122 related articles for article (PubMed ID: 18829312)
1. Novel 5-HT(1A/1B/1D) receptors antagonists with potent 5-HT reuptake inhibitory activity.
Serafinowska HT; Blaney FE; Lovell PJ; Merlo GG; Scott CM; Smith PW; Starr KR; Watson JM
Bioorg Med Chem Lett; 2008 Oct; 18(20):5581-5. PubMed ID: 18829312
[TBL] [Abstract][Full Text] [Related]
2. 6-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors.
Bromidge SM; Bertani B; Borriello M; Faedo S; Gordon LJ; Granci E; Hill M; Marshall HR; Stasi LP; Zucchelli V; Merlo G; Vesentini A; Watson JM; Zonzini L
Bioorg Med Chem Lett; 2008 Oct; 18(20):5653-6. PubMed ID: 18799312
[TBL] [Abstract][Full Text] [Related]
3. 3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity.
Atkinson PJ; Bromidge SM; Duxon MS; Gaster LM; Hadley MS; Hammond B; Johnson CN; Middlemiss DN; North SE; Price GW; Rami HK; Riley GJ; Scott CM; Shaw TE; Starr KR; Stemp G; Thewlis KM; Thomas DR; Thompson M; Vong AK; Watson JM
Bioorg Med Chem Lett; 2005 Feb; 15(3):737-41. PubMed ID: 15664848
[TBL] [Abstract][Full Text] [Related]
4. Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B.
Hughes ZA; Starr KR; Scott CM; Newson MJ; Sharp T; Watson JM; Hagan JJ; Dawson LA
Psychopharmacology (Berl); 2007 May; 192(1):121-33. PubMed ID: 17265079
[TBL] [Abstract][Full Text] [Related]
5. 8-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors--part II.
Bromidge SM; Bertani B; Borriello M; Bozzoli A; Faedo S; Gianotti M; Gordon LJ; Hill M; Zucchelli V; Watson JM; Zonzini L
Bioorg Med Chem Lett; 2009 Apr; 19(8):2338-42. PubMed ID: 19286377
[TBL] [Abstract][Full Text] [Related]
6. 5-HT reuptake inhibitors with 5-HT(1B/1D) antagonistic activity: a new approach toward efficient antidepressants.
Matzen L; van Amsterdam C; Rautenberg W; Greiner HE; Harting J; Seyfried CA; Böttcher H
J Med Chem; 2000 Mar; 43(6):1149-57. PubMed ID: 10737747
[TBL] [Abstract][Full Text] [Related]
7. SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
Scott C; Soffin EM; Hill M; Atkinson PJ; Langmead CJ; Wren PB; Faedo S; Gordon LJ; Price GW; Bromidge S; Johnson CN; Hagan JJ; Watson J
Eur J Pharmacol; 2006 Apr; 536(1-2):54-61. PubMed ID: 16571351
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and structure-activity relationship of novel lactam-fused chroman derivatives having dual affinity at the 5-HT(1A) receptor and the serotonin transporter.
Shen Z; Siva Ramamoorthy P; Hatzenbuhler NT; Evrard DA; Childers W; Harrison BL; Chlenov M; Hornby G; Smith DL; Sullivan KM; Schechter LE; Andree TH
Bioorg Med Chem Lett; 2010 Jan; 20(1):222-7. PubMed ID: 19932965
[TBL] [Abstract][Full Text] [Related]
9. Pyrrolidino-tetrahydroisoquinolines as potent dual H3 antagonist and serotonin transporter inhibitors.
Keith JM; Gomez LA; Wolin RL; Barbier AJ; Wilson SJ; Boggs JD; Mazur C; Fraser IC; Lord B; Aluisio L; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2007 May; 17(9):2603-7. PubMed ID: 17317177
[TBL] [Abstract][Full Text] [Related]
10. 3,4-Dihydro-2H-benzoxazinones as dual-acting 5-HT1A receptor antagonists and serotonin reuptake inhibitors.
