BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

818 related articles for article (PubMed ID: 18939944)

  • 1. Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1).
    Blankenship JW; Varfolomeev E; Goncharov T; Fedorova AV; Kirkpatrick DS; Izrael-Tomasevic A; Phu L; Arnott D; Aghajan M; Zobel K; Bazan JF; Fairbrother WJ; Deshayes K; Vucic D
    Biochem J; 2009 Jan; 417(1):149-60. PubMed ID: 18939944
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.
    Varfolomeev E; Blankenship JW; Wayson SM; Fedorova AV; Kayagaki N; Garg P; Zobel K; Dynek JN; Elliott LO; Wallweber HJ; Flygare JA; Fairbrother WJ; Deshayes K; Dixit VM; Vucic D
    Cell; 2007 Nov; 131(4):669-81. PubMed ID: 18022362
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of apoptosis catch ubiquitin.
    Rajalingam K; Dikic I
    Biochem J; 2009 Jan; 417(1):e1-3. PubMed ID: 19061481
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination.
    de Almagro MC; Goncharov T; Newton K; Vucic D
    Cell Death Dis; 2015 Jun; 6(6):e1800. PubMed ID: 26111062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation.
    Varfolomeev E; Goncharov T; Fedorova AV; Dynek JN; Zobel K; Deshayes K; Fairbrother WJ; Vucic D
    J Biol Chem; 2008 Sep; 283(36):24295-9. PubMed ID: 18621737
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.
    Ndubaku C; Varfolomeev E; Wang L; Zobel K; Lau K; Elliott LO; Maurer B; Fedorova AV; Dynek JN; Koehler M; Hymowitz SG; Tsui V; Deshayes K; Fairbrother WJ; Flygare JA; Vucic D
    ACS Chem Biol; 2009 Jul; 4(7):557-66. PubMed ID: 19492850
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MAP kinase-dependent, NF-kappaB-independent regulation of inhibitor of apoptosis protein genes by TNF-alpha.
    Furusu A; Nakayama K; Xu Q; Konta T; Kitamura M
    J Cell Physiol; 2007 Mar; 210(3):703-10. PubMed ID: 17133355
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment.
    Varfolomeev E; Izrael-Tomasevic A; Yu K; Bustos D; Goncharov T; Belmont LD; Masselot A; Bakalarski CE; Kirkpatrick DS; Vucic D
    Biochem J; 2015 Feb; 466(1):45-54. PubMed ID: 25423073
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear factor-κB-inducing kinase (NIK) contains an amino-terminal inhibitor of apoptosis (IAP)-binding motif (IBM) that potentiates NIK degradation by cellular IAP1 (c-IAP1).
    Lee S; Challa-Malladi M; Bratton SB; Wright CW
    J Biol Chem; 2014 Oct; 289(44):30680-30689. PubMed ID: 25246529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TRAF2-binding BIR1 domain of c-IAP2/MALT1 fusion protein is essential for activation of NF-kappaB.
    Garrison JB; Samuel T; Reed JC
    Oncogene; 2009 Apr; 28(13):1584-93. PubMed ID: 19234489
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2.
    Li X; Yang Y; Ashwell JD
    Nature; 2002 Mar; 416(6878):345-7. PubMed ID: 11907583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells.
    Yang QH; Du C
    J Biol Chem; 2004 Apr; 279(17):16963-70. PubMed ID: 14960576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro.
    Park SM; Yoon JB; Lee TH
    FEBS Lett; 2004 May; 566(1-3):151-6. PubMed ID: 15147886
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Immunoblot Analysis of the Regulation of TNF Receptor Family-Induced NF-κB Signaling by c-IAP Proteins.
    Varfolomeev E; Goncharov T; Vucic D
    Methods Mol Biol; 2021; 2366():109-123. PubMed ID: 34236635
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of c-IAP proteins in TNF receptor family activation of NF-κB signaling.
    Varfolomeev E; Goncharov T; Vucic D
    Methods Mol Biol; 2015; 1280():269-82. PubMed ID: 25736754
    [TBL] [Abstract][Full Text] [Related]  

  • 16. c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling.
    Dynek JN; Goncharov T; Dueber EC; Fedorova AV; Izrael-Tomasevic A; Phu L; Helgason E; Fairbrother WJ; Deshayes K; Kirkpatrick DS; Vucic D
    EMBO J; 2010 Dec; 29(24):4198-209. PubMed ID: 21113135
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.
    Varfolomeev E; Wayson SM; Dixit VM; Fairbrother WJ; Vucic D
    J Biol Chem; 2006 Sep; 281(39):29022-9. PubMed ID: 16891304
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.
    Gyrd-Hansen M; Darding M; Miasari M; Santoro MM; Zender L; Xue W; Tenev T; da Fonseca PC; Zvelebil M; Bujnicki JM; Lowe S; Silke J; Meier P
    Nat Cell Biol; 2008 Nov; 10(11):1309-17. PubMed ID: 18931663
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors.
    Varfolomeev E; Goncharov T; Maecker H; Zobel K; Kömüves LG; Deshayes K; Vucic D
    Sci Signal; 2012 Mar; 5(216):ra22. PubMed ID: 22434933
    [TBL] [Abstract][Full Text] [Related]  

  • 20. OTUB1 modulates c-IAP1 stability to regulate signalling pathways.
    Goncharov T; Niessen K; de Almagro MC; Izrael-Tomasevic A; Fedorova AV; Varfolomeev E; Arnott D; Deshayes K; Kirkpatrick DS; Vucic D
    EMBO J; 2013 Apr; 32(8):1103-14. PubMed ID: 23524849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.