BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 18836481)

  • 1. Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis.
    Raafat A; Lawson S; Bargo S; Klauzinska M; Strizzi L; Goldhar AS; Buono K; Salomon D; Vonderhaar BK; Callahan R
    Oncogene; 2009 Jan; 28(2):219-30. PubMed ID: 18836481
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ANK repeats of Notch-4/Int3 activate NF-κB canonical pathway in the absence of Rbpj and causes mammary tumorigenesis.
    Raafat A; Bargo S; McCurdy D; Callahan R
    Sci Rep; 2017 Oct; 7(1):13690. PubMed ID: 29057904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
    Gallahan D; Jhappan C; Robinson G; Hennighausen L; Sharp R; Kordon E; Callahan R; Merlino G; Smith GH
    Cancer Res; 1996 Apr; 56(8):1775-85. PubMed ID: 8620493
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kit and PDGFR-alpha activities are necessary for Notch4/Int3-induced tumorigenesis.
    Raafat A; Zoltan-Jones A; Strizzi L; Bargo S; Kimura K; Salomon D; Callahan R
    Oncogene; 2007 Feb; 26(5):662-72. PubMed ID: 16878155
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammary development and tumorigenesis in mice expressing a truncated human Notch4/Int3 intracellular domain (h-Int3sh).
    Raafat A; Bargo S; Anver MR; Callahan R
    Oncogene; 2004 Dec; 23(58):9401-7. PubMed ID: 15531924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor.
    Bruno RD; Boulanger CA; Smith GH
    Oncogene; 2012 Jan; 31(1):60-7. PubMed ID: 21666720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Original Research: Featured Article: Imatinib mesylate (Gleevec) inhibits Notch and c-Myc signaling: Five-day treatment permanently rescues mammary development.
    Callahan R; Chestnut BA; Raafat A
    Exp Biol Med (Maywood); 2017 Jan; 242(1):53-67. PubMed ID: 27550925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeats.
    Bargo S; Raafat A; McCurdy D; Amirjazil I; Shu Y; Traicoff J; Plant J; Vonderhaar BK; Callahan R
    Biochem Biophys Res Commun; 2010 Oct; 400(4):606-12. PubMed ID: 20804727
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene.
    Robinson GW; Wagner KU; Hennighausen L
    Oncogene; 2001 Oct; 20(48):7115-9. PubMed ID: 11704837
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4).
    Gallahan D; Callahan R
    Oncogene; 1997 Apr; 14(16):1883-90. PubMed ID: 9150355
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing events.
    Lee JS; Haruna T; Ishimoto A; Honjo T; Yanagawa S
    J Virol; 1999 Jun; 73(6):5166-71. PubMed ID: 10233982
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of human Cripto-1 in transgenic mice delays mammary gland development and differentiation and induces mammary tumorigenesis.
    Sun Y; Strizzi L; Raafat A; Hirota M; Bianco C; Feigenbaum L; Kenney N; Wechselberger C; Callahan R; Salomon DS
    Am J Pathol; 2005 Aug; 167(2):585-97. PubMed ID: 16049342
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development.
    Smith GH; Gallahan D; Diella F; Jhappan C; Merlino G; Callahan R
    Cell Growth Differ; 1995 May; 6(5):563-77. PubMed ID: 7544153
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.
    Hirner H; Günes C; Bischof J; Wolff S; Grothey A; Kühl M; Oswald F; Wegwitz F; Bösl MR; Trauzold A; Henne-Bruns D; Peifer C; Leithäuser F; Deppert W; Knippschild U
    PLoS One; 2012; 7(1):e29709. PubMed ID: 22235331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Understanding mammary gland development through the imbalanced expression of growth regulators.
    Robinson GW; Smith GH; Gallahan D; Zimmer A; Furth PA; Hennighausen L
    Dev Dyn; 1996 Jun; 206(2):159-68. PubMed ID: 8725283
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice.
    Sandgren EP; Schroeder JA; Qui TH; Palmiter RD; Brinster RL; Lee DC
    Cancer Res; 1995 Sep; 55(17):3915-27. PubMed ID: 7641211
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.
    White DE; Cardiff RD; Dedhar S; Muller WJ
    Oncogene; 2001 Oct; 20(48):7064-72. PubMed ID: 11704830
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch signaling in mammary gland tumorigenesis.
    Callahan R; Raafat A
    J Mammary Gland Biol Neoplasia; 2001 Jan; 6(1):23-36. PubMed ID: 11467450
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Whey acidic protein extrinsically expressed from the mouse mammary tumor virus long terminal repeat results in hyperplasia of the coagulation gland epithelium and impaired mammary development.
    Hennighausen L; McKnight R; Burdon T; Baik M; Wall RJ; Smith GH
    Cell Growth Differ; 1994 Jun; 5(6):607-13. PubMed ID: 7522033
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription.
    Schoenenberger CA; Andres AC; Groner B; van der Valk M; LeMeur M; Gerlinger P
    EMBO J; 1988 Jan; 7(1):169-75. PubMed ID: 2834201
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.