294 related articles for article (PubMed ID: 18829459)
1. Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.
Patel A; Dharmarajan V; Cosgrove MS
J Biol Chem; 2008 Nov; 283(47):32158-61. PubMed ID: 18829459
[TBL] [Abstract][Full Text] [Related]
2. A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.
Patel A; Vought VE; Dharmarajan V; Cosgrove MS
J Biol Chem; 2008 Nov; 283(47):32162-75. PubMed ID: 18829457
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
Dharmarajan V; Lee JH; Patel A; Skalnik DG; Cosgrove MS
J Biol Chem; 2012 Aug; 287(33):27275-89. PubMed ID: 22665483
[TBL] [Abstract][Full Text] [Related]
4. Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.
Alicea-Velázquez NL; Shinsky SA; Loh DM; Lee JH; Skalnik DG; Cosgrove MS
J Biol Chem; 2016 Oct; 291(43):22357-22372. PubMed ID: 27563068
[TBL] [Abstract][Full Text] [Related]
5. Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
Patel A; Vought VE; Swatkoski S; Viggiano S; Howard B; Dharmarajan V; Monteith KE; Kupakuwana G; Namitz KE; Shinsky SA; Cotter RJ; Cosgrove MS
J Biol Chem; 2014 Jan; 289(2):868-84. PubMed ID: 24235145
[TBL] [Abstract][Full Text] [Related]
6. Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.
Karatas H; Townsend EC; Bernard D; Dou Y; Wang S
J Med Chem; 2010 Jul; 53(14):5179-85. PubMed ID: 20575550
[TBL] [Abstract][Full Text] [Related]
7. On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
Patel A; Dharmarajan V; Vought VE; Cosgrove MS
J Biol Chem; 2009 Sep; 284(36):24242-56. PubMed ID: 19556245
[TBL] [Abstract][Full Text] [Related]
8. Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.
Shinsky SA; Cosgrove MS
J Biol Chem; 2015 Oct; 290(43):25819-33. PubMed ID: 26324722
[TBL] [Abstract][Full Text] [Related]
9. The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex.
Han J; Li T; Li Y; Li M; Wang X; Peng C; Su C; Li N; Li Y; Xu Y; Chen Y
Nucleic Acids Res; 2019 Nov; 47(19):10426-10438. PubMed ID: 31544921
[TBL] [Abstract][Full Text] [Related]
10. Structural and biochemical insights into MLL1 core complex assembly.
Avdic V; Zhang P; Lanouette S; Groulx A; Tremblay V; Brunzelle J; Couture JF
Structure; 2011 Jan; 19(1):101-8. PubMed ID: 21220120
[TBL] [Abstract][Full Text] [Related]
11. The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Zhang P; Lee H; Brunzelle JS; Couture JF
Nucleic Acids Res; 2012 May; 40(9):4237-46. PubMed ID: 22266653
[TBL] [Abstract][Full Text] [Related]
12. Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.
Shinsky SA; Monteith KE; Viggiano S; Cosgrove MS
J Biol Chem; 2015 Mar; 290(10):6361-75. PubMed ID: 25561738
[TBL] [Abstract][Full Text] [Related]
13. Characterization of a novel WDR5-binding site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 lysine 4 by mixed lineage leukemia protein-1.
Odho Z; Southall SM; Wilson JR
J Biol Chem; 2010 Oct; 285(43):32967-32976. PubMed ID: 20716525
[TBL] [Abstract][Full Text] [Related]
14. A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.
Shinsky SA; Hu M; Vought VE; Ng SB; Bamshad MJ; Shendure J; Cosgrove MS
J Mol Biol; 2014 Jun; 426(12):2283-99. PubMed ID: 24680668
[TBL] [Abstract][Full Text] [Related]
15. WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket.
Song JJ; Kingston RE
J Biol Chem; 2008 Dec; 283(50):35258-64. PubMed ID: 18840606
[TBL] [Abstract][Full Text] [Related]
16. The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein- Protein Interaction.
Ye X; Chen G; Jin J; Zhang B; Wang Y; Cai Z; Ye F
Curr Med Chem; 2020; 27(33):5530-5542. PubMed ID: 31132972
[TBL] [Abstract][Full Text] [Related]
17. Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Ruthenburg AJ; Wang W; Graybosch DM; Li H; Allis CD; Patel DJ; Verdine GL
Nat Struct Mol Biol; 2006 Aug; 13(8):704-12. PubMed ID: 16829959
[TBL] [Abstract][Full Text] [Related]
18. Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Xue H; Yao T; Cao M; Zhu G; Li Y; Yuan G; Chen Y; Lei M; Huang J
Nature; 2019 Sep; 573(7774):445-449. PubMed ID: 31485071
[TBL] [Abstract][Full Text] [Related]
19. PAQR3 modulates H3K4 trimethylation by spatial modulation of the regulatory subunits of COMPASS-like complexes in mammalian cells.
Liu C; Zhang Y; Hou Y; Shen L; Li Y; Guo W; Xu D; Liu G; Zhao Z; Man K; Pan Y; Wang Z; Chen Y
Biochem J; 2015 May; 467(3):415-24. PubMed ID: 25706881
[TBL] [Abstract][Full Text] [Related]
20. A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.
Patel A; Vought VE; Dharmarajan V; Cosgrove MS
J Biol Chem; 2011 Feb; 286(5):3359-69. PubMed ID: 21106533
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
