281 related articles for article (PubMed ID: 18842593)
21. Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain.
Yu J; Henske EP
Cancer Res; 2006 Oct; 66(19):9461-6. PubMed ID: 17018601
[TBL] [Abstract][Full Text] [Related]
22. Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Mavrakis KJ; Zhu H; Silva RL; Mills JR; Teruya-Feldstein J; Lowe SW; Tam W; Pelletier J; Wendel HG
Genes Dev; 2008 Aug; 22(16):2178-88. PubMed ID: 18708578
[TBL] [Abstract][Full Text] [Related]
23. Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase.
Yan L; Findlay GM; Jones R; Procter J; Cao Y; Lamb RF
J Biol Chem; 2006 Jul; 281(29):19793-7. PubMed ID: 16728407
[TBL] [Abstract][Full Text] [Related]
24. Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.
Miloslavski R; Cohen E; Avraham A; Iluz Y; Hayouka Z; Kasir J; Mudhasani R; Jones SN; Cybulski N; Rüegg MA; Larsson O; Gandin V; Rajakumar A; Topisirovic I; Meyuhas O
J Mol Cell Biol; 2014 Jun; 6(3):255-66. PubMed ID: 24627160
[TBL] [Abstract][Full Text] [Related]
25. mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging.
Yadav RB; Burgos P; Parker AW; Iadevaia V; Proud CG; Allen RA; O'Connell JP; Jeshtadi A; Stubbs CD; Botchway SW
BMC Cell Biol; 2013 Jan; 14():3. PubMed ID: 23311891
[TBL] [Abstract][Full Text] [Related]
26. Phospholipase D1 is an effector of Rheb in the mTOR pathway.
Sun Y; Fang Y; Yoon MS; Zhang C; Roccio M; Zwartkruis FJ; Armstrong M; Brown HA; Chen J
Proc Natl Acad Sci U S A; 2008 Jun; 105(24):8286-91. PubMed ID: 18550814
[TBL] [Abstract][Full Text] [Related]
27. The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer.
Ding M; Van der Kwast TH; Vellanki RN; Foltz WD; McKee TD; Sonenberg N; Pandolfi PP; Koritzinsky M; Wouters BG
Mol Cancer Res; 2018 Apr; 16(4):682-695. PubMed ID: 29453322
[TBL] [Abstract][Full Text] [Related]
28. A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy.
Goodman CA; Miu MH; Frey JW; Mabrey DM; Lincoln HC; Ge Y; Chen J; Hornberger TA
Mol Biol Cell; 2010 Sep; 21(18):3258-68. PubMed ID: 20668162
[TBL] [Abstract][Full Text] [Related]
29. Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
Lekmine F; Uddin S; Sassano A; Parmar S; Brachmann SM; Majchrzak B; Sonenberg N; Hay N; Fish EN; Platanias LC
J Biol Chem; 2003 Jul; 278(30):27772-80. PubMed ID: 12759354
[TBL] [Abstract][Full Text] [Related]
30. Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.
Nakamura T; Yasuda S; Nagai H; Koinuma S; Morishita S; Goto A; Kinashi T; Wada N
Genes Cells; 2013 Nov; 18(11):1020-31. PubMed ID: 24165023
[TBL] [Abstract][Full Text] [Related]
31. Point mutations of the mTOR-RHEB pathway in renal cell carcinoma.
Ghosh AP; Marshall CB; Coric T; Shim EH; Kirkman R; Ballestas ME; Ikura M; Bjornsti MA; Sudarshan S
Oncotarget; 2015 Jul; 6(20):17895-910. PubMed ID: 26255626
[TBL] [Abstract][Full Text] [Related]
32. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.
Gingras AC; Gygi SP; Raught B; Polakiewicz RD; Abraham RT; Hoekstra MF; Aebersold R; Sonenberg N
Genes Dev; 1999 Jun; 13(11):1422-37. PubMed ID: 10364159
[TBL] [Abstract][Full Text] [Related]
33. Rheb, an activator of target of rapamycin, in the blackback land crab, Gecarcinus lateralis: cloning and effects of molting and unweighting on expression in skeletal muscle.
MacLea KS; Abuhagr AM; Pitts NL; Covi JA; Bader BD; Chang ES; Mykles DL
J Exp Biol; 2012 Feb; 215(Pt 4):590-604. PubMed ID: 22279066
[TBL] [Abstract][Full Text] [Related]
34. Hypoxia-induced energy stress regulates mRNA translation and cell growth.
Liu L; Cash TP; Jones RG; Keith B; Thompson CB; Simon MC
Mol Cell; 2006 Feb; 21(4):521-31. PubMed ID: 16483933
[TBL] [Abstract][Full Text] [Related]
35. Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.
Altman MK; Alshamrani AA; Jia W; Nguyen HT; Fambrough JM; Tran SK; Patel MB; Hoseinzadeh P; Beedle AM; Murph MM
Cancer Lett; 2015 Dec; 369(1):175-83. PubMed ID: 26319900
[TBL] [Abstract][Full Text] [Related]
36. Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency.
Long X; Ortiz-Vega S; Lin Y; Avruch J
J Biol Chem; 2005 Jun; 280(25):23433-6. PubMed ID: 15878852
[TBL] [Abstract][Full Text] [Related]
37. Rheb activation of mTOR and S6K1 signaling.
Hanrahan J; Blenis J
Methods Enzymol; 2006; 407():542-55. PubMed ID: 16757352
[TBL] [Abstract][Full Text] [Related]
38. Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
Pham PT; Heydrick SJ; Fox HL; Kimball SR; Jefferson LS; Lynch CJ
J Cell Biochem; 2000 Sep; 79(3):427-41. PubMed ID: 10972980
[TBL] [Abstract][Full Text] [Related]
39. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M; Cash T; Cheung M; Robertson GP; Astrinidis A; Henske EP
J Biol Chem; 2004 Jul; 279(29):29930-7. PubMed ID: 15150271
[TBL] [Abstract][Full Text] [Related]
40. Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb.
Li Y; Wang Y; Kim E; Beemiller P; Wang CY; Swanson J; You M; Guan KL
J Biol Chem; 2007 Dec; 282(49):35803-13. PubMed ID: 17928295
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]