BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 18851840)

  • 1. Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.
    Partovian C; Ju R; Zhuang ZW; Martin KA; Simons M
    Mol Cell; 2008 Oct; 32(1):140-9. PubMed ID: 18851840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
    Wang S; Amato KR; Song W; Youngblood V; Lee K; Boothby M; Brantley-Sieders DM; Chen J
    Mol Cell Biol; 2015 Apr; 35(7):1299-313. PubMed ID: 25582201
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
    Guertin DA; Stevens DM; Thoreen CC; Burds AA; Kalaany NY; Moffat J; Brown M; Fitzgerald KJ; Sabatini DM
    Dev Cell; 2006 Dec; 11(6):859-71. PubMed ID: 17141160
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Syndecan 4 regulation of PDK1-dependent Akt activation.
    Ju R; Simons M
    Cell Signal; 2013 Jan; 25(1):101-5. PubMed ID: 22975683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2.
    Li W; Petrimpol M; Molle KD; Hall MN; Battegay EJ; Humar R
    Circ Res; 2007 Jan; 100(1):79-87. PubMed ID: 17110594
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
    Lee D; Sykes SM; Kalaitzidis D; Lane AA; Kfoury Y; Raaijmakers MH; Wang YH; Armstrong SA; Scadden DT
    Stem Cell Reports; 2014 Nov; 3(5):832-40. PubMed ID: 25418727
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IKK interacts with rictor and regulates mTORC2.
    Xu Y; Lai E; Liu J; Lin J; Yang C; Jia C; Li Y; Bai X; Li M
    Cell Signal; 2013 Nov; 25(11):2239-45. PubMed ID: 23872070
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH; Park YH; Kwon JH; Lee JH; Kim IY
    Biochim Biophys Acta; 2013 Oct; 1833(10):2135-42. PubMed ID: 23680186
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the PI3K-Akt and mTORC1 signaling pathways promotes the elongation of vascular endothelial cells.
    Tsuji-Tamura K; Ogawa M
    J Cell Sci; 2016 Mar; 129(6):1165-78. PubMed ID: 26826185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibitory effect of 14,15-EET on endothelial senescence through activation of mTOR complex 2/Akt signaling pathways.
    Yang C; Pan S; Yan S; Li Z; Yang J; Wang Y; Xiong Y
    Int J Biochem Cell Biol; 2014 May; 50():93-100. PubMed ID: 24607498
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rapamycin regulates the phosphorylation of rictor.
    Akcakanat A; Singh G; Hung MC; Meric-Bernstam F
    Biochem Biophys Res Commun; 2007 Oct; 362(2):330-3. PubMed ID: 17707343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.
    Elfenbein A; Rhodes JM; Meller J; Schwartz MA; Matsuda M; Simons M
    J Cell Biol; 2009 Jul; 186(1):75-83. PubMed ID: 19581409
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis.
    Kim EK; Yun SJ; Ha JM; Kim YW; Jin IH; Yun J; Shin HK; Song SH; Kim JH; Lee JS; Kim CD; Bae SS
    Oncogene; 2011 Jun; 30(26):2954-63. PubMed ID: 21339740
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis.
    Li J; Ren J; Liu X; Jiang L; He W; Yuan W; Yang J; Dai C
    Kidney Int; 2015 Sep; 88(3):515-27. PubMed ID: 25970154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High prevalence of mTOR complex activity can be targeted using Torin2 in papillary thyroid carcinoma.
    Ahmed M; Hussain AR; Bavi P; Ahmed SO; Al Sobhi SS; Al-Dayel F; Uddin S; Al-Kuraya KS
    Carcinogenesis; 2014 Jul; 35(7):1564-72. PubMed ID: 24583924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
    Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R
    Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.
    Misra UK; Pizzo SV
    J Cell Biochem; 2012 May; 113(5):1488-500. PubMed ID: 22173835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 17ß-Estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodeling.
    Kusch A; Schmidt M; Gürgen D; Postpieszala D; Catar R; Hegner B; Davidson MM; Mahmoodzadeh S; Dragun D
    PLoS One; 2015; 10(4):e0123385. PubMed ID: 25880554
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.
    Liu P; Gan W; Chin YR; Ogura K; Guo J; Zhang J; Wang B; Blenis J; Cantley LC; Toker A; Su B; Wei W
    Cancer Discov; 2015 Nov; 5(11):1194-209. PubMed ID: 26293922
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of syndecan-4 side chains in turkey satellite cell apoptosis and focal adhesion formation.
    Song Y; McFarland DC; Velleman SG
    Cell Biol Int; 2012 May; 36(5):433-40. PubMed ID: 22272563
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.