BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

386 related articles for article (PubMed ID: 18854425)

  • 1. 25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway.
    Ma Y; Xu L; Rodriguez-Agudo D; Li X; Heuman DM; Hylemon PB; Pandak WM; Ren S
    Am J Physiol Endocrinol Metab; 2008 Dec; 295(6):E1369-79. PubMed ID: 18854425
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate.
    Xu L; Bai Q; Rodriguez-Agudo D; Hylemon PB; Heuman DM; Pandak WM; Ren S
    Lipids; 2010 Sep; 45(9):821-32. PubMed ID: 20700770
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells.
    Bai Q; Xu L; Kakiyama G; Runge-Morris MA; Hylemon PB; Yin L; Pandak WM; Ren S
    Atherosclerosis; 2011 Feb; 214(2):350-6. PubMed ID: 21146170
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sulfation of 25-hydroxycholesterol regulates lipid metabolism, inflammatory responses, and cell proliferation.
    Ren S; Ning Y
    Am J Physiol Endocrinol Metab; 2014 Jan; 306(2):E123-30. PubMed ID: 24302009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytes.
    Ren S; Li X; Rodriguez-Agudo D; Gil G; Hylemon P; Pandak WM
    Biochem Biophys Res Commun; 2007 Sep; 360(4):802-8. PubMed ID: 17624300
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cholesterol metabolite, 5-cholesten-3β-25-diol-3-sulfate, promotes hepatic proliferation in mice.
    Zhang X; Bai Q; Kakiyama G; Xu L; Kim JK; Pandak WM; Ren S
    J Steroid Biochem Mol Biol; 2012 Nov; 132(3-5):262-70. PubMed ID: 22732306
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 5-cholesten-3β,25-diol 3-sulfate decreases lipid accumulation in diet-induced nonalcoholic fatty liver disease mouse model.
    Xu L; Kim JK; Bai Q; Zhang X; Kakiyama G; Min HK; Sanyal AJ; Pandak WM; Ren S
    Mol Pharmacol; 2013 Mar; 83(3):648-58. PubMed ID: 23258548
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.
    Bai Q; Zhang X; Xu L; Kakiyama G; Heuman D; Sanyal A; Pandak WM; Yin L; Xie W; Ren S
    Metabolism; 2012 Jun; 61(6):836-45. PubMed ID: 22225954
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages.
    Xu L; Shen S; Ma Y; Kim JK; Rodriguez-Agudo D; Heuman DM; Hylemon PB; Pandak WM; Ren S
    Am J Physiol Endocrinol Metab; 2012 Apr; 302(7):E788-99. PubMed ID: 22275753
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.
    Quinet EM; Savio DA; Halpern AR; Chen L; Schuster GU; Gustafsson JA; Basso MD; Nambi P
    Mol Pharmacol; 2006 Oct; 70(4):1340-9. PubMed ID: 16825483
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR.
    Wong J; Quinn CM; Brown AJ
    Biochem J; 2006 Dec; 400(3):485-91. PubMed ID: 16901265
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of SREBP-1c mRNA by differentiation and LXR ligand in human keratinocytes.
    Yokoyama A; Makishima M; Choi M; Cho Y; Nishida S; Hashimoto Y; Terui T
    J Invest Dermatol; 2009 Jun; 129(6):1395-401. PubMed ID: 19242521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line.
    Rodríguez-Acebes S; de la Cueva P; Fernández-Hernando C; Ferruelo AJ; Lasunción MA; Rawson RB; Martínez-Botas J; Gómez-Coronado D
    Biochem J; 2009 May; 420(2):305-15. PubMed ID: 19260826
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands.
    DeBose-Boyd RA; Ou J; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 2001 Feb; 98(4):1477-82. PubMed ID: 11171976
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver.
    Fernø J; Vik-Mo AO; Jassim G; Håvik B; Berge K; Skrede S; Gudbrandsen OA; Waage J; Lunder N; Mørk S; Berge RK; Jørgensen HA; Steen VM
    Psychopharmacology (Berl); 2009 Mar; 203(1):73-84. PubMed ID: 18989661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.
    Fu X; Menke JG; Chen Y; Zhou G; MacNaul KL; Wright SD; Sparrow CP; Lund EG
    J Biol Chem; 2001 Oct; 276(42):38378-87. PubMed ID: 11504730
    [TBL] [Abstract][Full Text] [Related]  

  • 17. AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells.
    Yang J; Craddock L; Hong S; Liu ZM
    J Cell Biochem; 2009 Feb; 106(3):414-26. PubMed ID: 19125418
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol.
    Beyea MM; Heslop CL; Sawyez CG; Edwards JY; Markle JG; Hegele RA; Huff MW
    J Biol Chem; 2007 Feb; 282(8):5207-16. PubMed ID: 17186944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter.
    Yoshikawa T; Shimano H; Amemiya-Kudo M; Yahagi N; Hasty AH; Matsuzaka T; Okazaki H; Tamura Y; Iizuka Y; Ohashi K; Osuga J; Harada K; Gotoda T; Kimura S; Ishibashi S; Yamada N
    Mol Cell Biol; 2001 May; 21(9):2991-3000. PubMed ID: 11287605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation.
    Rowe AH; Argmann CA; Edwards JY; Sawyez CG; Morand OH; Hegele RA; Huff MW
    Circ Res; 2003 Oct; 93(8):717-25. PubMed ID: 14512442
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.