220 related articles for article (PubMed ID: 18948576)
1. A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
Yin B; Delwel R; Valk PJ; Wallace MR; Loh ML; Shannon KM; Largaespada DA
Blood; 2009 Jan; 113(5):1075-85. PubMed ID: 18948576
[TBL] [Abstract][Full Text] [Related]
2. Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.
Chang T; Krisman K; Theobald EH; Xu J; Akutagawa J; Lauchle JO; Kogan S; Braun BS; Shannon K
J Clin Invest; 2013 Jan; 123(1):335-9. PubMed ID: 23221337
[TBL] [Abstract][Full Text] [Related]
3. Nf1 mutant mice with p19ARF gene loss develop accelerated hematopoietic disease resembling acute leukemia with a variable phenotype.
Wiesner SM; Geurts JL; Diers MD; Bergerson RJ; Hasz DE; Morgan KJ; Largaespada DA
Am J Hematol; 2011 Jul; 86(7):579-85. PubMed ID: 21681782
[TBL] [Abstract][Full Text] [Related]
4. Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency.
Sachs Z; Been RA; DeCoursin KJ; Nguyen HT; Mohd Hassan NA; Noble-Orcutt KE; Eckfeldt CE; Pomeroy EJ; Diaz-Flores E; Geurts JL; Diers MD; Hasz DE; Morgan KJ; MacMillan ML; Shannon KM; Largaespada DA; Wiesner SM
Haematologica; 2016 Oct; 101(10):1190-1199. PubMed ID: 27418650
[TBL] [Abstract][Full Text] [Related]
5. Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia.
Gurevich RM; Rosten PM; Schwieger M; Stocking C; Humphries RK
Exp Hematol; 2006 Sep; 34(9):1192-201. PubMed ID: 16939812
[TBL] [Abstract][Full Text] [Related]
6. Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.
Largaespada DA; Brannan CI; Jenkins NA; Copeland NG
Nat Genet; 1996 Feb; 12(2):137-43. PubMed ID: 8563750
[TBL] [Abstract][Full Text] [Related]
7. Role of p21(WAF1/CIP1) as an attenuator of both proliferative and drug-induced apoptotic signals in BCR-ABL-transformed hematopoietic cells.
Forster K; Obermeier A; Mitina O; Simon N; Warmuth M; Krause G; Hallek M
Ann Hematol; 2008 Mar; 87(3):183-93. PubMed ID: 17960378
[TBL] [Abstract][Full Text] [Related]
8. BCL11A expression in acute phase chronic myeloid leukemia.
Yin J; Zhang F; Tao H; Ma X; Su G; Xie X; Xu Z; Zheng Y; Liu H; He C; Mao ZJ; Wang Z; Chang W; Gale RP; Wu D; Yin B
Leuk Res; 2016 Aug; 47():88-92. PubMed ID: 27285855
[TBL] [Abstract][Full Text] [Related]
9. Bcl11a is essential for lymphoid development and negatively regulates p53.
Yu Y; Wang J; Khaled W; Burke S; Li P; Chen X; Yang W; Jenkins NA; Copeland NG; Zhang S; Liu P
J Exp Med; 2012 Dec; 209(13):2467-83. PubMed ID: 23230003
[TBL] [Abstract][Full Text] [Related]
10. Somatic SETBP1 mutations in myeloid neoplasms.
Makishima H
Int J Hematol; 2017 Jun; 105(6):732-742. PubMed ID: 28447248
[TBL] [Abstract][Full Text] [Related]
11. Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Cutts BA; Sjogren AK; Andersson KM; Wahlstrom AM; Karlsson C; Swolin B; Bergo MO
Blood; 2009 Oct; 114(17):3629-32. PubMed ID: 19710506
[TBL] [Abstract][Full Text] [Related]
12. The prognostic significance of bone marrow levels of neurofibromatosis-1 protein and ras oncogene mutations in patients with acute myeloid leukemia and myelodysplastic syndrome.
Lu D; Nounou R; Beran M; Estey E; Manshouri T; Kantarjian H; Keating MJ; Albitar M
Cancer; 2003 Jan; 97(2):441-9. PubMed ID: 12518368
[TBL] [Abstract][Full Text] [Related]
13. Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras.
Kalra R; Paderanga DC; Olson K; Shannon KM
Blood; 1994 Nov; 84(10):3435-9. PubMed ID: 7949098
[TBL] [Abstract][Full Text] [Related]
14. Mitotic recombination and compound-heterozygous mutations are predominant NF1-inactivating mechanisms in children with juvenile myelomonocytic leukemia and neurofibromatosis type 1.
Steinemann D; Arning L; Praulich I; Stuhrmann M; Hasle H; Stary J; Schlegelberger B; Niemeyer CM; Flotho C
Haematologica; 2010 Feb; 95(2):320-3. PubMed ID: 20015894
[TBL] [Abstract][Full Text] [Related]
15. Lack of the adhesion molecules P-selectin and intercellular adhesion molecule-1 accelerate the development of BCR/ABL-induced chronic myeloid leukemia-like myeloproliferative disease in mice.
Pelletier SD; Hong DS; Hu Y; Liu Y; Li S
Blood; 2004 Oct; 104(7):2163-71. PubMed ID: 15213099
[TBL] [Abstract][Full Text] [Related]
16. Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein.
Yang G; Khalaf W; van de Locht L; Jansen JH; Gao M; Thompson MA; van der Reijden BA; Gutmann DH; Delwel R; Clapp DW; Hiebert SW
Mol Cell Biol; 2005 Jul; 25(14):5869-79. PubMed ID: 15988004
[TBL] [Abstract][Full Text] [Related]
17. Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity.
Wang W; Li X; Qin X; Miao Y; Zhang Y; Li S; Yao R; Yang Y; Yu L; Zhu H; Song L; Mao S; Wang X; Chen J; Feng H; Li Y
Br J Haematol; 2023 Jul; 202(2):328-343. PubMed ID: 37144690
[TBL] [Abstract][Full Text] [Related]
18. Expression of cell cycle regulatory genes in chronic myelogenous leukemia.
Iolascon A; Della Ragione F; Giordani L; Serra A; Saglio G; Faienza MF
Haematologica; 1998 Sep; 83(9):771-7. PubMed ID: 9825572
[TBL] [Abstract][Full Text] [Related]
19. USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism.
Melo-Cardenas J; Xu Y; Wei J; Tan C; Kong S; Gao B; Montauti E; Kirsammer G; Licht JD; Yu J; Ji P; Crispino JD; Fang D
Blood; 2018 Jul; 132(4):423-434. PubMed ID: 29844011
[No Abstract] [Full Text] [Related]
20. Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia.
Gitler AD; Kong Y; Choi JK; Zhu Y; Pear WS; Epstein JA
Pediatr Res; 2004 Apr; 55(4):581-4. PubMed ID: 14739366
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]