158 related articles for article (PubMed ID: 18836482)
21. Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice.
Hinault C; Mothe-Satney I; Gautier N; Lawrence JC; Van Obberghen E
FASEB J; 2004 Dec; 18(15):1894-6. PubMed ID: 15479767
[TBL] [Abstract][Full Text] [Related]
22. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.
Brunn GJ; Williams J; Sabers C; Wiederrecht G; Lawrence JC; Abraham RT
EMBO J; 1996 Oct; 15(19):5256-67. PubMed ID: 8895571
[TBL] [Abstract][Full Text] [Related]
23. mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.
Holz MK; Ballif BA; Gygi SP; Blenis J
Cell; 2005 Nov; 123(4):569-80. PubMed ID: 16286006
[TBL] [Abstract][Full Text] [Related]
24. Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein.
Fraser CS; Pain VM; Morley SJ
Biochem J; 1999 Sep; 342 Pt 3(Pt 3):519-26. PubMed ID: 10477262
[TBL] [Abstract][Full Text] [Related]
25. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
Coutant A; Rescan C; Gilot D; Loyer P; Guguen-Guillouzo C; Baffet G
Hepatology; 2002 Nov; 36(5):1079-88. PubMed ID: 12395317
[TBL] [Abstract][Full Text] [Related]
26. LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms.
Kristof AS; Pacheco-Rodriguez G; Schremmer B; Moss J
J Pharmacol Exp Ther; 2005 Sep; 314(3):1134-43. PubMed ID: 15923340
[TBL] [Abstract][Full Text] [Related]
27. Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.
Sun SY; Rosenberg LM; Wang X; Zhou Z; Yue P; Fu H; Khuri FR
Cancer Res; 2005 Aug; 65(16):7052-8. PubMed ID: 16103051
[TBL] [Abstract][Full Text] [Related]
28. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
[TBL] [Abstract][Full Text] [Related]
29. Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated.
Suryawan A; Orellana RA; Nguyen HV; Jeyapalan AS; Fleming JR; Davis TA
Am J Physiol Endocrinol Metab; 2007 Dec; 293(6):E1597-605. PubMed ID: 17878222
[TBL] [Abstract][Full Text] [Related]
30. Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells.
Bhandari BK; Feliers D; Duraisamy S; Stewart JL; Gingras AC; Abboud HE; Choudhury GG; Sonenberg N; Kasinath BS
Kidney Int; 2001 Mar; 59(3):866-75. PubMed ID: 11231341
[TBL] [Abstract][Full Text] [Related]
31. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
[TBL] [Abstract][Full Text] [Related]
32. Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.
Navé BT; Ouwens M; Withers DJ; Alessi DR; Shepherd PR
Biochem J; 1999 Dec; 344 Pt 2(Pt 2):427-31. PubMed ID: 10567225
[TBL] [Abstract][Full Text] [Related]
33. Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
Cao X; Kambe F; Moeller LC; Refetoff S; Seo H
Mol Endocrinol; 2005 Jan; 19(1):102-12. PubMed ID: 15388791
[TBL] [Abstract][Full Text] [Related]
34. Evidence that the dephosphorylation of Ser(535) in the epsilon-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin.
Wang X; Janmaat M; Beugnet A; Paulin FE; Proud CG
Biochem J; 2002 Oct; 367(Pt 2):475-81. PubMed ID: 12133000
[TBL] [Abstract][Full Text] [Related]
35. Muscarinic acetylcholine receptors mediate eIF4B phosphorylation in SNU-407 colon cancer cells.
Liu Z; Cho NJ
Biochem Biophys Res Commun; 2016 Nov; 480(3):450-454. PubMed ID: 27773818
[TBL] [Abstract][Full Text] [Related]
36. Bone morphogenetic protein-2-induced transformation involves the activation of mammalian target of rapamycin.
Langenfeld EM; Kong Y; Langenfeld J
Mol Cancer Res; 2005 Dec; 3(12):679-84. PubMed ID: 16380505
[TBL] [Abstract][Full Text] [Related]
37. Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates mTOR signal pathways and protein translation in the rat frontal cortex.
Kim SH; Yu HS; Park HG; Ha K; Kim YS; Shin SY; Ahn YM
Prog Neuropsychopharmacol Biol Psychiatry; 2013 Aug; 45():73-82. PubMed ID: 23643758
[TBL] [Abstract][Full Text] [Related]
38. Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40.
Vander Haar E; Lee SI; Bandhakavi S; Griffin TJ; Kim DH
Nat Cell Biol; 2007 Mar; 9(3):316-23. PubMed ID: 17277771
[TBL] [Abstract][Full Text] [Related]
39. Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
RodrĂguez-Escudero I; Roelants FM; Thorner J; Nombela C; Molina M; Cid VJ
Biochem J; 2005 Sep; 390(Pt 2):613-23. PubMed ID: 15913452
[TBL] [Abstract][Full Text] [Related]
40. Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.
Wang Y; Begley M; Li Q; Huang HT; Lako A; Eck MJ; Gray NS; Mitchison TJ; Cantley LC; Zhao JJ
Proc Natl Acad Sci U S A; 2016 Aug; 113(35):9810-5. PubMed ID: 27528663
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]