BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 18958173)

  • 1. Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM.
    Lesma E; Grande V; Ancona S; Carelli S; Di Giulio AM; Gorio A
    PLoS One; 2008; 3(10):e3558. PubMed ID: 18958173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of a lymphangioleiomyomatosis model by endonasal administration of human TSC2-/- smooth muscle cells in mice.
    Lesma E; Eloisa C; Isaia E; Grande V; Ancona S; Orpianesi E; Di Giulio AM; Gorio A
    Am J Pathol; 2012 Sep; 181(3):947-60. PubMed ID: 22770663
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chromatin remodeling by rosuvastatin normalizes TSC2-/meth cell phenotype through the expression of tuberin.
    Lesma E; Ancona S; Orpianesi E; Grande V; Di Giulio AM; Gorio A
    J Pharmacol Exp Ther; 2013 May; 345(2):180-8. PubMed ID: 23426956
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isolation and growth of smooth muscle-like cells derived from tuberous sclerosis complex-2 human renal angiomyolipoma: epidermal growth factor is the required growth factor.
    Lesma E; Grande V; Carelli S; Brancaccio D; Canevini MP; Alfano RM; Coggi G; Di Giulio AM; Gorio A
    Am J Pathol; 2005 Oct; 167(4):1093-103. PubMed ID: 16192644
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TSC2 epigenetic defect in primary LAM cells. Evidence of an anchorage-independent survival.
    Lesma E; Ancona S; Sirchia SM; Orpianesi E; Grande V; Colapietro P; Chiaramonte E; Di Giulio AM; Gorio A
    J Cell Mol Med; 2014 May; 18(5):766-79. PubMed ID: 24606538
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells.
    Lesma E; Sirchia SM; Ancona S; Carelli S; Bosari S; Ghelma F; Montanari E; Di Giulio AM; Gorio A
    Am J Pathol; 2009 Jun; 174(6):2150-9. PubMed ID: 19443708
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure.
    Lin CY; Hsu SC; Lee HS; Lin SH; Tsai CS; Huang SM; Shih CC; Hsu YJ
    J Vasc Surg; 2013 Feb; 57(2):475-85. PubMed ID: 23265586
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-EGFR antibody reduces lung nodules by inhibition of EGFR-pathway in a model of lymphangioleiomyomatosis.
    Lesma E; Chiaramonte E; Ancona S; Orpianesi E; Di Giulio AM; Gorio A
    Biomed Res Int; 2015; 2015():315240. PubMed ID: 25699271
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis.
    Sato T; Seyama K; Fujii H; Maruyama H; Setoguchi Y; Iwakami S; Fukuchi Y; Hino O
    J Hum Genet; 2002; 47(1):20-8. PubMed ID: 11829138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease.
    Astrinidis A; Henske EP
    Oncogene; 2005 Nov; 24(50):7475-81. PubMed ID: 16288294
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multifocal micronodular pneumocyte hyperplasia and lymphangioleiomyomatosis in tuberous sclerosis with a TSC2 gene.
    Maruyama H; Seyama K; Sobajima J; Kitamura K; Sobajima T; Fukuda T; Hamada K; Tsutsumi M; Hino O; Konishi Y
    Mod Pathol; 2001 Jun; 14(6):609-14. PubMed ID: 11406664
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis.
    Li C; Zhang E; Sun Y; Lee PS; Zhan Y; Guo Y; Osorio JC; Rosas IO; Xu KF; Kwiatkowski DJ; Yu JJ
    PLoS One; 2014; 9(10):e104809. PubMed ID: 25347447
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Survivin expression in tuberous sclerosis complex cells.
    Carelli S; Lesma E; Paratore S; Grande V; Zadra G; Bosari S; Di Giulio AM; Gorio A
    Mol Med; 2007; 13(3-4):166-77. PubMed ID: 17592551
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer.
    Ma L; Teruya-Feldstein J; Bonner P; Bernardi R; Franz DN; Witte D; Cordon-Cardo C; Pandolfi PP
    Cancer Res; 2007 Aug; 67(15):7106-12. PubMed ID: 17671177
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: a potential treatment for lymphangioleiomyomatosis.
    Makovski V; Haklai R; Kloog Y
    Int J Cancer; 2012 Mar; 130(6):1420-9. PubMed ID: 21500191
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.
    Ma L; Chen Z; Erdjument-Bromage H; Tempst P; Pandolfi PP
    Cell; 2005 Apr; 121(2):179-93. PubMed ID: 15851026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective inhibition of growth of tuberous sclerosis complex 2 null cells by atorvastatin is associated with impaired Rheb and Rho GTPase function and reduced mTOR/S6 kinase activity.
    Finlay GA; Malhowski AJ; Liu Y; Fanburg BL; Kwiatkowski DJ; Toksoz D
    Cancer Res; 2007 Oct; 67(20):9878-86. PubMed ID: 17942919
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells.
    Uhlmann EJ; Apicelli AJ; Baldwin RL; Burke SP; Bajenaru ML; Onda H; Kwiatkowski D; Gutmann DH
    Oncogene; 2002 Jun; 21(25):4050-9. PubMed ID: 12037687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chromosome 16 loss of heterozygosity in tuberous sclerosis and sporadic lymphangiomyomatosis.
    Yu J; Astrinidis A; Henske EP
    Am J Respir Crit Care Med; 2001 Oct; 164(8 Pt 1):1537-40. PubMed ID: 11704609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metastasis of benign tumor cells in tuberous sclerosis complex.
    Henske EP
    Genes Chromosomes Cancer; 2003 Dec; 38(4):376-81. PubMed ID: 14566858
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.