BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 18846109)

  • 1. Tumour cell survival signalling by the ERK1/2 pathway.
    Balmanno K; Cook SJ
    Cell Death Differ; 2009 Mar; 16(3):368-77. PubMed ID: 18846109
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.
    Gillings AS; Balmanno K; Wiggins CM; Johnson M; Cook SJ
    FEBS J; 2009 Nov; 276(21):6050-62. PubMed ID: 19788418
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.
    Sheridan C; Brumatti G; Martin SJ
    J Biol Chem; 2008 Aug; 283(32):22128-35. PubMed ID: 18508762
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
    Wang YF; Jiang CC; Kiejda KA; Gillespie S; Zhang XD; Hersey P
    Clin Cancer Res; 2007 Aug; 13(16):4934-42. PubMed ID: 17652623
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK and RAF inhibitors for BRAF-mutated cancers.
    Belden S; Flaherty KT
    Expert Rev Mol Med; 2012 Oct; 14():e17. PubMed ID: 23058743
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic.
    Cragg MS; Jansen ES; Cook M; Harris C; Strasser A; Scott CL
    J Clin Invest; 2008 Nov; 118(11):3651-9. PubMed ID: 18949058
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BAFF regulates B cell survival by downregulating the BH3-only family member Bim via the ERK pathway.
    Craxton A; Draves KE; Gruppi A; Clark EA
    J Exp Med; 2005 Nov; 202(10):1363-74. PubMed ID: 16301744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.
    Zhang W; Konopleva M; Burks JK; Dywer KC; Schober WD; Yang JY; McQueen TJ; Hung MC; Andreeff M
    Cancer Res; 2010 Mar; 70(6):2424-34. PubMed ID: 20215498
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades.
    Shi GX; Andres DA
    Mol Cell Biol; 2005 Jan; 25(2):830-46. PubMed ID: 15632082
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BCR/ABL activates Rap1 and B-Raf to stimulate the MEK/Erk signaling pathway in hematopoietic cells.
    Mizuchi D; Kurosu T; Kida A; Jin ZH; Jin A; Arai A; Miura O
    Biochem Biophys Res Commun; 2005 Jan; 326(3):645-51. PubMed ID: 15596148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bcl-2 protects endothelial cells against gamma-radiation via a Raf-MEK-ERK-survivin signaling pathway that is independent of cytochrome c release.
    Kumar P; Coltas IK; Kumar B; Chepeha DB; Bradford CR; Polverini PJ
    Cancer Res; 2007 Feb; 67(3):1193-202. PubMed ID: 17283155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NRAS mutation causes a human autoimmune lymphoproliferative syndrome.
    Oliveira JB; Bidère N; Niemela JE; Zheng L; Sakai K; Nix CP; Danner RL; Barb J; Munson PJ; Puck JM; Dale J; Straus SE; Fleisher TA; Lenardo MJ
    Proc Natl Acad Sci U S A; 2007 May; 104(21):8953-8. PubMed ID: 17517660
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.
    Jazirehi AR; Vega MI; Chatterjee D; Goodglick L; Bonavida B
    Cancer Res; 2004 Oct; 64(19):7117-26. PubMed ID: 15466208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib--the role of extracellular signal-regulated kinase counteraction.
    Manov I; Pollak Y; Broneshter R; Iancu TC
    FEBS J; 2011 Sep; 278(18):3494-507. PubMed ID: 21790999
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling.
    Cook SJ; Stuart K; Gilley R; Sale MJ
    FEBS J; 2017 Dec; 284(24):4177-4195. PubMed ID: 28548464
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Decreases in phosphoinositide-3-kinase/Akt and extracellular signal-regulated kinase 1/2 signaling activate components of spinal motoneuron death.
    Newbern J; Taylor A; Robinson M; Li L; Milligan CE
    J Neurochem; 2005 Sep; 94(6):1652-65. PubMed ID: 16045454
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BCR/ABL and IL-3 activate Rap1 to stimulate the B-Raf/MEK/Erk and Akt signaling pathways and to regulate proliferation, apoptosis, and adhesion.
    Jin A; Kurosu T; Tsuji K; Mizuchi D; Arai A; Fujita H; Hattori M; Minato N; Miura O
    Oncogene; 2006 Jul; 25(31):4332-40. PubMed ID: 16518411
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel indoloquinoline derivative, IQDMA, inhibits STAT5 signaling associated with apoptosis in K562 cells.
    Yang SH; Chien CM; Su JC; Chen YL; Chang LS; Lin SR
    J Biochem Mol Toxicol; 2008; 22(6):396-404. PubMed ID: 19111001
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors.
    Shinjyo T; Kuribara R; Inukai T; Hosoi H; Kinoshita T; Miyajima A; Houghton PJ; Look AT; Ozawa K; Inaba T
    Mol Cell Biol; 2001 Feb; 21(3):854-64. PubMed ID: 11154272
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
    Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.