BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 18951447)

  • 21. Initial Results of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer and Lynch Syndrome.
    Howarth DR; Lum SS; Esquivel P; Garberoglio CA; Senthil M; Solomon NL
    Am Surg; 2015 Oct; 81(10):941-4. PubMed ID: 26463285
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Novel germline mutations in breast cancer susceptibility genes BRCA1, BRCA2 and p53 gene in breast cancer patients from India.
    Hedau S; Jain N; Husain SA; Mandal AK; Ray G; Shahid M; Kant R; Gupta V; Shukla NK; Deo SS; Das BC
    Breast Cancer Res Treat; 2004 Nov; 88(2):177-86. PubMed ID: 15564800
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Prevalence of pathogenic variants and variants of unknown significance in patients at high risk of breast cancer: A systematic review and meta-analysis of gene-panel data.
    van Marcke C; Collard A; Vikkula M; Duhoux FP
    Crit Rev Oncol Hematol; 2018 Dec; 132():138-144. PubMed ID: 30447919
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Power of pedigree likelihood analysis in extended pedigrees to classify rare variants of uncertain significance in cancer risk genes.
    Rosenthal EA; Ranola JMO; Shirts BH
    Fam Cancer; 2017 Oct; 16(4):611-620. PubMed ID: 28534081
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A guide for functional analysis of BRCA1 variants of uncertain significance.
    Millot GA; Carvalho MA; Caputo SM; Vreeswijk MP; Brown MA; Webb M; Rouleau E; Neuhausen SL; Hansen Tv; Galli A; Brandão RD; Blok MJ; Velkova A; Couch FJ; Monteiro AN;
    Hum Mutat; 2012 Nov; 33(11):1526-37. PubMed ID: 22753008
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2.
    Goldgar DE; Easton DF; Deffenbaugh AM; Monteiro AN; Tavtigian SV; Couch FJ;
    Am J Hum Genet; 2004 Oct; 75(4):535-44. PubMed ID: 15290653
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Lynch Syndrome Limbo: Patient Understanding of Variants of Uncertain Significance.
    Solomon I; Harrington E; Hooker G; Erby L; Axilbund J; Hampel H; Semotiuk K; Blanco A; Klein WMP; Giardiello F; Leonard L
    J Genet Couns; 2017 Aug; 26(4):866-877. PubMed ID: 28127677
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Classification and Clinical Management of Variants of Uncertain Significance in High Penetrance Cancer Predisposition Genes.
    Moghadasi S; Eccles DM; Devilee P; Vreeswijk MP; van Asperen CJ
    Hum Mutat; 2016 Apr; 37(4):331-6. PubMed ID: 26777316
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The functional impact of variants of uncertain significance in BRCA2.
    Mesman RLS; Calléja FMGR; Hendriks G; Morolli B; Misovic B; Devilee P; van Asperen CJ; Vrieling H; Vreeswijk MPG
    Genet Med; 2019 Feb; 21(2):293-302. PubMed ID: 29988080
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays.
    Heinen CD; Juel Rasmussen L
    Hered Cancer Clin Pract; 2012 Jul; 10(1):9. PubMed ID: 22824075
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Invasive breast carcinomas with ATM gene variants of uncertain significance share distinct histopathologic features.
    Abdulrahman AA; Heintzelman RC; Corbman M; Garcia FU
    Breast J; 2018 May; 24(3):291-297. PubMed ID: 28986972
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Variants of uncertain significance in the era of high-throughput genome sequencing: a lesson from breast and ovary cancers.
    Federici G; Soddu S
    J Exp Clin Cancer Res; 2020 Mar; 39(1):46. PubMed ID: 32127026
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Assessment of functional effects of unclassified genetic variants.
    Couch FJ; Rasmussen LJ; Hofstra R; Monteiro AN; Greenblatt MS; de Wind N;
    Hum Mutat; 2008 Nov; 29(11):1314-26. PubMed ID: 18951449
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Genetic evidence and integration of various data sources for classifying uncertain variants into a single model.
    Goldgar DE; Easton DF; Byrnes GB; Spurdle AB; Iversen ES; Greenblatt MS;
    Hum Mutat; 2008 Nov; 29(11):1265-72. PubMed ID: 18951437
    [TBL] [Abstract][Full Text] [Related]  

  • 35. An integrative model for the comprehensive classification of BRCA1 and BRCA2 variants of uncertain clinical significance.
    Iversen ES; Lipton G; Hart SN; Lee KY; Hu C; Polley EC; Pesaran T; Yussuf A; LaDuca H; Chao E; Karam R; Goldgar DE; Couch FJ; Monteiro ANA
    NPJ Genom Med; 2022 Jun; 7(1):35. PubMed ID: 35665744
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Family Studies for Classification of Variants of Uncertain Classification: Current Laboratory Clinical Practice and a New Web-Based Educational Tool.
    Garrett LT; Hickman N; Jacobson A; Bennett RL; Amendola LM; Rosenthal EA; Shirts BH
    J Genet Couns; 2016 Dec; 25(6):1146-1156. PubMed ID: 27422780
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Factors predicting reclassification of variants of unknown significance.
    Wright M; Menon V; Taylor L; Shashidharan M; Westercamp T; Ternent CA
    Am J Surg; 2018 Dec; 216(6):1148-1154. PubMed ID: 30217367
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Management of Patients with a Genetic Variant of Unknown Significance.
    Mahon SM
    Oncol Nurs Forum; 2015 May; 42(3):316-8. PubMed ID: 25901385
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A Standardized DNA Variant Scoring System for Pathogenicity Assessments in Mendelian Disorders.
    Karbassi I; Maston GA; Love A; DiVincenzo C; Braastad CD; Elzinga CD; Bright AR; Previte D; Zhang K; Rowland CM; McCarthy M; Lapierre JL; Dubois F; Medeiros KA; Batish SD; Jones J; Liaquat K; Hoffman CA; Jaremko M; Wang Z; Sun W; Buller-Burckle A; Strom CM; Keiles SB; Higgins JJ
    Hum Mutat; 2016 Jan; 37(1):127-34. PubMed ID: 26467025
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Physician interpretation of variants of uncertain significance.
    Macklin SK; Jackson JL; Atwal PS; Hines SL
    Fam Cancer; 2019 Jan; 18(1):121-126. PubMed ID: 29721668
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.