BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 18951286)

  • 1. Biological activity of bis-benzimidazole derivatives on DNA topoisomerase I and HeLa, MCF7 and A431 cells.
    Alpan AS; Zencir S; Zupkó I; Coban G; Réthy B; Gunes HS; Topcu Z
    J Enzyme Inhib Med Chem; 2009 Jun; 24(3):844-9. PubMed ID: 18951286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays.
    Coban G; Zencir S; Zupkó I; Réthy B; Gunes HS; Topcu Z
    Eur J Med Chem; 2009 May; 44(5):2280-5. PubMed ID: 18692939
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles.
    Singh M; Tandon V
    Eur J Med Chem; 2011 Feb; 46(2):659-69. PubMed ID: 21186067
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1H-Benzimidazole derivatives as mammalian DNA topoisomerase I inhibitors.
    Alpan AS; Gunes HS; Topcu Z
    Acta Biochim Pol; 2007; 54(3):561-5. PubMed ID: 17823665
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and anticancer activity of some novel 2-substituted benzimidazole derivatives.
    Refaat HM
    Eur J Med Chem; 2010 Jul; 45(7):2949-56. PubMed ID: 20399544
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK; Guan J; Tachibana Y; Bastow KF; Cho SJ; Cheng HH; Cheng YC; Gurwith M; Lee KH
    J Med Chem; 1999 Jul; 42(13):2441-6. PubMed ID: 10395485
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and cytotoxic evaluation of novel 2-(4-(2,2,2-trifluoroethoxy)-3-methylpyridin-2-ylthio)-1H-benzo[d]imidazole derivatives.
    Ranganatha SR; Kavitha CV; Vinaya K; Prasanna DS; Chandrappa S; Raghavan SC; Rangappa KS
    Arch Pharm Res; 2009 Oct; 32(10):1335-43. PubMed ID: 19898794
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and in vitro cytotoxic evaluation of some thiazolylbenzimidazole derivatives.
    Luo Y; Xiao F; Qian S; Lu W; Yang B
    Eur J Med Chem; 2011 Jan; 46(1):417-22. PubMed ID: 21115212
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of benzimidazoles bearing oxadiazole nucleus as anticancer agents.
    Rashid M; Husain A; Mishra R
    Eur J Med Chem; 2012 Aug; 54():855-66. PubMed ID: 22608854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of 2-aryl-4-(benzimidazol-2-yl)-1,2-dihydro[1,2,4]triazino-[4,5-a]benzimidazol-1-one derivatives with preferential cytotoxicity against carcinoma cell lines.
    Stýskala J; Stýskalová L; Slouka J; Hajdúch M
    Eur J Med Chem; 2008 Mar; 43(3):449-55. PubMed ID: 18272255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
    Thapa P; Karki R; Thapa U; Jahng Y; Jung MJ; Nam JM; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2010 Jan; 18(1):377-86. PubMed ID: 19939682
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, antitumor activity and SAR study of novel [1,2,4]triazino[4,5-a]benzimidazole derivatives.
    El-Nassan HB
    Eur J Med Chem; 2012 Jul; 53():22-7. PubMed ID: 22542105
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of DNA topoisomerase I and II, and growth inhibition of MDA-MB-231 human breast cancer cells by bis-benzimidazole derivatives with alkylating moiety.
    Bielawski K; Wołczyński S; Bielawska A
    Pol J Pharmacol; 2004; 56(3):373-8. PubMed ID: 15215569
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of new conjugated coumarin-benzimidazole hybrids and their anticancer activity.
    Paul K; Bindal S; Luxami V
    Bioorg Med Chem Lett; 2013 Jun; 23(12):3667-72. PubMed ID: 23642480
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity.
    Kim JS; Gatto B; Yu C; Liu A; Liu LF; LaVoie EJ
    J Med Chem; 1996 Feb; 39(4):992-8. PubMed ID: 8632422
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antitumor activity of novel benzimidazole-5-carboxylic acid derivatives and their transition metal complexes as topoisomerease II inhibitors.
    Galal SA; Hegab KH; Hashem AM; Youssef NS
    Eur J Med Chem; 2010 Dec; 45(12):5685-91. PubMed ID: 20884089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel benzimidazole-pyrimidine conjugates as potent antitumor agents.
    Abdel-Mohsen HT; Ragab FA; Ramla MM; El Diwani HI
    Eur J Med Chem; 2010 Jun; 45(6):2336-44. PubMed ID: 20356655
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Gamage SA; Spicer JA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1999 Jul; 42(13):2383-93. PubMed ID: 10395479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives.
    Sondhi SM; Rani R; Singh J; Roy P; Agrawal SK; Saxena AK
    Bioorg Med Chem Lett; 2010 Apr; 20(7):2306-10. PubMed ID: 20188544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and preliminary evaluation of selected 2-aryl-5(6)-nitro- 1H-benzimidazole derivatives as potential anticancer agents.
    Romero-Castro A; León-Rivera I; Avila-Rojas LC; Navarrete-Vázquez G; Nieto-Rodríguez A
    Arch Pharm Res; 2011 Feb; 34(2):181-9. PubMed ID: 21380799
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.