These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 18950639)

  • 1. ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality.
    Sbrissa D; Ikonomov OC; Fenner H; Shisheva A
    J Mol Biol; 2008 Dec; 384(4):766-79. PubMed ID: 18950639
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis.
    Ikonomov OC; Sbrissa D; Fenner H; Shisheva A
    J Biol Chem; 2009 Dec; 284(51):35794-806. PubMed ID: 19840946
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines.
    Ikonomov OC; Filios C; Sbrissa D; Chen X; Shisheva A
    Biochem Biophys Res Commun; 2013 Oct; 440(2):342-7. PubMed ID: 24070605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
    Sbrissa D; Ikonomov OC; Fu Z; Ijuin T; Gruenberg J; Takenawa T; Shisheva A
    J Biol Chem; 2007 Aug; 282(33):23878-91. PubMed ID: 17556371
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder.
    Ikonomov OC; Sbrissa D; Fligger J; Delvecchio K; Shisheva A
    J Biol Chem; 2010 Aug; 285(35):26760-26764. PubMed ID: 20630877
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.
    Ikonomov OC; Sbrissa D; Ijuin T; Takenawa T; Shisheva A
    J Biol Chem; 2009 Sep; 284(36):23961-71. PubMed ID: 19578118
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes.
    Ikonomov OC; Sbrissa D; Dondapati R; Shisheva A
    Exp Cell Res; 2007 Jul; 313(11):2404-16. PubMed ID: 17475247
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Protein Complex of Neurodegeneration-related Phosphoinositide Phosphatase Sac3 and ArPIKfyve Binds the Lewy Body-associated Synphilin-1, Preventing Its Aggregation.
    Ikonomov OC; Sbrissa D; Compton LM; Kumar R; Tisdale EJ; Chen X; Shisheva A
    J Biol Chem; 2015 Nov; 290(47):28515-28529. PubMed ID: 26405034
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphoinositide phosphatase Sac3 regulates the cell surface expression of scavenger receptor A and formation of lipid droplets in macrophages.
    Morioka S; Nigorikawa K; Hazeki K; Ohmura M; Sakamoto H; Matsumura T; Takasuga S; Hazeki O
    Exp Cell Res; 2017 Aug; 357(2):252-259. PubMed ID: 28552585
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway.
    Sbrissa D; Shisheva A
    J Biol Chem; 2005 Mar; 280(9):7883-9. PubMed ID: 15546865
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry.
    Qiu S; Leung A; Bo Y; Kozak RA; Anand SP; Warkentin C; Salambanga FDR; Cui J; Kobinger G; Kobasa D; Côté M
    Virology; 2018 Jan; 513():17-28. PubMed ID: 29031163
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity.
    Sbrissa D; Ikonomov OC; Strakova J; Dondapati R; Mlak K; Deeb R; Silver R; Shisheva A
    Mol Cell Biol; 2004 Dec; 24(23):10437-47. PubMed ID: 15542851
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PIKfyve and its Lipid products in health and in sickness.
    Shisheva A
    Curr Top Microbiol Immunol; 2012; 362():127-62. PubMed ID: 23086417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization.
    Sbrissa D; Ikonomov OC; Shisheva A
    J Biol Chem; 2002 Feb; 277(8):6073-9. PubMed ID: 11706043
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.
    Sbrissa D; Ikonomov OC; Filios C; Delvecchio K; Shisheva A
    Am J Physiol Cell Physiol; 2012 Aug; 303(4):C436-46. PubMed ID: 22621786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insights into Lysosomal PI(3,5)P
    Lees JA; Li P; Kumar N; Weisman LS; Reinisch KM
    Mol Cell; 2020 Nov; 80(4):736-743.e4. PubMed ID: 33098764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes.
    Bissig C; Hurbain I; Raposo G; van Niel G
    Traffic; 2017 Nov; 18(11):747-757. PubMed ID: 28857423
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Severe Consequences of SAC3/FIG4 Phosphatase Deficiency to Phosphoinositides in Patients with Charcot-Marie-Tooth Disease Type-4J.
    Shisheva A; Sbrissa D; Hu B; Li J
    Mol Neurobiol; 2019 Dec; 56(12):8656-8667. PubMed ID: 31313076
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.
    Berwick DC; Dell GC; Welsh GI; Heesom KJ; Hers I; Fletcher LM; Cooke FT; Tavaré JM
    J Cell Sci; 2004 Dec; 117(Pt 25):5985-93. PubMed ID: 15546921
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects.
    Ikonomov OC; Sbrissa D; Mlak K; Shisheva A
    Endocrinology; 2002 Dec; 143(12):4742-54. PubMed ID: 12446602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.