Lovell PJ; Blaney FE; Goodacre CJ; Scott CM; Smith PW; Starr KR; Thewlis KM; Vong AK; Ward SE; Watson JM
Bioorg Med Chem Lett; 2007 Feb; 17(4):1033-6. PubMed ID: 17129726
[TBL] [Abstract][Full Text] [Related]
11. Effects of the potential antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone monomethanesulfonate] a combined sigma and 5-HT1A ligand: modulation of neuronal activity in the dorsal raphe nucleus.
Bermack JE; Haddjeri N; Debonnel G
J Pharmacol Exp Ther; 2004 Aug; 310(2):578-83. PubMed ID: 15044555
[TBL] [Abstract][Full Text] [Related]
12. Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitors.
Letavic MA; Keith JM; Ly KS; Barbier AJ; Boggs JD; Wilson SJ; Lord B; Lovenberg TW; Carruthers NI
Bioorg Med Chem Lett; 2007 May; 17(9):2566-9. PubMed ID: 17307358
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
Orús L; Pérez-Silanes S; Oficialdegui AM; Martínez-Esparza J; Del Castillo JC; Mourelle M; Langer T; Guccione S; Donzella G; Krovat EM; Poptodorov K; Lasheras B; Ballaz S; Hervías I; Tordera R; Del Río J; Monge A
J Med Chem; 2002 Sep; 45(19):4128-39. PubMed ID: 12213056
[TBL] [Abstract][Full Text] [Related]
14. Differential involvement of 5-HT(1A) and 5-HT(1B/1D) receptors in human interferon-alpha-induced immobility in the mouse forced swimming test.
Zhang H; Wang W; Jiang Z; Shang J; Zhang L
Arzneimittelforschung; 2010; 60(3):109-15. PubMed ID: 20422941
[TBL] [Abstract][Full Text] [Related]
15. N-Benzyl-N-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-amines as selective dual serotonin/noradrenaline reuptake inhibitors.
Fish PV; Fray MJ; Stobie A; Wakenhut F; Whitlock GA
Bioorg Med Chem Lett; 2007 Apr; 17(7):2022-5. PubMed ID: 17267217
[TBL] [Abstract][Full Text] [Related]
16. Role of 5-HT(1A) receptors in fluoxetine-induced lordosis inhibition.
Guptarak J; Sarkar J; Hiegel C; Uphouse L
Horm Behav; 2010 Jul; 58(2):290-6. PubMed ID: 20223238
[TBL] [Abstract][Full Text] [Related]
17. Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. part 3.
Herold F; Chodkowski A; Izbicki Ł; Turło J; Dawidowski M; Kleps J; Nowak G; Stachowicz K; Dybała M; Siwek A; Mazurek AP; Mazurek A; Pluciński F
Eur J Med Chem; 2011 Jan; 46(1):142-9. PubMed ID: 21093118
[TBL] [Abstract][Full Text] [Related]
18. Effect of combined administration of 5-HT1A or 5-HT1B/1D receptor antagonists and antidepressants in the forced swimming test.
Tatarczyńska E; Kłodzińska A; Stachowicz K; Chojnacka-Wójcik E
Eur J Pharmacol; 2004 Mar; 487(1-3):133-42. PubMed ID: 15033385
[TBL] [Abstract][Full Text] [Related]
19. Discovery of the first potent, selective 5-hydroxytryptamine1D receptor antagonist.
Ward SE; Harrington FP; Gordon LJ; Hopley SC; Scott CM; Watson JM
J Med Chem; 2005 May; 48(10):3478-80. PubMed ID: 15887956
[TBL] [Abstract][Full Text] [Related]
20. 5-HT 1A/1B receptor-mediated effects of the selective serotonin reuptake inhibitor, citalopram, on sleep: studies in 5-HT 1A and 5-HT 1B knockout mice.
Monaca C; Boutrel B; Hen R; Hamon M; Adrien J
Neuropsychopharmacology; 2003 May; 28(5):850-6. PubMed ID: 12637954
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
