281 related articles for article (PubMed ID: 18842593)
1. Rheb and mTOR regulate neuronal polarity through Rap1B.
Li YH; Werner H; Püschel AW
J Biol Chem; 2008 Nov; 283(48):33784-92. PubMed ID: 18842593
[TBL] [Abstract][Full Text] [Related]
2. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.
Tee AR; Manning BD; Roux PP; Cantley LC; Blenis J
Curr Biol; 2003 Aug; 13(15):1259-68. PubMed ID: 12906785
[TBL] [Abstract][Full Text] [Related]
3. RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.
Villalonga P; Fernández de Mattos S; Ridley AJ
J Biol Chem; 2009 Dec; 284(51):35287-96. PubMed ID: 19850923
[TBL] [Abstract][Full Text] [Related]
4. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses.
Smith EM; Finn SG; Tee AR; Browne GJ; Proud CG
J Biol Chem; 2005 May; 280(19):18717-27. PubMed ID: 15772076
[TBL] [Abstract][Full Text] [Related]
5. Raptor and Rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1).
Ge Y; Yoon MS; Chen J
J Biol Chem; 2011 Oct; 286(41):35675-35682. PubMed ID: 21852229
[TBL] [Abstract][Full Text] [Related]
6. Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity.
Schwamborn JC; Müller M; Becker AH; Püschel AW
EMBO J; 2007 Mar; 26(5):1410-22. PubMed ID: 17318188
[TBL] [Abstract][Full Text] [Related]
7. Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.
Sato T; Nakashima A; Guo L; Tamanoi F
J Biol Chem; 2009 May; 284(19):12783-91. PubMed ID: 19299511
[TBL] [Abstract][Full Text] [Related]
8. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the Rheb-mTOR signaling pathway in mammalian cells: constitutive active mutants of Rheb and mTOR.
Sato T; Umetsu A; Tamanoi F
Methods Enzymol; 2008; 438():307-20. PubMed ID: 18413257
[TBL] [Abstract][Full Text] [Related]
10. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.
Garami A; Zwartkruis FJ; Nobukuni T; Joaquin M; Roccio M; Stocker H; Kozma SC; Hafen E; Bos JL; Thomas G
Mol Cell; 2003 Jun; 11(6):1457-66. PubMed ID: 12820960
[TBL] [Abstract][Full Text] [Related]
11. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
Wang X; Beugnet A; Murakami M; Yamanaka S; Proud CG
Mol Cell Biol; 2005 Apr; 25(7):2558-72. PubMed ID: 15767663
[TBL] [Abstract][Full Text] [Related]
12. Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period.
Tamai T; Yamaguchi O; Hikoso S; Takeda T; Taneike M; Oka T; Oyabu J; Murakawa T; Nakayama H; Uno Y; Horie K; Nishida K; Sonenberg N; Shah AM; Takeda J; Komuro I; Otsu K
J Biol Chem; 2013 Apr; 288(14):10176-10187. PubMed ID: 23426372
[TBL] [Abstract][Full Text] [Related]
13. Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.
Zhou Q; Liu C; Liu W; Zhang H; Zhang R; Liu J; Zhang J; Xu C; Liu L; Huang S; Chen L
Toxicol Sci; 2015 Jan; 143(1):81-96. PubMed ID: 25304210
[TBL] [Abstract][Full Text] [Related]
14. AAV transduction of dopamine neurons with constitutively active Rheb protects from neurodegeneration and mediates axon regrowth.
Kim SR; Kareva T; Yarygina O; Kholodilov N; Burke RE
Mol Ther; 2012 Feb; 20(2):275-86. PubMed ID: 22008911
[TBL] [Abstract][Full Text] [Related]
15. REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch.
Miyazaki M; Esser KA
Am J Physiol Cell Physiol; 2009 Mar; 296(3):C583-92. PubMed ID: 19129461
[TBL] [Abstract][Full Text] [Related]
16. Rheb binds and regulates the mTOR kinase.
Long X; Lin Y; Ortiz-Vega S; Yonezawa K; Avruch J
Curr Biol; 2005 Apr; 15(8):702-13. PubMed ID: 15854902
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
[TBL] [Abstract][Full Text] [Related]
18. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
Schalm SS; Fingar DC; Sabatini DM; Blenis J
Curr Biol; 2003 May; 13(10):797-806. PubMed ID: 12747827
[TBL] [Abstract][Full Text] [Related]
19. Molecular mechanisms through which amino acids mediate signaling through the mammalian target of rapamycin.
Kimball SR; Jefferson LS
Curr Opin Clin Nutr Metab Care; 2004 Jan; 7(1):39-44. PubMed ID: 15090902
[TBL] [Abstract][Full Text] [Related]
20. Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells.
Mariappan MM; Shetty M; Sataranatarajan K; Choudhury GG; Kasinath BS
J Biol Chem; 2008 Nov; 283(45):30566-75. PubMed ID: 18701453
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
