voigt JH; Burke TR J Med Chem; 1999 Jan; 42(1):25-35. PubMed ID: 9888830 [TBL] [Abstract][Full Text] [Related]
10. Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides. Lee K; Zhang M; Liu H; Yang D; Burke TR J Med Chem; 2003 Jun; 46(13):2621-30. PubMed ID: 12801226 [TBL] [Abstract][Full Text] [Related]
13. Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide. Ogura K; Tsuchiya S; Terasawa H; Yuzawa S; Hatanaka H; Mandiyan V; Schlessinger J; Inagaki F J Mol Biol; 1999 Jun; 289(3):439-45. PubMed ID: 10356320 [TBL] [Abstract][Full Text] [Related]
14. Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin. Shi YH; Song YL; Lin DH; Tan J; Roller PP; Li Q; Long YQ; Song GQ Biochem Biophys Res Commun; 2005 May; 330(4):1254-61. PubMed ID: 15823578 [TBL] [Abstract][Full Text] [Related]
15. Structural basis for a non-phosphorus-containing cyclic peptide binding to Grb2-SH2 domain with high affinity. Li P; Zhang M; Peach ML; Zhang X; Liu H; Nicklaus M; Yang D; Roller PP Biochem Biophys Res Commun; 2003 Aug; 307(4):1038-44. PubMed ID: 12878216 [TBL] [Abstract][Full Text] [Related]
16. Design of tetrapeptide ligands as inhibitors of the Src SH2 domain. Nam NH; Pitts RL; Sun G; Sardari S; Tiemo A; Xie M; Yan B; Parang K Bioorg Med Chem; 2004 Feb; 12(4):779-87. PubMed ID: 14759738 [TBL] [Abstract][Full Text] [Related]
17. N-terminal carboxyl and tetrazole-containing amides as adjuvants to Grb2 SH2 domain ligand binding. Burke TR; Yao ZJ; Gao Y; Wu JX; Zhu X; Luo JH; Guo R; Yang D Bioorg Med Chem; 2001 Jun; 9(6):1439-45. PubMed ID: 11408162 [TBL] [Abstract][Full Text] [Related]
18. Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists. Li P; Zhang M; Peach ML; Liu H; Yang D; Roller PP Org Lett; 2003 Aug; 5(17):3095-8. PubMed ID: 12916990 [TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of 4-(alpha-hydroxymalonyl)phenylalanine as a new phosphotyrosyl mimetic and its use in growth factor receptor bound 2 src-homology 2 (Grb2 SH2) domain-binding peptides. Kang SU; Worthy KM; Bindu LK; Zhang M; Yang D; Fisher RJ; Burke TR J Med Chem; 2005 Aug; 48(16):5369-72. PubMed ID: 16078854 [TBL] [Abstract][Full Text] [Related]
20. Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain. Furet P; Gay B; Caravatti G; García-Echeverría C; Rahuel J; Schoepfer J; Fretz H J Med Chem; 1998 Aug; 41(18):3442-9. PubMed ID: 9719597 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]