229 related articles for article (PubMed ID: 18948571)
1. Notch signaling is required for proliferation but not for differentiation at a well-defined beta-selection checkpoint during human T-cell development.
Taghon T; Van de Walle I; De Smet G; De Smedt M; Leclercq G; Vandekerckhove B; Plum J
Blood; 2009 Apr; 113(14):3254-63. PubMed ID: 18948571
[TBL] [Abstract][Full Text] [Related]
2. Essential role of Rap signal in pre-TCR-mediated beta-selection checkpoint in alphabeta T-cell development.
Kometani K; Moriyama M; Nakashima Y; Katayama Y; Wang SF; Yamasaki S; Saito T; Hattori M; Minato N
Blood; 2008 Dec; 112(12):4565-73. PubMed ID: 18802005
[TBL] [Abstract][Full Text] [Related]
3. Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation.
Ciofani M; Schmitt TM; Ciofani A; Michie AM; Cuburu N; Aublin A; Maryanski JL; Zúñiga-Pflücker JC
J Immunol; 2004 May; 172(9):5230-9. PubMed ID: 15100261
[TBL] [Abstract][Full Text] [Related]
4. Beta-selection is associated with the onset of CD8beta chain expression on CD4(+)CD8alphaalpha(+) pre-T cells during human intrathymic development.
Carrasco YR; Trigueros C; Ramiro AR; de Yébenes VG; Toribio ML
Blood; 1999 Nov; 94(10):3491-8. PubMed ID: 10552959
[TBL] [Abstract][Full Text] [Related]
5. Regulation of thymocyte development through CD3. II. Expression of T cell receptor beta CD3 epsilon and maturation to the CD4+8+ stage are highly correlated in individual thymocytes.
Levelt CN; Carsetti R; Eichmann K
J Exp Med; 1993 Dec; 178(6):1867-75. PubMed ID: 7504052
[TBL] [Abstract][Full Text] [Related]
6. The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.
Maillard I; Tu L; Sambandam A; Yashiro-Ohtani Y; Millholland J; Keeshan K; Shestova O; Xu L; Bhandoola A; Pear WS
J Exp Med; 2006 Oct; 203(10):2239-45. PubMed ID: 16966428
[TBL] [Abstract][Full Text] [Related]
7. Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.
Rodewald HR; Awad K; Moingeon P; D'Adamio L; Rabinowitz D; Shinkai Y; Alt FW; Reinherz EL
J Exp Med; 1993 Apr; 177(4):1079-92. PubMed ID: 8096236
[TBL] [Abstract][Full Text] [Related]
8. Early molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, and parallels other indicators of positive selection.
Kearse KP; Takahama Y; Punt JA; Sharrow SO; Singer A
J Exp Med; 1995 Jan; 181(1):193-202. PubMed ID: 7528767
[TBL] [Abstract][Full Text] [Related]
9. A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.
Barndt R; Dai MF; Zhuang Y
J Immunol; 1999 Sep; 163(6):3331-43. PubMed ID: 10477603
[TBL] [Abstract][Full Text] [Related]
10. Signal transduction via CD4, CD8, and CD28 in mature and immature thymocytes. Implications for thymic selection.
Turka LA; Linsley PS; Paine R; Schieven GL; Thompson GB; Ledbetter JA
J Immunol; 1991 Mar; 146(5):1428-36. PubMed ID: 1847160
[TBL] [Abstract][Full Text] [Related]
11. Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation.
McKean DJ; Huntoon CJ; Bell MP; Tai X; Sharrow S; Hedin KE; Conley A; Singer A
J Immunol; 2001 Mar; 166(5):3468-75. PubMed ID: 11207305
[TBL] [Abstract][Full Text] [Related]
12. Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint.
Williams JA; Hathcock KS; Klug D; Harada Y; Choudhury B; Allison JP; Abe R; Hodes RJ
J Immunol; 2005 Oct; 175(7):4199-207. PubMed ID: 16177059
[TBL] [Abstract][Full Text] [Related]
13. CD8 expression up to the double-positive CD3(low/intermediate) stage of thymic differentiation is sufficient for development of peripheral functional cytotoxic T lymphocytes.
Zhang XL; Zhao S; Borenstein SH; Liu Y; Jayabalasingham B; Chamberlain JW
J Exp Med; 2001 Sep; 194(5):685-93. PubMed ID: 11535636
[TBL] [Abstract][Full Text] [Related]
14. The requirement for pre-TCR during thymic differentiation enforces a developmental pause that is essential for V-DJβ rearrangement.
Hathcock KS; Farrington L; Ivanova I; Livak F; Selimyan R; Sen R; Williams J; Tai X; Hodes RJ
PLoS One; 2011; 6(6):e20639. PubMed ID: 21673984
[TBL] [Abstract][Full Text] [Related]
15. Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes.
Keir ME; Latchman YE; Freeman GJ; Sharpe AH
J Immunol; 2005 Dec; 175(11):7372-9. PubMed ID: 16301644
[TBL] [Abstract][Full Text] [Related]
16. Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28.
Punt JA; Osborne BA; Takahama Y; Sharrow SO; Singer A
J Exp Med; 1994 Feb; 179(2):709-13. PubMed ID: 8294878
[TBL] [Abstract][Full Text] [Related]
17. Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental program.
Levelt CN; Ehrfeld A; Eichmann K
J Exp Med; 1993 Mar; 177(3):707-16. PubMed ID: 8382254
[TBL] [Abstract][Full Text] [Related]
18. CD45 modulates T cell receptor/CD3-induced activation of human thymocytes via regulation of tyrosine phosphorylation.
Turka LA; Kanner SB; Schieven GL; Thompson CB; Ledbetter JA
Eur J Immunol; 1992 Feb; 22(2):551-7. PubMed ID: 1371471
[TBL] [Abstract][Full Text] [Related]
19. Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway.
Van Coppernolle S; Vanhee S; Verstichel G; Snauwaert S; van der Spek A; Velghe I; Sinnesael M; Heemskerk MH; Taghon T; Leclercq G; Plum J; Langerak AW; Kerre T; Vandekerckhove B
Leukemia; 2012 Jan; 26(1):127-38. PubMed ID: 22051534
[TBL] [Abstract][Full Text] [Related]
20. Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selection.
Haks MC; Pépin E; van den Brakel JH; Smeele SA; Belkowski SM; Kessels HW; Krimpenfort P; Kruisbeek AM
J Exp Med; 2002 Jul; 196(1):1-13. PubMed ID: 12093866
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
