BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

734 related articles for article (PubMed ID: 18854158)

  • 1. Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
    Williams RS; Moncalian G; Williams JS; Yamada Y; Limbo O; Shin DS; Groocock LM; Cahill D; Hitomi C; Guenther G; Moiani D; Carney JP; Russell P; Tainer JA
    Cell; 2008 Oct; 135(1):97-109. PubMed ID: 18854158
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
    Limbo O; Moiani D; Kertokalio A; Wyman C; Tainer JA; Russell P
    Nucleic Acids Res; 2012 Dec; 40(22):11435-49. PubMed ID: 23080121
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutation of Conserved Mre11 Residues Alter Protein Dynamics to Separate Nuclease Functions.
    Rahman S; Beikzadeh M; Canny MD; Kaur N; Latham MP
    J Mol Biol; 2020 May; 432(10):3289-3308. PubMed ID: 32246962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.
    Langerak P; Mejia-Ramirez E; Limbo O; Russell P
    PLoS Genet; 2011 Sep; 7(9):e1002271. PubMed ID: 21931565
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
    Hopfner KP; Karcher A; Craig L; Woo TT; Carney JP; Tainer JA
    Cell; 2001 May; 105(4):473-85. PubMed ID: 11371344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA.
    Sung S; Li F; Park YB; Kim JS; Kim AK; Song OK; Kim J; Che J; Lee SE; Cho Y
    EMBO J; 2014 Oct; 33(20):2422-35. PubMed ID: 25107472
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in
    Li Y; Wang J; Zhou G; Lajeunesse M; Le N; Stawicki BN; Corcino YL; Berkner KL; Runge KW
    Genetics; 2017 May; 206(1):481-496. PubMed ID: 28292918
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The P. furiosus mre11/rad50 complex promotes 5' strand resection at a DNA double-strand break.
    Hopkins BB; Paull TT
    Cell; 2008 Oct; 135(2):250-60. PubMed ID: 18957200
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine.
    Hopfner KP; Karcher A; Shin D; Fairley C; Tainer JA; Carney JP
    J Bacteriol; 2000 Nov; 182(21):6036-41. PubMed ID: 11029422
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dimerization of the Rad50 protein is independent of the conserved hook domain.
    Cahill D; Carney JP
    Mutagenesis; 2007 Jul; 22(4):269-74. PubMed ID: 17426050
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination.
    Limbo O; Chahwan C; Yamada Y; de Bruin RA; Wittenberg C; Russell P
    Mol Cell; 2007 Oct; 28(1):134-46. PubMed ID: 17936710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
    Hopfner KP
    Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nuclease.
    Westmoreland JW; Resnick MA
    PLoS Genet; 2013 Mar; 9(3):e1003420. PubMed ID: 23555316
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination.
    Delmas S; Shunburne L; Ngo HP; Allers T
    PLoS Genet; 2009 Jul; 5(7):e1000552. PubMed ID: 19593371
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A rod conformation of the Pyrococcus furiosus Rad50 coiled coil.
    Soh YM; Basquin J; Gruber S
    Proteins; 2021 Feb; 89(2):251-255. PubMed ID: 32875643
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of the NurA-dAMP-Mn2+ complex.
    Chae J; Kim YC; Cho Y
    Nucleic Acids Res; 2012 Mar; 40(5):2258-70. PubMed ID: 22064858
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ctp1-dependent clipping and resection of DNA double-strand breaks by Mre11 endonuclease complex are not genetically separable.
    Jensen KL; Russell P
    Nucleic Acids Res; 2016 Sep; 44(17):8241-9. PubMed ID: 27325741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The rad50 signature motif: essential to ATP binding and biological function.
    Moncalian G; Lengsfeld B; Bhaskara V; Hopfner KP; Karcher A; Alden E; Tainer JA; Paull TT
    J Mol Biol; 2004 Jan; 335(4):937-51. PubMed ID: 14698290
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
    Williams RS; Dodson GE; Limbo O; Yamada Y; Williams JS; Guenther G; Classen S; Glover JN; Iwasaki H; Russell P; Tainer JA
    Cell; 2009 Oct; 139(1):87-99. PubMed ID: 19804755
    [TBL] [Abstract][Full Text] [Related]  

  • 20. S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex.
    Chen YJ; Chuang YC; Chuang CN; Cheng YH; Chang CR; Leng CH; Wang TF
    Nucleic Acids Res; 2016 Mar; 44(5):2199-213. PubMed ID: 26743002
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.