These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

79 related articles for article (PubMed ID: 18955029)

  • 1. Effect of mutation K85R on GSK-3beta: Molecular dynamics simulation.
    Sun H; Jiang YJ; Yu QS; Luo CC; Zou JW
    Biochem Biophys Res Commun; 2008 Dec; 377(3):962-5. PubMed ID: 18955029
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for the complete loss of GSK3beta catalytic activity due to R96 mutation investigated by molecular dynamics study.
    Zhang N; Jiang Y; Zou J; Yu Q; Zhao W
    Proteins; 2009 May; 75(3):671-81. PubMed ID: 19003984
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular dynamics simulation studies of GSK-3β ATP competitive inhibitors: understanding the factors contributing to selectivity.
    Arfeen M; Patel R; Khan T; Bharatam PV
    J Biomol Struct Dyn; 2015; 33(12):2578-93. PubMed ID: 26209183
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of kinase inactivation and nonbinding of FRATide to GSK3β due to K85M mutation: molecular dynamics simulation and normal mode analysis.
    Lu S; Jiang Y; Lv J; Zou J; Wu T
    Biopolymers; 2011 Oct; 95(10):669-81. PubMed ID: 21442609
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening.
    Zhang P; Hu HR; Huang ZH; Lei JY; Chu Y; Ye DY
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7232-6. PubMed ID: 23099099
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new protocol for predicting novel GSK-3β ATP competitive inhibitors.
    Fang J; Huang D; Zhao W; Ge H; Luo HB; Xu J
    J Chem Inf Model; 2011 Jun; 51(6):1431-8. PubMed ID: 21615159
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thienyl and phenyl alpha-halomethyl ketones: new inhibitors of glycogen synthase kinase (GSK-3beta) from a library of compound searching.
    Conde S; Pérez DI; Martínez A; Perez C; Moreno FJ
    J Med Chem; 2003 Oct; 46(22):4631-3. PubMed ID: 14561081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Homology modeling and molecular dynamics study of GSK3/SHAGGY-like kinase.
    Xiao JF; Li ZS; Sun M; Zhang Y; Sun CC
    Comput Biol Chem; 2004 Jul; 28(3):179-88. PubMed ID: 15261148
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of Li+ on GSK-3 inhibition: molecular dynamics simulation.
    Sun H; Jiang YJ; Yu QS; Luo CC; Zou JW
    J Mol Model; 2011 Feb; 17(2):377-81. PubMed ID: 20473698
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dissection of the difference between the group I metal ions in inhibiting GSK3β: a computational study.
    Lu SY; Jiang YJ; Zou JW; Wu TX
    Phys Chem Chem Phys; 2011 Apr; 13(15):7014-23. PubMed ID: 21409189
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unraveling the role of Arg4 and Arg6 in the auto-inhibition mechanism of GSK3β from molecular dynamics simulation.
    Mou L; Li M; Lu SY; Li S; Shen Q; Zhang J; Li C; Lu X
    Chem Biol Drug Des; 2014 Jun; 83(6):721-30. PubMed ID: 24444018
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elucidating substrate and inhibitor binding sites on the surface of GSK-3β and the refinement of a competitive inhibitor.
    Licht-Murava A; Plotkin B; Eisenstein M; Eldar-Finkelman H
    J Mol Biol; 2011 Apr; 408(2):366-78. PubMed ID: 21354422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis for the GSK-3beta binding affinity and selectivity against CDK-2 of 1-(4-aminofurazan-3yl)-5-dialkylaminomethyl-1H-[1,2,3] triazole-4-carboxylic acid derivatives.
    Pande V; Ramos MJ
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5129-35. PubMed ID: 16213715
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3D-QSAR and molecular docking studies on pyrazolopyrimidine derivatives as glycogen synthase kinase-3beta inhibitors.
    Dessalew N; Patel DS; Bharatam PV
    J Mol Graph Model; 2007 Mar; 25(6):885-95. PubMed ID: 17018257
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Olanzapine inhibits glycogen synthase kinase-3beta: an investigation by docking simulation and experimental validation.
    Mohammad MK; Al-Masri IM; Taha MO; Al-Ghussein MA; Alkhatib HS; Najjar S; Bustanji Y
    Eur J Pharmacol; 2008 Apr; 584(1):185-91. PubMed ID: 18295757
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.
    Twomey C; McCarthy JV
    FEBS Lett; 2006 Jul; 580(17):4015-20. PubMed ID: 16814287
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of double mutations K214/A-E215/Q of FRATide on GSK3β: insights from molecular dynamics simulation and normal mode analysis.
    Lu SY; Jiang YJ; Zou JW; Wu TX
    Amino Acids; 2012 Jul; 43(1):267-77. PubMed ID: 21912861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glycogen synthase kinase-3beta is activated by matrix metalloproteinase-2 mediated proteolysis in cardiomyoblasts.
    Kandasamy AD; Schulz R
    Cardiovasc Res; 2009 Sep; 83(4):698-706. PubMed ID: 19493954
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular modeling and molecular dynamics simulation studies of the GSK3β/ATP/substrate complex: understanding the unique P+4 primed phosphorylation specificity for GSK3β substrates.
    Lu SY; Jiang YJ; Zou JW; Wu TX
    J Chem Inf Model; 2011 May; 51(5):1025-36. PubMed ID: 21495724
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Allosteric regulation of glycogen synthase kinase 3β: a theoretical study.
    Buch I; Fishelovitch D; London N; Raveh B; Wolfson HJ; Nussinov R
    Biochemistry; 2010 Dec; 49(51):10890-901. PubMed ID: 21105670
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.