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BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

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  • 1. On call. I reread your articles on congestive heart failure when I was diagnosed with the condition last month. My breathing is back to normal, and I feel well. My doctor has prescribed all the medications you recommended, but he disagreed with one. He said that since I'm taking Vasotec, I should stop my aspirin. Do you agree?
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  • 2. Ask the doctor. I have had heart failure since my heart attack a year ago. My physician initially prescribed lisinopril, an angiotensin-converting enzyme (ACE) inhibitor. Unfortunately, I was one of the unlucky people who got a cough with this drug that was so annoying I had to stop taking it. Now my doctor wants me to try a newer drug called valsartan. Is it likely to help me?
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  • 3. On call. I was recently diagnosed with high blood pressure. I reread your articles from December 2003 and January 2004 and found them very helpful. I was hoping that my doctor would prescribe a diuretic, but she said it would not be safe because I'm allergic to sulfa drugs. What do you think?
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  • 4. I'm a 57-year-old man with high blood pressure and high cholesterol. I had a hard time regulating my pressure until I went on Vasotec, which was great. But I developed a cough, so my doctor switched me to Cozaar. My cough stopped and my pressure seems okay, but I'd like to know what you think of the switch.
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  • 6. On call. I'm a 76-year-old man with an enlarged prostate. I've been taking Cardura and it's helped a lot, but my doctor stopped it because he said a study found the drug could cause heart failure. Now I'm getting up three or four times a night again. Is Cadura safe?
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  • 7. On call. My doctor prescribed Zestril for me because I have diabetes, even though my blood pressure has always been normal. I am 54, and my blood sugar came down to normal on pills. Do I really need another medicine?
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  • 8. By the way, doctor. My husband takes an aspirin every day to reduce his risk of another heart attack. I'm 60 and healthy. Is there any reason I shouldn't do the same to avoid a heart attack or stroke?
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  • 9. Ask the Doctor. I know that there have been a lot of studies showing that beta blockers help patients with congestive heart failure live longer. I have heart failure, and last year my doctor prescribed a beta blocker. In a few days, I became so short of breath that he had me stop taking it. I am upset that I can't use this important therapy. Is there any way I might be able to do so?
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  • 15. On call. In nearly every issue, you seem to discuss diet, exercise, or smoking - and in some issues you discuss all three. But my doctor has never asked me about my diet or exercise, though he does know that I hate smoking. Why don't I hear more about diet from my doctor?
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  • 16. A mechanistic interaction remains to be determined for elevated NTproBNP in heart failure patients receiving both an ACE inhibitor and aspirin.
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