BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 18936059)

  • 21. Biochemical and Structural Insights into FIH-Catalysed Hydroxylation of Transient Receptor Potential Ankyrin Repeat Domains.
    Saward BG; Leissing TM; Clifton IJ; Tumber A; Timperley CM; Hopkinson RJ; Schofield CJ
    Chembiochem; 2023 Feb; 24(4):e202200576. PubMed ID: 36448355
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Host FIH-Mediated Asparaginyl Hydroxylation of Translocated
    Price C; Merchant M; Jones S; Best A; Von Dwingelo J; Lawrenz MB; Alam N; Schueler-Furman O; Kwaik YA
    Front Cell Infect Microbiol; 2017; 7():54. PubMed ID: 28321389
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
    Wilkins SE; Hyvärinen J; Chicher J; Gorman JJ; Peet DJ; Bilton RL; Koivunen P
    Int J Biochem Cell Biol; 2009 Jul; 41(7):1563-71. PubMed ID: 19401150
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
    Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
    J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
    Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
    J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
    Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
    J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells.
    Kim I; Shin SH; Lee JE; Park JW
    Oncogene; 2019 May; 38(19):3651-3666. PubMed ID: 30659265
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold.
    Kelly L; McDonough MA; Coleman ML; Ratcliffe PJ; Schofield CJ
    Mol Biosyst; 2009 Jan; 5(1):52-8. PubMed ID: 19081931
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
    Flashman E; Davies SL; Yeoh KK; Schofield CJ
    Biochem J; 2010 Mar; 427(1):135-42. PubMed ID: 20055761
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Asparagine Hydroxylation is a Reversible Post-translational Modification.
    Rodriguez J; Haydinger CD; Peet DJ; Nguyen LK; von Kriegsheim A
    Mol Cell Proteomics; 2020 Nov; 19(11):1777-1789. PubMed ID: 32759169
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.
    Lancaster DE; McDonough MA; Schofield CJ
    Biochem Soc Trans; 2004 Dec; 32(Pt 6):943-5. PubMed ID: 15506931
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
    Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
    J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.
    Dann CE; Bruick RK; Deisenhofer J
    Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15351-6. PubMed ID: 12432100
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Regulation of HIF: asparaginyl hydroxylation.
    Peet D; Linke S
    Novartis Found Symp; 2006; 272():37-49; discussion 49-53, 131-40. PubMed ID: 16686428
    [TBL] [Abstract][Full Text] [Related]  

  • 35. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.
    Lando D; Peet DJ; Gorman JJ; Whelan DA; Whitelaw ML; Bruick RK
    Genes Dev; 2002 Jun; 16(12):1466-71. PubMed ID: 12080085
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.
    Jin P; Kang J; Lee MK; Park JW
    Biochem Biophys Res Commun; 2018 May; 499(3):475-481. PubMed ID: 29580991
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways.
    Rodriguez J; Pilkington R; Garcia Munoz A; Nguyen LK; Rauch N; Kennedy S; Monsefi N; Herrero A; Taylor CT; von Kriegsheim A
    Cell Rep; 2016 Mar; 14(11):2745-60. PubMed ID: 26972000
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
    Shin DH; Li SH; Yang SW; Lee BL; Lee MK; Park JW
    FEBS J; 2009 Jul; 276(13):3470-80. PubMed ID: 19456861
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A novel HIF1AN substrate KANK3 plays a tumor-suppressive role in hepatocellular carcinoma.
    Kim I; Kang J; Gee HY; Park JW
    Cell Biol Int; 2018 Mar; 42(3):303-312. PubMed ID: 29047187
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
    Strowitzki MJ; Cummins EP; Taylor CT
    Cells; 2019 Apr; 8(5):. PubMed ID: 31035491
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.