These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium. Luo C; Saxena A; Smith M; Garcia G; Radić Z; Taylor P; Doctor BP Biochemistry; 1999 Aug; 38(31):9937-47. PubMed ID: 10433700 [TBL] [Abstract][Full Text] [Related]
4. Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase. Bartling A; Worek F; Szinicz L; Thiermann H Toxicology; 2007 Apr; 233(1-3):166-72. PubMed ID: 16904809 [TBL] [Abstract][Full Text] [Related]
5. Acceleration of oxime-induced reactivation of organophosphate-inhibited fetal bovine serum acetylcholinesterase by monoquaternary and bisquaternary ligands. Luo C; Ashani Y; Doctor BP Mol Pharmacol; 1998 Apr; 53(4):718-26. PubMed ID: 9547363 [TBL] [Abstract][Full Text] [Related]
6. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds. Maxwell DM; Brecht KM; Sweeney RE Chem Biol Interact; 2013 Mar; 203(1):72-6. PubMed ID: 22982773 [TBL] [Abstract][Full Text] [Related]
7. Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study. Worek F; Herkert NM; Koller M; Aurbek N; Thiermann H Toxicol Lett; 2009 Jun; 187(2):119-23. PubMed ID: 19429253 [TBL] [Abstract][Full Text] [Related]
8. Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes. Worek F; Thiermann H; Szinicz L; Eyer P Biochem Pharmacol; 2004 Dec; 68(11):2237-48. PubMed ID: 15498514 [TBL] [Abstract][Full Text] [Related]
9. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity. Calić M; Vrdoljak AL; Radić B; Jelić D; Jun D; Kuca K; Kovarik Z Toxicology; 2006 Feb; 219(1-3):85-96. PubMed ID: 16332406 [TBL] [Abstract][Full Text] [Related]
10. Mechanism for potent reactivation ability of H oximes analyzed by reactivation kinetic studies with cholinesterases from different species. Luo C; Chambers C; Yang Y; Saxena A Chem Biol Interact; 2010 Sep; 187(1-3):185-90. PubMed ID: 20096273 [TBL] [Abstract][Full Text] [Related]
11. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship? Aurbek N; Herkert NM; Koller M; Thiermann H; Worek F Chem Biol Interact; 2010 Sep; 187(1-3):215-9. PubMed ID: 20105433 [TBL] [Abstract][Full Text] [Related]
12. Structural requirements for effective oximes--evaluation of kinetic in vitro data with phosphylated human AChE and structurally different oximes. Worek F; Wille T; Koller M; Thiermann H Chem Biol Interact; 2013 Mar; 203(1):125-8. PubMed ID: 22827894 [TBL] [Abstract][Full Text] [Related]
13. Analysis of inhibition, reactivation and aging kinetics of highly toxic organophosphorus compounds with human and pig acetylcholinesterase. Aurbek N; Thiermann H; Szinicz L; Eyer P; Worek F Toxicology; 2006 Jul; 224(1-2):91-9. PubMed ID: 16720069 [TBL] [Abstract][Full Text] [Related]
14. Unique push-pull mechanism of dealkylation in soman-inhibited cholinesterases. Viragh C; Akhmetshin R; Kovach IM; Broomfield C Biochemistry; 1997 Jul; 36(27):8243-52. PubMed ID: 9204869 [TBL] [Abstract][Full Text] [Related]
15. Testing of antidotes for organophosphorus compounds: experimental procedures and clinical reality. Eyer P; Szinicz L; Thiermann H; Worek F; Zilker T Toxicology; 2007 Apr; 233(1-3):108-19. PubMed ID: 17010492 [TBL] [Abstract][Full Text] [Related]
16. Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): a kinetic analysis. Worek F; Thiermann H Chem Biol Interact; 2011 Nov; 194(2-3):91-6. PubMed ID: 21930118 [TBL] [Abstract][Full Text] [Related]
17. Kinetic prerequisites of oximes as effective reactivators of organophosphate-inhibited acetylcholinesterase: a theoretical approach. Worek F; Aurbek N; Wille T; Eyer P; Thiermann H J Enzyme Inhib Med Chem; 2011 Jun; 26(3):303-8. PubMed ID: 20807085 [TBL] [Abstract][Full Text] [Related]
18. Effect of reversible ligands on oxime-induced reactivation of sarin- and cyclosarin-inhibited human acetylcholinesterase. Scheffel C; Thiermann H; Worek F Toxicol Lett; 2015 Feb; 232(3):557-65. PubMed ID: 25522658 [TBL] [Abstract][Full Text] [Related]
19. An in vitro comparative study on the reactivation of nerve agent-inhibited guinea pig and human acetylcholinesterases by oximes. Luo C; Tong M; Chilukuri N; Brecht K; Maxwell DM; Saxena A Biochemistry; 2007 Oct; 46(42):11771-9. PubMed ID: 17900152 [TBL] [Abstract][Full Text] [Related]
20. Comparative study of oxime-induced reactivation of erythrocyte and muscle AChE from different animal species following inhibition by sarin or paraoxon. Herkert NM; Aurbek N; Eyer P; Thiermann H; Worek F Toxicol Lett; 2010 May; 194(3):94-101. PubMed ID: 20156534 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]