BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

401 related articles for article (PubMed ID: 18973804)

  • 1. Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element.
    Chowdhury I; Mo Y; Gao L; Kazi A; Fisher AB; Feinstein SI
    Free Radic Biol Med; 2009 Jan; 46(2):146-53. PubMed ID: 18973804
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2.
    Singh A; Rangasamy T; Thimmulappa RK; Lee H; Osburn WO; Brigelius-Flohé R; Kensler TW; Yamamoto M; Biswal S
    Am J Respir Cell Mol Biol; 2006 Dec; 35(6):639-50. PubMed ID: 16794261
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress.
    Kubo E; Chhunchha B; Singh P; Sasaki H; Singh DP
    Sci Rep; 2017 Oct; 7(1):14130. PubMed ID: 29074861
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Keratinocyte growth factor and glucocorticoid induction of human peroxiredoxin 6 gene expression occur by independent mechanisms that are synergistic.
    Chowdhury I; Fisher AB; Christofidou-Solomidou M; Gao L; Tao JQ; Sorokina EM; Lien YC; Bates SR; Feinstein SI
    Antioxid Redox Signal; 2014 Jan; 20(3):391-402. PubMed ID: 23815338
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements.
    Arinze IJ; Kawai Y
    J Biol Chem; 2005 Mar; 280(11):9786-95. PubMed ID: 15640523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress.
    Habib E; Linher-Melville K; Lin HX; Singh G
    Redox Biol; 2015 Aug; 5():33-42. PubMed ID: 25827424
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.
    Sankaranarayanan K; Jaiswal AK
    J Biol Chem; 2004 Dec; 279(49):50810-7. PubMed ID: 15385560
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Long-acting genipin derivative protects retinal ganglion cells from oxidative stress models in vitro and in vivo through the Nrf2/antioxidant response element signaling pathway.
    Koriyama Y; Chiba K; Yamazaki M; Suzuki H; Muramoto K; Kato S
    J Neurochem; 2010 Oct; 115(1):79-91. PubMed ID: 20681953
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
    Sun Z; Zhang S; Chan JY; Zhang DD
    Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of the Nrf2/ARE pathway via S-alkylation of cysteine 151 in the chemopreventive agent-sensor Keap1 protein by falcarindiol, a conjugated diacetylene compound.
    Ohnuma T; Nakayama S; Anan E; Nishiyama T; Ogura K; Hiratsuka A
    Toxicol Appl Pharmacol; 2010 Apr; 244(1):27-36. PubMed ID: 20026152
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin.
    Tanigawa S; Fujii M; Hou DX
    Free Radic Biol Med; 2007 Jun; 42(11):1690-703. PubMed ID: 17462537
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death.
    Yao JW; Liu J; Kong XZ; Zhang SG; Wang XH; Yu M; Zhan YQ; Li W; Xu WX; Tang LJ; Ge CH; Wang L; Li CY; Yang XM
    Toxicol Appl Pharmacol; 2012 Mar; 259(2):227-35. PubMed ID: 22245129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants.
    Dhakshinamoorthy S; Jain AK; Bloom DA; Jaiswal AK
    J Biol Chem; 2005 Apr; 280(17):16891-900. PubMed ID: 15734732
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of the negative regulator of Nrf2, Keap1: a historical overview.
    Itoh K; Mimura J; Yamamoto M
    Antioxid Redox Signal; 2010 Dec; 13(11):1665-78. PubMed ID: 20446768
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of aldo-keto reductases as NRF2-target marker genes in human cells.
    Jung KA; Choi BH; Nam CW; Song M; Kim ST; Lee JY; Kwak MK
    Toxicol Lett; 2013 Mar; 218(1):39-49. PubMed ID: 23305850
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model.
    Shimozono R; Asaoka Y; Yoshizawa Y; Aoki T; Noda H; Yamada M; Kaino M; Mochizuki H
    Mol Pharmacol; 2013 Jul; 84(1):62-70. PubMed ID: 23592516
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression.
    Kaspar JW; Jaiswal AK
    J Biol Chem; 2010 Jan; 285(1):153-62. PubMed ID: 19897490
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage.
    Cao TT; Ma L; Kandpal G; Warren L; Hess JF; Seabrook GR
    J Neurochem; 2005 Oct; 95(2):406-17. PubMed ID: 16092930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.
    Blake DJ; Singh A; Kombairaju P; Malhotra D; Mariani TJ; Tuder RM; Gabrielson E; Biswal S
    Am J Respir Cell Mol Biol; 2010 May; 42(5):524-36. PubMed ID: 19520915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology.
    Kim YJ; Ahn JY; Liang P; Ip C; Zhang Y; Park YM
    Cancer Res; 2007 Jan; 67(2):546-54. PubMed ID: 17234762
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.