154 related articles for article (PubMed ID: 18971327)
1. Mechanism of thermal decomposition of carbamoyl phosphate and its stabilization by aspartate and ornithine transcarbamoylases.
Wang Q; Xia J; Guallar V; Krilov G; Kantrowitz ER
Proc Natl Acad Sci U S A; 2008 Nov; 105(44):16918-23. PubMed ID: 18971327
[TBL] [Abstract][Full Text] [Related]
2. The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.
Sankaranarayanan R; Cherney MM; Cherney LT; Garen CR; Moradian F; James MN
J Mol Biol; 2008 Jan; 375(4):1052-63. PubMed ID: 18062991
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of human ornithine transcarbamylase complexed with carbamoyl phosphate and L-norvaline at 1.9 A resolution.
Shi D; Morizono H; Aoyagi M; Tuchman M; Allewell NM
Proteins; 2000 Jun; 39(4):271-7. PubMed ID: 10813810
[TBL] [Abstract][Full Text] [Related]
4. Structural similarity between ornithine and aspartate transcarbamoylases of Escherichia coli: characterization of the active site and evidence for an interdomain carboxy-terminal helix in ornithine transcarbamoylase.
Murata LB; Schachman HK
Protein Sci; 1996 Apr; 5(4):709-18. PubMed ID: 8845761
[TBL] [Abstract][Full Text] [Related]
5. Structure of the catalytic chain of Methanococcus jannaschii aspartate transcarbamoylase in a hexagonal crystal form: insights into the path of carbamoyl phosphate to the active site of the enzyme.
Vitali J; Singh AK; Soares AS; Colaneri MJ
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 May; 68(Pt 5):527-34. PubMed ID: 22691781
[TBL] [Abstract][Full Text] [Related]
6. Carbamoyl phosphate biosynthesis and partition in pyrimidine and arginine pathways of Escherichia coli. In situ properties of carbamoyl-phosphate synthase, ornithine transcarbamylase and aspartate transcarbamylase in permeabilized cells.
Robin JP; Penverne B; Hervé G
Eur J Biochem; 1989 Aug; 183(3):519-28. PubMed ID: 2673777
[TBL] [Abstract][Full Text] [Related]
7. Protonation of arginine 57 of Escherichia coli ornithine transcarbamoylase regulates substrate binding and turnover.
Goldsmith JO; Kuo LC
J Biol Chem; 1993 Sep; 268(25):18485-90. PubMed ID: 8395503
[TBL] [Abstract][Full Text] [Related]
8. Probing remote residues important for catalysis in Escherichia coli ornithine transcarbamoylase.
Ngu L; Winters JN; Nguyen K; Ramos KE; DeLateur NA; Makowski L; Whitford PC; Ondrechen MJ; Beuning PJ
PLoS One; 2020; 15(2):e0228487. PubMed ID: 32027716
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum.
Lunev S; Bosch SS; Batista Fde A; Wrenger C; Groves MR
Acta Crystallogr F Struct Biol Commun; 2016 Jul; 72(Pt 7):523-33. PubMed ID: 27380369
[TBL] [Abstract][Full Text] [Related]
10. T-state active site of aspartate transcarbamylase: crystal structure of the carbamyl phosphate and L-alanosine ligated enzyme.
Huang J; Lipscomb WN
Biochemistry; 2006 Jan; 45(2):346-52. PubMed ID: 16401065
[TBL] [Abstract][Full Text] [Related]
11. Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study.
Stebbins JW; Robertson DE; Roberts MF; Stevens RC; Lipscomb WN; Kantrowitz ER
Protein Sci; 1992 Nov; 1(11):1435-46. PubMed ID: 1303763
[TBL] [Abstract][Full Text] [Related]
12. Metabolic channelling of carbamoyl phosphate in the hyperthermophilic archaeon Pyrococcus furiosus: dynamic enzyme-enzyme interactions involved in the formation of the channelling complex.
Massant J; Glansdorff N
Biochem Soc Trans; 2004 Apr; 32(Pt 2):306-9. PubMed ID: 15046596
[TBL] [Abstract][Full Text] [Related]
13. A 70-amino acid zinc-binding polypeptide fragment from the regulatory chain of aspartate transcarbamoylase causes marked changes in the kinetic mechanism of the catalytic trimer.
Zhou BB; Waldrop GL; Lum L; Schachman HK
Protein Sci; 1994 Jun; 3(6):967-74. PubMed ID: 8069226
[TBL] [Abstract][Full Text] [Related]
14. 1.85-A resolution crystal structure of human ornithine transcarbamoylase complexed with N-phosphonacetyl-L-ornithine. Catalytic mechanism and correlation with inherited deficiency.
Shi D; Morizono H; Ha Y; Aoyagi M; Tuchman M; Allewell NM
J Biol Chem; 1998 Dec; 273(51):34247-54. PubMed ID: 9852088
[TBL] [Abstract][Full Text] [Related]
15. Substrate specificity and protonation state of Escherichia coli ornithine transcarbamoylase as determined by pH studies. Binding of carbamoyl phosphate.
Zambidis I; Kuo LC
J Biol Chem; 1990 Feb; 265(5):2620-3. PubMed ID: 2154453
[TBL] [Abstract][Full Text] [Related]
16. Products in the T-state of aspartate transcarbamylase: crystal structure of the phosphate and N-carbamyl-L-aspartate ligated enzyme.
Huang J; Lipscomb WN
Biochemistry; 2004 Jun; 43(21):6422-6. PubMed ID: 15157076
[TBL] [Abstract][Full Text] [Related]
17. Apparent cooperativity for carbamoylphosphate in Escherichia coli aspartate transcarbamoylase only reflects cooperativity for aspartate.
England P; Leconte C; Tauc P; Hervé G
Eur J Biochem; 1994 Jun; 222(3):775-80. PubMed ID: 8026491
[TBL] [Abstract][Full Text] [Related]
18. Reconstruction of an enzyme by domain substitution effectively switches substrate specificity.
Houghton JE; O'Donovan GA; Wild JR
Nature; 1989 Mar; 338(6211):172-4. PubMed ID: 2918938
[TBL] [Abstract][Full Text] [Related]
19. Human ornithine transcarbamylase: crystallographic insights into substrate recognition and conformational changes.
Shi D; Morizono H; Yu X; Tong L; Allewell NM; Tuchman M
Biochem J; 2001 Mar; 354(Pt 3):501-9. PubMed ID: 11237854
[TBL] [Abstract][Full Text] [Related]
20. Utilization of conformational flexibility in enzyme action-linkage between binding, isomerization, and catalysis.
Goldsmith JO; Kuo LC
J Biol Chem; 1993 Sep; 268(25):18481-4. PubMed ID: 8360150
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]