512 related articles for article (PubMed ID: 18953358)
1. Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily.
Chatterjee A; Li Y; Zhang Y; Grove TL; Lee M; Krebs C; Booker SJ; Begley TP; Ealick SE
Nat Chem Biol; 2008 Dec; 4(12):758-65. PubMed ID: 18953358
[TBL] [Abstract][Full Text] [Related]
2. ThiC is an [Fe-S] cluster protein that requires AdoMet to generate the 4-amino-5-hydroxymethyl-2-methylpyrimidine moiety in thiamin synthesis.
Martinez-Gomez NC; Downs DM
Biochemistry; 2008 Sep; 47(35):9054-6. PubMed ID: 18686975
[TBL] [Abstract][Full Text] [Related]
3. Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase.
Fenwick MK; Mehta AP; Zhang Y; Abdelwahed SH; Begley TP; Ealick SE
Nat Commun; 2015 Mar; 6():6480. PubMed ID: 25813242
[TBL] [Abstract][Full Text] [Related]
4. A connection between iron-sulfur cluster metabolism and the biosynthesis of 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate in Salmonella enterica.
Dougherty MJ; Downs DM
Microbiology (Reading); 2006 Aug; 152(Pt 8):2345-2353. PubMed ID: 16849799
[TBL] [Abstract][Full Text] [Related]
5. High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana.
Coquille S; Roux C; Mehta A; Begley TP; Fitzpatrick TB; Thore S
J Struct Biol; 2013 Dec; 184(3):438-44. PubMed ID: 24161603
[TBL] [Abstract][Full Text] [Related]
6. Functional characterization of the HMP-P synthase of Legionella pneumophila (Lpg1565).
Paxhia MD; Swanson MS; Downs DM
Mol Microbiol; 2021 Apr; 115(4):539-553. PubMed ID: 33034117
[TBL] [Abstract][Full Text] [Related]
7. The thiamine biosynthetic enzyme ThiC catalyzes multiple turnovers and is inhibited by S-adenosylmethionine (AdoMet) metabolites.
Palmer LD; Downs DM
J Biol Chem; 2013 Oct; 288(42):30693-30699. PubMed ID: 24014032
[TBL] [Abstract][Full Text] [Related]
8. Analysis of ThiC variants in the context of the metabolic network of Salmonella enterica.
Palmer LD; Dougherty MJ; Downs DM
J Bacteriol; 2012 Nov; 194(22):6088-95. PubMed ID: 22961850
[TBL] [Abstract][Full Text] [Related]
9. Structural diversity in the AdoMet radical enzyme superfamily.
Dowling DP; Vey JL; Croft AK; Drennan CL
Biochim Biophys Acta; 2012 Nov; 1824(11):1178-95. PubMed ID: 22579873
[TBL] [Abstract][Full Text] [Related]
10. Tomato LeTHIC is an Fe-requiring HMP-P synthase involved in thiamine synthesis and regulated by multiple factors.
Zhao W; Cheng X; Huang Z; Fan H; Wu H; Ling HQ
Plant Cell Physiol; 2011 Jun; 52(6):967-82. PubMed ID: 21511719
[TBL] [Abstract][Full Text] [Related]
11. In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters.
Grove TL; Lee KH; St Clair J; Krebs C; Booker SJ
Biochemistry; 2008 Jul; 47(28):7523-38. PubMed ID: 18558715
[TBL] [Abstract][Full Text] [Related]
12. Biosynthesis of the thiamin pyrimidine: the reconstitution of a remarkable rearrangement reaction.
Lawhorn BG; Mehl RA; Begley TP
Org Biomol Chem; 2004 Sep; 2(17):2538-46. PubMed ID: 15326535
[TBL] [Abstract][Full Text] [Related]
13. ThiN as a Versatile Domain of Transcriptional Repressors and Catalytic Enzymes of Thiamine Biosynthesis.
Hwang S; Cordova B; Abdo M; Pfeiffer F; Maupin-Furlow JA
J Bacteriol; 2017 Apr; 199(7):. PubMed ID: 28115546
[TBL] [Abstract][Full Text] [Related]
14. The last piece in the vitamin B1 biosynthesis puzzle: structural and functional insight into yeast 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P) synthase.
Coquille S; Roux C; Fitzpatrick TB; Thore S
J Biol Chem; 2012 Dec; 287(50):42333-43. PubMed ID: 23048037
[TBL] [Abstract][Full Text] [Related]
15. Characterization and Reconstitution of Human Lipoyl Synthase (LIAS) Supports ISCA2 and ISCU as Primary Cluster Donors and an Ordered Mechanism of Cluster Assembly.
Hendricks AL; Wachnowsky C; Fries B; Fidai I; Cowan JA
Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33562493
[TBL] [Abstract][Full Text] [Related]
16. The A-type domain in
McCarthy EL; Rankin AN; Dill ZR; Booker SJ
J Biol Chem; 2019 Feb; 294(5):1609-1617. PubMed ID: 30538130
[TBL] [Abstract][Full Text] [Related]
17. Reaction of AdoMet with ThiC generates a backbone free radical.
Martinez-Gomez NC; Poyner RR; Mansoorabadi SO; Reed GH; Downs DM
Biochemistry; 2009 Jan; 48(2):217-9. PubMed ID: 19113839
[TBL] [Abstract][Full Text] [Related]
18. Molecular characterization of the thi3 gene involved in thiamine biosynthesis in Zea mays: cDNA sequence and enzymatic and structural properties of the recombinant bifunctional protein with 4-amino-5-hydroxymethyl-2-methylpyrimidine (phosphate) kinase and thiamine monophosphate synthase activities.
Rapala-Kozik M; Olczak M; Ostrowska K; Starosta A; Kozik A
Biochem J; 2007 Dec; 408(2):149-59. PubMed ID: 17696876
[TBL] [Abstract][Full Text] [Related]
19. Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.
Grove TL; Radle MI; Krebs C; Booker SJ
J Am Chem Soc; 2011 Dec; 133(49):19586-9. PubMed ID: 21916495
[TBL] [Abstract][Full Text] [Related]
20. Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis.
Hänzelmann P; Hernández HL; Menzel C; García-Serres R; Huynh BH; Johnson MK; Mendel RR; Schindelin H
J Biol Chem; 2004 Aug; 279(33):34721-32. PubMed ID: 15180982
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
