BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 18836177)

  • 41. The peptide loop consisting of amino acids 139-157 of human granzyme B (fragmentin 2) contains an immunodominant epitope recognized by the mouse.
    Apostolidis VA; Browne KA; Smyth MJ; Trapani JA
    Mol Immunol; 1995 Aug; 32(12):909-17. PubMed ID: 7565817
    [TBL] [Abstract][Full Text] [Related]  

  • 42. The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.
    Srinivasula SM; Fernandes-Alnemri T; Zangrilli J; Robertson N; Armstrong RC; Wang L; Trapani JA; Tomaselli KJ; Litwack G; Alnemri ES
    J Biol Chem; 1996 Oct; 271(43):27099-106. PubMed ID: 8900201
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis.
    Van Damme P; Martens L; Van Damme J; Hugelier K; Staes A; Vandekerckhove J; Gevaert K
    Nat Methods; 2005 Oct; 2(10):771-7. PubMed ID: 16179924
    [TBL] [Abstract][Full Text] [Related]  

  • 44. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.
    Edwards KM; Kam CM; Powers JC; Trapani JA
    J Biol Chem; 1999 Oct; 274(43):30468-73. PubMed ID: 10521426
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates.
    Rukamp BJ; Kam CM; Natarajan S; Bolton BW; Smyth MJ; Kelly JM; Powers JC
    Arch Biochem Biophys; 2004 Feb; 422(1):9-22. PubMed ID: 14725853
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.
    Odake S; Kam CM; Narasimhan L; Poe M; Blake JT; Krahenbuhl O; Tschopp J; Powers JC
    Biochemistry; 1991 Feb; 30(8):2217-27. PubMed ID: 1998680
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Blessing or curse? Proteomics in granzyme research.
    Joeckel LT; Bird PI
    Proteomics Clin Appl; 2014 Jun; 8(5-6):351-81. PubMed ID: 24677694
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
    Estébanez-Perpiña E; Fuentes-Prior P; Belorgey D; Braun M; Kiefersauer R; Maskos K; Huber R; Rubin H; Bode W
    Biol Chem; 2000 Dec; 381(12):1203-14. PubMed ID: 11209755
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Proteolytic post-translational modification of proteins: proteomic tools and methodology.
    Rogers LD; Overall CM
    Mol Cell Proteomics; 2013 Dec; 12(12):3532-42. PubMed ID: 23887885
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Colon tumour secretopeptidome: insights into endogenous proteolytic cleavage events in the colon tumour microenvironment.
    Greening DW; Kapp EA; Ji H; Speed TP; Simpson RJ
    Biochim Biophys Acta; 2013 Nov; 1834(11):2396-407. PubMed ID: 23684732
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Hip is a pro-survival substrate of granzyme B.
    Hostetter DR; Loeb CR; Chu F; Craik CS
    J Biol Chem; 2007 Sep; 282(38):27865-74. PubMed ID: 17620340
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Immunopurification of functional Asp-ase (natural killer cell granzyme B) using a monoclonal antibody.
    Trapani JA; Browne KA; Dawson M; Smyth MJ
    Biochem Biophys Res Commun; 1993 Sep; 195(2):910-20. PubMed ID: 8373425
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Single-Fluorescent Protein Reporters Allow Parallel Quantification of Natural Killer Cell-Mediated Granzyme and Caspase Activities in Single Target Cells.
    Liesche C; Sauer P; Prager I; Urlaub D; Claus M; Eils R; Beaudouin J; Watzl C
    Front Immunol; 2018; 9():1840. PubMed ID: 30135688
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Proteolysis of HIP during apoptosis occurs within a region similar to the BID loop.
    Caruso JA; Reiners JJ
    Apoptosis; 2006 Nov; 11(11):1877-85. PubMed ID: 17013759
    [TBL] [Abstract][Full Text] [Related]  

  • 55. P-4 and RNKP-7, new granzyme-like serine proteases expressed in activated rat lymphocytes.
    Ewoldt GR; Smyth MJ; Darcy PK; Harris JL; Craik CS; Horowitz B; Woodard SL; Powers JC; Hudig D
    J Immunol; 1997 May; 158(10):4574-83. PubMed ID: 9144469
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity.
    Demon D; Van Damme P; Vanden Berghe T; Deceuninck A; Van Durme J; Verspurten J; Helsens K; Impens F; Wejda M; Schymkowitz J; Rousseau F; Madder A; Vandekerckhove J; Declercq W; Gevaert K; Vandenabeele P
    Mol Cell Proteomics; 2009 Dec; 8(12):2700-14. PubMed ID: 19759058
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Cascleave 2.0, a new approach for predicting caspase and granzyme cleavage targets.
    Wang M; Zhao XM; Tan H; Akutsu T; Whisstock JC; Song J
    Bioinformatics; 2014 Jan; 30(1):71-80. PubMed ID: 24149049
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis.
    Trapani JA; Browne KA; Smyth MJ; Jans DA
    J Biol Chem; 1996 Feb; 271(8):4127-33. PubMed ID: 8626751
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Positional proteomics in the era of the human proteome project on the doorstep of precision medicine.
    Eckhard U; Marino G; Butler GS; Overall CM
    Biochimie; 2016 Mar; 122():110-8. PubMed ID: 26542287
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Characterisation of two serine protease inhibitors expressed in the pituitary gland.
    Fell B; Smith AM; Hill RM; Parmar PK; Coates LC; Mezey E; Birch NP
    Arch Physiol Biochem; 2002 Apr; 110(1-2):26-33. PubMed ID: 11935397
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.