BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 18931939)

  • 1. Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.
    Nathan SS; Pereira BP; Zhou YF; Gupta A; Dombrowski C; Soong R; Pho RW; Stein GS; Salto-Tellez M; Cool SM; van Wijnen AJ
    Mol Biol Rep; 2009 Jan; 36(1):153-8. PubMed ID: 18931939
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).
    Pereira BP; Zhou Y; Gupta A; Leong DT; Aung KZ; Ling L; Pho RW; Galindo M; Salto-Tellez M; Stein GS; Cool SM; van Wijnen AJ; Nathan SS
    J Cell Physiol; 2009 Dec; 221(3):778-88. PubMed ID: 19746444
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.
    Thomas DM; Johnson SA; Sims NA; Trivett MK; Slavin JL; Rubin BP; Waring P; McArthur GA; Walkley CR; Holloway AJ; Diyagama D; Grim JE; Clurman BE; Bowtell DD; Lee JS; Gutierrez GM; Piscopo DM; Carty SA; Hinds PW
    J Cell Biol; 2004 Dec; 167(5):925-34. PubMed ID: 15583032
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.
    van der Deen M; Taipaleenmäki H; Zhang Y; Teplyuk NM; Gupta A; Cinghu S; Shogren K; Maran A; Yaszemski MJ; Ling L; Cool SM; Leong DT; Dierkes C; Zustin J; Salto-Tellez M; Ito Y; Bae SC; Zielenska M; Squire JA; Lian JB; Stein JL; Zambetti GP; Jones SN; Galindo M; Hesse E; Stein GS; van Wijnen AJ
    J Biol Chem; 2013 Jul; 288(29):21307-21319. PubMed ID: 23720736
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.
    San Martin IA; Varela N; Gaete M; Villegas K; Osorio M; Tapia JC; Antonelli M; Mancilla EE; Pereira BP; Nathan SS; Lian JB; Stein JL; Stein GS; van Wijnen AJ; Galindo M
    J Cell Physiol; 2009 Dec; 221(3):560-71. PubMed ID: 19739101
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.
    Lengner CJ; Steinman HA; Gagnon J; Smith TW; Henderson JE; Kream BE; Stein GS; Lian JB; Jones SN
    J Cell Biol; 2006 Mar; 172(6):909-21. PubMed ID: 16533949
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Developmental pathways hijacked by osteosarcoma.
    Mortus JR; Zhang Y; Hughes DP
    Adv Exp Med Biol; 2014; 804():93-118. PubMed ID: 24924170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Wnt/β-Catenin Signaling Activates Expression of the Bone-Related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types.
    Vega OA; Lucero CMJ; Araya HF; Jerez S; Tapia JC; Antonelli M; Salazar-Onfray F; Las Heras F; Thaler R; Riester SM; Stein GS; van Wijnen AJ; Galindo MA
    J Cell Biochem; 2017 Nov; 118(11):3662-3674. PubMed ID: 28370561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RUNX2 expression in developing human bones and various bone tumors.
    Sugawara M; Kato N; Tsuchiya T; Motoyama T
    Pathol Int; 2011 Oct; 61(10):565-71. PubMed ID: 21951664
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RUNX2 regulates the effects of TNFalpha on proliferation and apoptosis in SaOs-2 cells.
    Olfa G; Christophe C; Philippe L; Romain S; Khaled H; Pierre H; Odile B; Jean-Christophe D
    Bone; 2010 Apr; 46(4):901-10. PubMed ID: 20053387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity.
    Ozaki T; Sugimoto H; Nakamura M; Hiraoka K; Yoda H; Sang M; Fujiwara K; Nagase H
    FEBS J; 2015 Jan; 282(1):114-28. PubMed ID: 25331851
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells.
    Makita N; Suzuki M; Asami S; Takahata R; Kohzaki D; Kobayashi S; Hakamazuka T; Hozumi N
    Gene; 2008 Apr; 413(1-2):8-17. PubMed ID: 18321663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [MicroRNA-150 inhibits osteosarcoma cell proliferation by targeting RUNX2 gene].
    Wang L; Wang W; Li J; Chen S; Zhan R
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2016 Dec; 41(12):1285-1290. PubMed ID: 28070040
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines.
    Lucero CM; Vega OA; Osorio MM; Tapia JC; Antonelli M; Stein GS; van Wijnen AJ; Galindo MA
    J Cell Physiol; 2013 Apr; 228(4):714-23. PubMed ID: 22949168
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.
    van der Deen M; Akech J; Lapointe D; Gupta S; Young DW; Montecino MA; Galindo M; Lian JB; Stein JL; Stein GS; van Wijnen AJ
    J Biol Chem; 2012 Feb; 287(7):4503-17. PubMed ID: 22158627
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The cancer-related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis.
    Villanueva F; Araya H; Briceño P; Varela N; Stevenson A; Jerez S; Tempio F; Chnaiderman J; Perez C; Villarroel M; Concha E; Khani F; Thaler R; Salazar-Onfray F; Stein GS; van Wijnen AJ; Galindo M
    J Cell Physiol; 2019 Aug; 234(8):13659-13679. PubMed ID: 30637720
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation.
    Bae JS; Gutierrez S; Narla R; Pratap J; Devados R; van Wijnen AJ; Stein JL; Stein GS; Lian JB; Javed A
    J Cell Biochem; 2007 Feb; 100(2):434-49. PubMed ID: 16927309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage.
    Berman SD; Calo E; Landman AS; Danielian PS; Miller ES; West JC; Fonhoue BD; Caron A; Bronson R; Bouxsein ML; Mukherjee S; Lees JA
    Proc Natl Acad Sci U S A; 2008 Aug; 105(33):11851-6. PubMed ID: 18697945
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BMP signaling is required for RUNX2-dependent induction of the osteoblast phenotype.
    Phimphilai M; Zhao Z; Boules H; Roca H; Franceschi RT
    J Bone Miner Res; 2006 Apr; 21(4):637-46. PubMed ID: 16598384
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional induction of the osteocalcin gene during osteoblast differentiation involves acetylation of histones h3 and h4.
    Shen J; Hovhannisyan H; Lian JB; Montecino MA; Stein GS; Stein JL; Van Wijnen AJ
    Mol Endocrinol; 2003 Apr; 17(4):743-56. PubMed ID: 12554783
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.