325 related articles for article (PubMed ID: 18835029)
1. Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets?
Ruiz i Altaba A
Cancer Cell; 2008 Oct; 14(4):281-3. PubMed ID: 18835029
[TBL] [Abstract][Full Text] [Related]
2. Targeting GLI factors to inhibit the Hedgehog pathway.
Infante P; Alfonsi R; Botta B; Mori M; Di Marcotullio L
Trends Pharmacol Sci; 2015 Aug; 36(8):547-58. PubMed ID: 26072120
[TBL] [Abstract][Full Text] [Related]
3. Nonclassical hedgehog-GLI signaling and its clinical implications.
Shevde LA; Samant RS
Int J Cancer; 2014 Jul; 135(1):1-6. PubMed ID: 23929208
[TBL] [Abstract][Full Text] [Related]
4. Targeting hedgehog signaling pathway in pediatric tumors: in vitro evaluation of SMO and GLI inhibitors.
Arnhold V; Boos J; Lanvers-Kaminsky C
Cancer Chemother Pharmacol; 2016 Mar; 77(3):495-505. PubMed ID: 26781311
[TBL] [Abstract][Full Text] [Related]
5. The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity.
Spann AL; Yuan K; Goliwas KF; Steg AD; Kaushik DD; Kwon YJ; Frost AR
Int J Oncol; 2015 Jul; 47(1):269-79. PubMed ID: 25997440
[TBL] [Abstract][Full Text] [Related]
6. Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma.
Mori Y; Okumura T; Tsunoda S; Sakai Y; Shimada Y
Oncology; 2006; 70(5):378-89. PubMed ID: 17179732
[TBL] [Abstract][Full Text] [Related]
7. WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function.
Pandolfi S; Montagnani V; Penachioni JY; Vinci MC; Olivito B; Borgognoni L; Stecca B
Oncogene; 2013 Oct; 32(40):4737-47. PubMed ID: 23146903
[TBL] [Abstract][Full Text] [Related]
8. Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion.
Varnat F; Duquet A; Malerba M; Zbinden M; Mas C; Gervaz P; Ruiz i Altaba A
EMBO Mol Med; 2009 Sep; 1(6-7):338-51. PubMed ID: 20049737
[TBL] [Abstract][Full Text] [Related]
9. Gli as a novel therapeutic target in malignant pleural mesothelioma.
Li H; Lui N; Cheng T; Tseng HH; Yue D; Giroux-Leprieur E; Do HT; Sheng Q; Jin JQ; Luh TW; Jablons DM; He B
PLoS One; 2013; 8(3):e57346. PubMed ID: 23483902
[TBL] [Abstract][Full Text] [Related]
10. Hedgehog signaling and the Gli code in stem cells, cancer, and metastases.
Ruiz i Altaba A
Sci Signal; 2011 Nov; 4(200):pt9. PubMed ID: 22114144
[TBL] [Abstract][Full Text] [Related]
11. Targeting GLI Transcription Factors in Cancer.
Didiasova M; Schaefer L; Wygrecka M
Molecules; 2018 Apr; 23(5):. PubMed ID: 29695137
[TBL] [Abstract][Full Text] [Related]
12. Nanoquinacrine induced apoptosis in cervical cancer stem cells through the inhibition of hedgehog-GLI1 cascade: Role of GLI-1.
Nayak A; Satapathy SR; Das D; Siddharth S; Tripathi N; Bharatam PV; Kundu C
Sci Rep; 2016 Feb; 6():20600. PubMed ID: 26846872
[TBL] [Abstract][Full Text] [Related]
13. Unraveling the therapeutic potential of the Hedgehog pathway in cancer.
Amakye D; Jagani Z; Dorsch M
Nat Med; 2013 Nov; 19(11):1410-22. PubMed ID: 24202394
[TBL] [Abstract][Full Text] [Related]
14. TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling.
Ibuki N; Ghaffari M; Pandey M; Iu I; Fazli L; Kashiwagi M; Tojo H; Nakanishi O; Gleave ME; Cox ME
Int J Cancer; 2013 Oct; 133(8):1955-66. PubMed ID: 23564295
[TBL] [Abstract][Full Text] [Related]
15. Scaffold hopping approach to a new series of smoothened antagonists.
Lu W; Geng D; Sun Z; Yang Z; Ma H; Zheng J; Zhang X
Bioorg Med Chem Lett; 2014 May; 24(10):2300-4. PubMed ID: 24726807
[TBL] [Abstract][Full Text] [Related]
16. Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma.
Lo WW; Wunder JS; Dickson BC; Campbell V; McGovern K; Alman BA; Andrulis IL
Cancer; 2014 Feb; 120(4):537-47. PubMed ID: 24151134
[TBL] [Abstract][Full Text] [Related]
17. Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.
Santini R; Vinci MC; Pandolfi S; Penachioni JY; Montagnani V; Olivito B; Gattai R; Pimpinelli N; Gerlini G; Borgognoni L; Stecca B
Stem Cells; 2012 Sep; 30(9):1808-18. PubMed ID: 22730244
[TBL] [Abstract][Full Text] [Related]
18. Mechanisms of Hedgehog signalling in cancer.
Marini KD; Payne BJ; Watkins DN; Martelotto LG
Growth Factors; 2011 Dec; 29(6):221-34. PubMed ID: 21875383
[TBL] [Abstract][Full Text] [Related]
19. Mitogen-activated protein kinases and Hedgehog-GLI signaling in cancer: A crosstalk providing therapeutic opportunities?
Rovida E; Stecca B
Semin Cancer Biol; 2015 Dec; 35():154-67. PubMed ID: 26292171
[TBL] [Abstract][Full Text] [Related]
20. Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells.
Peiris-Pagès M; Sotgia F; Lisanti MP
Oncotarget; 2015 May; 6(13):10728-45. PubMed ID: 25915429
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]