227 related articles for article (PubMed ID: 18832479)
1. Key amino acid residues responsible for the differences in substrate specificity of human UDP-glucuronosyltransferase (UGT)1A9 and UGT1A8.
Fujiwara R; Nakajima M; Yamanaka H; Yokoi T
Drug Metab Dispos; 2009 Jan; 37(1):41-6. PubMed ID: 18832479
[TBL] [Abstract][Full Text] [Related]
2. In silico and in vitro approaches to elucidate the thermal stability of human UDP-glucuronosyltransferase (UGT) 1A9.
Fujiwara R; Nakajima M; Yamamoto T; Nagao H; Yokoi T
Drug Metab Pharmacokinet; 2009; 24(3):235-44. PubMed ID: 19571435
[TBL] [Abstract][Full Text] [Related]
3. How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?
Itäaho K; Laakkonen L; Finel M
Drug Metab Dispos; 2010 Apr; 38(4):687-96. PubMed ID: 20089735
[TBL] [Abstract][Full Text] [Related]
4. Amino acid positions 69-132 of UGT1A9 are involved in the C-glucuronidation of phenylbutazone.
Nishiyama T; Fujishima M; Masuda Y; Izawa T; Ohnuma T; Ogura K; Hiratsuka A
Arch Biochem Biophys; 2008 Oct; 478(1):75-80. PubMed ID: 18602884
[TBL] [Abstract][Full Text] [Related]
5. Preparation of a specific monoclonal antibody against human UDP-glucuronosyltransferase (UGT) 1A9 and evaluation of UGT1A9 protein levels in human tissues.
Oda S; Nakajima M; Hatakeyama M; Fukami T; Yokoi T
Drug Metab Dispos; 2012 Aug; 40(8):1620-7. PubMed ID: 22619308
[TBL] [Abstract][Full Text] [Related]
6. Analysis of substrate specificities and tissue expression of rat UDP-glucuronosyltransferases UGT1A7 and UGT1A8.
Webb LJ; Miles KK; Auyeung DJ; Kessler FK; Ritter JK
Drug Metab Dispos; 2005 Jan; 33(1):77-82. PubMed ID: 15502008
[TBL] [Abstract][Full Text] [Related]
7. Influence of N-terminal domain histidine and proline residues on the substrate selectivities of human UDP-glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10.
Kerdpin O; Mackenzie PI; Bowalgaha K; Finel M; Miners JO
Drug Metab Dispos; 2009 Sep; 37(9):1948-55. PubMed ID: 19487247
[TBL] [Abstract][Full Text] [Related]
8. Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity.
Korprasertthaworn P; Rowland A; Lewis BC; Mackenzie PI; Yoovathaworn K; Miners JO
Biochem Pharmacol; 2012 Dec; 84(11):1511-21. PubMed ID: 22981363
[TBL] [Abstract][Full Text] [Related]
9. Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin.
Senay C; Battaglia E; Chen G; Breton R; Fournel-Gigleux S; Magdalou J; Radominska-Pandya A
Arch Biochem Biophys; 1999 Aug; 368(1):75-84. PubMed ID: 10415114
[TBL] [Abstract][Full Text] [Related]
10. Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha.
Barbier O; Girard H; Inoue Y; Duez H; Villeneuve L; Kamiya A; Fruchart JC; Guillemette C; Gonzalez FJ; Staels B
Mol Pharmacol; 2005 Jan; 67(1):241-9. PubMed ID: 15470081
[TBL] [Abstract][Full Text] [Related]
11. Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.
Barre L; Fournel-Gigleux S; Finel M; Netter P; Magdalou J; Ouzzine M
FEBS J; 2007 Mar; 274(5):1256-64. PubMed ID: 17263731
[TBL] [Abstract][Full Text] [Related]
12. Alteration of human UDP-glucuronosyltransferase UGT2B17 regio-specificity by a single amino acid substitution.
Dubois SG; Beaulieu M; Lévesque E; Hum DW; Bélanger A
J Mol Biol; 1999 May; 289(1):29-39. PubMed ID: 10339403
[TBL] [Abstract][Full Text] [Related]
13. Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.
Cheng Z; Radominska-Pandya A; Tephly TR
Drug Metab Dispos; 1999 Oct; 27(10):1165-70. PubMed ID: 10497143
[TBL] [Abstract][Full Text] [Related]
14. Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4.
Bruck M; Li Q; Lamb JG; Tukey RH
Arch Biochem Biophys; 1997 Aug; 344(2):357-64. PubMed ID: 9264550
[TBL] [Abstract][Full Text] [Related]
15. Amino acid residue ILE211 is essential for the enzymatic activity of human UDP-glucuronosyltransferase 1A10 (UGT1A10).
Martineau I; Tchernof A; Bélanger A
Drug Metab Dispos; 2004 Apr; 32(4):455-9. PubMed ID: 15039300
[TBL] [Abstract][Full Text] [Related]
16. A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids.
Pritchard M; Fournel-Gigleux S; Siest G; Mackenzie P; Magdalou J
Mol Pharmacol; 1994 Jan; 45(1):42-50. PubMed ID: 8302279
[TBL] [Abstract][Full Text] [Related]
17. Glucuronidation of thyroxine in human liver, jejunum, and kidney microsomes.
Yamanaka H; Nakajima M; Katoh M; Yokoi T
Drug Metab Dispos; 2007 Sep; 35(9):1642-8. PubMed ID: 17591679
[TBL] [Abstract][Full Text] [Related]
18. Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8.
Strassburg CP; Manns MP; Tukey RH
J Biol Chem; 1998 Apr; 273(15):8719-26. PubMed ID: 9535849
[TBL] [Abstract][Full Text] [Related]
19. Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis.
Xiong Y; Bernardi D; Bratton S; Ward MD; Battaglia E; Finel M; Drake RR; Radominska-Pandya A
Biochemistry; 2006 Feb; 45(7):2322-32. PubMed ID: 16475821
[TBL] [Abstract][Full Text] [Related]
20. Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4alpha.
Gardner-Stephen DA; Mackenzie PI
Pharmacogenet Genomics; 2007 Jan; 17(1):25-36. PubMed ID: 17264800
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]