BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 18959765)

  • 1. ATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.
    Oza SL; Chen S; Wyllie S; Coward JK; Fairlamb AH
    FEBS J; 2008 Nov; 275(21):5408-21. PubMed ID: 18959765
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.
    Oza SL; Tetaud E; Ariyanayagam MR; Warnon SS; Fairlamb AH
    J Biol Chem; 2002 Sep; 277(39):35853-61. PubMed ID: 12121990
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trypanothione biosynthesis in Leishmania major.
    Oza SL; Shaw MP; Wyllie S; Fairlamb AH
    Mol Biochem Parasitol; 2005 Jan; 139(1):107-16. PubMed ID: 15610825
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Properties of trypanothione synthetase from Trypanosoma brucei.
    Oza SL; Ariyanayagam MR; Aitcheson N; Fairlamb AH
    Mol Biochem Parasitol; 2003 Sep; 131(1):25-33. PubMed ID: 12967709
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Convenient isolation and kinetic mechanism of glutathionylspermidine synthetase from Crithidia fasciculata.
    Koenig K; Menge U; Kiess M; Wray V; Flohé L
    J Biol Chem; 1997 May; 272(18):11908-15. PubMed ID: 9115252
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trypanothione synthesis in crithidia revisited.
    Comini M; Menge U; Wissing J; Flohé L
    J Biol Chem; 2005 Feb; 280(8):6850-60. PubMed ID: 15537651
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata.
    Oza SL; Ariyanayagam MR; Fairlamb AH
    Biochem J; 2002 Jun; 364(Pt 3):679-86. PubMed ID: 12049631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biosynthesis of the trypanosomatid metabolite trypanothione: purification and characterization of trypanothione synthetase from Crithidia fasciculata.
    Henderson GB; Yamaguchi M; Novoa L; Fairlamb AH; Cerami A
    Biochemistry; 1990 Apr; 29(16):3924-9. PubMed ID: 2354163
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata.
    Tetaud E; Manai F; Barrett MP; Nadeau K; Walsh CT; Fairlamb AH
    J Biol Chem; 1998 Jul; 273(31):19383-90. PubMed ID: 9677355
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the peptide substrate specificity of glutathionylspermidine synthetase from Crithidia fasciculata.
    De Craecker S; Verbruggen C; Rajan PK; Smith K; Haemers A; Fairlamb AH
    Mol Biochem Parasitol; 1997 Jan; 84(1):25-32. PubMed ID: 9041518
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aldehyde and phosphinate analogs of glutathione and glutathionylspermidine: potent, selective binding inhibitors of the E. coli bifunctional glutathionylspermidine synthetase/amidase.
    Lin CH; Chen S; Kwon DS; Coward JK; Walsh CT
    Chem Biol; 1997 Nov; 4(11):859-66. PubMed ID: 9384533
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase.
    Pai CH; Chiang BY; Ko TP; Chou CC; Chong CM; Yen FJ; Chen S; Coward JK; Wang AH; Lin CH
    EMBO J; 2006 Dec; 25(24):5970-82. PubMed ID: 17124497
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum.
    Sousa AF; Gomes-Alves AG; Benítez D; Comini MA; Flohé L; Jaeger T; Passos J; Stuhlmann F; Tomás AM; Castro H
    Free Radic Biol Med; 2014 Aug; 73():229-38. PubMed ID: 24853758
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biochemical evaluation of phosphonate and phosphonamidate analogs of glutathionylspermidine as inhibitors of glutathionylspermidine synthetase/amidase from Escherichia coli.
    Chen S; Lin CH; Kwon DS; Walsh CT; Coward JK
    J Med Chem; 1997 Nov; 40(23):3842-50. PubMed ID: 9371250
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preparative enzymatic synthesis of trypanothione and trypanothione analogues.
    Comini MA; Dirdjaja N; Kaschel M; Krauth-Siegel RL
    Int J Parasitol; 2009 Aug; 39(10):1059-62. PubMed ID: 19477177
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The biosynthesis of trypanothione and N1-glutathionylspermidine in Crithidia fasciculata.
    Fairlamb AH; Henderson GB; Cerami A
    Mol Biochem Parasitol; 1986 Dec; 21(3):247-57. PubMed ID: 3807945
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis.
    Ravaschino EL; Docampo R; Rodriguez JB
    J Med Chem; 2006 Jan; 49(1):426-35. PubMed ID: 16392828
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling.
    Leroux AE; Haanstra JR; Bakker BM; Krauth-Siegel RL
    J Biol Chem; 2013 Aug; 288(33):23751-64. PubMed ID: 23814051
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Purification of glutathionylspermidine and trypanothione synthetases from Crithidia fasciculata.
    Smith K; Nadeau K; Bradley M; Walsh C; Fairlamb AH
    Protein Sci; 1992 Jul; 1(7):874-83. PubMed ID: 1304372
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular dynamics reveal binding mode of glutathionylspermidine by trypanothione synthetase.
    Koch O; Cappel D; Nocker M; Jäger T; Flohé L; Sotriffer CA; Selzer PM
    PLoS One; 2013; 8(2):e56788. PubMed ID: 23451087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.