BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 1887335)

  • 21. Site-directed mutagenesis of yeast C1-tetrahydrofolate synthase: analysis of an overlapping active site in a multifunctional enzyme.
    Barlowe CK; Williams ME; Rabinowitz JC; Appling DR
    Biochemistry; 1989 Mar; 28(5):2099-106. PubMed ID: 2541774
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice.
    Christensen KE; Malysheva OV; Carlin S; Matias F; MacFarlane AJ; Jacobs RL; Caudill MA; Rozen R
    Nutrients; 2021 Dec; 14(1):. PubMed ID: 35011003
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme.
    Barlowe CK; Appling DR
    Mol Cell Biol; 1990 Nov; 10(11):5679-87. PubMed ID: 2233711
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase from porcine liver. Location of the activities in two domains of the multifunctional polypeptide.
    Tan LU; MacKenzie RE
    Can J Biochem; 1979 Jun; 57(6):806-12. PubMed ID: 476523
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Site-directed mutagenesis of a highly conserved aspartate in the putative 10-formyl-tetrahydrofolate binding site of yeast C1-tetrahydrofolate synthase.
    Kirksey TJ; Appling DR
    Arch Biochem Biophys; 1996 Sep; 333(1):251-9. PubMed ID: 8806778
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group.
    Brody LC; Conley M; Cox C; Kirke PN; McKeever MP; Mills JL; Molloy AM; O'Leary VB; Parle-McDermott A; Scott JM; Swanson DA
    Am J Hum Genet; 2002 Nov; 71(5):1207-15. PubMed ID: 12384833
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes.
    Pawelek PD; MacKenzie RE
    Biochemistry; 1998 Jan; 37(4):1109-15. PubMed ID: 9454603
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs.
    Patel H; Pietro ED; MacKenzie RE
    J Biol Chem; 2003 May; 278(21):19436-41. PubMed ID: 12646567
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mutations in ADE3 reduce the efficiency of the omnipotent suppressor sup45-2.
    Song JM; Liebman SW
    Curr Genet; 1989 Dec; 16(5-6):315-21. PubMed ID: 2692849
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Deletion of the neural tube defect-associated gene
    Bryant JD; Sweeney SR; Sentandreu E; Shin M; Ipas H; Xhemalce B; Momb J; Tiziani S; Appling DR
    J Biol Chem; 2018 Apr; 293(16):5821-5833. PubMed ID: 29483189
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.
    MacFarlane AJ; Perry CA; McEntee MF; Lin DM; Stover PJ
    Carcinogenesis; 2011 Mar; 32(3):427-33. PubMed ID: 21156972
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A general method for generation and analysis of defined mutations in enzymes involved in a tetrahydrofolate-interconversion pathway.
    Barlowe CK; Appling DR
    Biofactors; 1989 Mar; 2(1):57-63. PubMed ID: 2679653
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mitochondrial methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetases.
    Christensen KE; Mackenzie RE
    Vitam Horm; 2008; 79():393-410. PubMed ID: 18804703
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase and formyltetrahydrofolate synthetase from porcine liver. Isolation of a dehydrogenase-cyclohydrolase fragment from the multifunctional enzyme.
    Tan LU; Mackenzie RE
    Biochim Biophys Acta; 1977 Nov; 485(1):52-9. PubMed ID: 562190
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos.
    Pike ST; Rajendra R; Artzt K; Appling DR
    J Biol Chem; 2010 Feb; 285(7):4612-20. PubMed ID: 19948730
    [TBL] [Abstract][Full Text] [Related]  

  • 36. MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice.
    Christensen KE; Deng L; Bahous RH; Jerome-Majewska LA; Rozen R
    Birth Defects Res A Clin Mol Teratol; 2015 Dec; 103(12):1031-8. PubMed ID: 26408344
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The NADP-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase is not expressed in Spodoptera frugiperda cells.
    Tremblay GB; Mejia NR; MacKenzie RE
    J Biol Chem; 1992 Apr; 267(12):8281-5. PubMed ID: 1569082
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate-cyclohydrolase-formyltetrahy dro folate synthetase. Affinity labelling of the dehydrogenase-cyclohydrolase active site.
    Smith DD; MacKenzie RE
    Biochem Biophys Res Commun; 1985 Apr; 128(1):148-54. PubMed ID: 3872659
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss.
    Parle-McDermott A; Pangilinan F; Mills JL; Signore CC; Molloy AM; Cotter A; Conley M; Cox C; Kirke PN; Scott JM; Brody LC
    Mol Hum Reprod; 2005 Jul; 11(7):477-80. PubMed ID: 16123074
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Evidence that the folate-requiring enzymes of de novo purine biosynthesis are encoded by individual mRNAs.
    Wasserman GF; Mueller WT; Benkovic SJ; Liao WS; Taylor J
    Biochemistry; 1984 Dec; 23(26):6704-10. PubMed ID: 6335666
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.