BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

457 related articles for article (PubMed ID: 18842585)

  • 1. G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates.
    Creacy SD; Routh ED; Iwamoto F; Nagamine Y; Akman SA; Vaughn JP
    J Biol Chem; 2008 Dec; 283(50):34626-34. PubMed ID: 18842585
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates.
    Vaughn JP; Creacy SD; Routh ED; Joyner-Butt C; Jenkins GS; Pauli S; Nagamine Y; Akman SA
    J Biol Chem; 2005 Nov; 280(46):38117-20. PubMed ID: 16150737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA.
    Giri B; Smaldino PJ; Thys RG; Creacy SD; Routh ED; Hantgan RR; Lattmann S; Nagamine Y; Akman SA; Vaughn JP
    Nucleic Acids Res; 2011 Sep; 39(16):7161-78. PubMed ID: 21586581
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G-quadruplexes unfolding by RHAU helicase.
    Gueddouda NM; Mendoza O; Gomez D; Bourdoncle A; Mergny JL
    Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1382-1388. PubMed ID: 28065761
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU).
    Meier M; Patel TR; Booy EP; Marushchak O; Okun N; Deo S; Howard R; McEleney K; Harding SE; Stetefeld J; McKenna SA
    J Biol Chem; 2013 Dec; 288(49):35014-27. PubMed ID: 24151078
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.
    Routh ED; Creacy SD; Beerbower PE; Akman SA; Vaughn JP; Smaldino PJ
    J Vis Exp; 2017 Mar; (121):. PubMed ID: 28362374
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU.
    Lattmann S; Giri B; Vaughn JP; Akman SA; Nagamine Y
    Nucleic Acids Res; 2010 Oct; 38(18):6219-33. PubMed ID: 20472641
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.
    Smaldino PJ; Routh ED; Kim JH; Giri B; Creacy SD; Hantgan RR; Akman SA; Vaughn JP
    PLoS One; 2015; 10(7):e0132668. PubMed ID: 26172836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex.
    Heddi B; Cheong VV; Schmitt E; Mechulam Y; Phan AT
    J Struct Biol; 2020 Jan; 209(1):107399. PubMed ID: 31586599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. To unwind the biological knots: The DNA/RNA G-quadruplex resolvase RHAU (DHX36) in development and disease.
    Yang C; Yao J; Yi H; Huang X; Zhao W; Yang Z
    Animal Model Exp Med; 2022 Dec; 5(6):542-549. PubMed ID: 35789129
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation.
    Gao X; Ma W; Nie J; Zhang C; Zhang J; Yao G; Han J; Xu J; Hu B; Du Y; Shi Q; Yang Z; Huang X; Zhang Y
    Cell Death Dis; 2015 Jan; 6(1):e1610. PubMed ID: 25611385
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex.
    Heddi B; Cheong VV; Martadinata H; Phan AT
    Proc Natl Acad Sci U S A; 2015 Aug; 112(31):9608-13. PubMed ID: 26195789
    [TBL] [Abstract][Full Text] [Related]  

  • 13. G-Quadruplexes and the DNA/RNA helicase DHX36 in health, disease, and aging.
    Antcliff A; McCullough LD; Tsvetkov AS
    Aging (Albany NY); 2021 Dec; 13(23):25578-25587. PubMed ID: 34862880
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RNA Helicase Associated with AU-rich Element (RHAU/DHX36) Interacts with the 3'-Tail of the Long Non-coding RNA BC200 (BCYRN1).
    Booy EP; McRae EK; Howard R; Deo SR; Ariyo EO; Dzananovic E; Meier M; Stetefeld J; McKenna SA
    J Biol Chem; 2016 Mar; 291(10):5355-72. PubMed ID: 26740632
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary.
    Booy EP; Meier M; Okun N; Novakowski SK; Xiong S; Stetefeld J; McKenna SA
    Nucleic Acids Res; 2012 May; 40(9):4110-24. PubMed ID: 22238380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
    Chen MC; Tippana R; Demeshkina NA; Murat P; Balasubramanian S; Myong S; Ferré-D'Amaré AR
    Nature; 2018 Jun; 558(7710):465-469. PubMed ID: 29899445
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The DHX36-specific-motif (DSM) enhances specificity by accelerating recruitment of DNA G-quadruplex structures.
    Chang-Gu B; Bradburn D; Yangyuoru PM; Russell R
    Biol Chem; 2021 Apr; 402(5):593-604. PubMed ID: 33857359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The G-quadruplex (G4) resolvase DHX36 efficiently and specifically disrupts DNA G4s via a translocation-based helicase mechanism.
    Yangyuoru PM; Bradburn DA; Liu Z; Xiao TS; Russell R
    J Biol Chem; 2018 Feb; 293(6):1924-1932. PubMed ID: 29269411
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme.
    Lattmann S; Stadler MB; Vaughn JP; Akman SA; Nagamine Y
    Nucleic Acids Res; 2011 Nov; 39(21):9390-404. PubMed ID: 21846770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU.
    Ariyo EO; Booy EP; Patel TR; Dzananovic E; McRae EK; Meier M; McEleney K; Stetefeld J; McKenna SA
    PLoS One; 2015; 10(12):e0144510. PubMed ID: 26649896
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.