351 related articles for article (PubMed ID: 18974095)
1. Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling.
Stevens C; Lin Y; Harrison B; Burch L; Ridgway RA; Sansom O; Hupp T
J Biol Chem; 2009 Jan; 284(1):334-344. PubMed ID: 18974095
[TBL] [Abstract][Full Text] [Related]
2. Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
Lin Y; Henderson P; Pettersson S; Satsangi J; Hupp T; Stevens C
FEBS J; 2011 Jan; 278(2):354-70. PubMed ID: 21134130
[TBL] [Abstract][Full Text] [Related]
3. DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.
Harrison B; Kraus M; Burch L; Stevens C; Craig A; Gordon-Weeks P; Hupp TR
J Biol Chem; 2008 Apr; 283(15):9999-10014. PubMed ID: 18195017
[TBL] [Abstract][Full Text] [Related]
4. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.
Zhang HH; Huang J; Düvel K; Boback B; Wu S; Squillace RM; Wu CL; Manning BD
PLoS One; 2009 Jul; 4(7):e6189. PubMed ID: 19593385
[TBL] [Abstract][Full Text] [Related]
5. Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors.
Huang J; Wu S; Wu CL; Manning BD
Cancer Res; 2009 Aug; 69(15):6107-14. PubMed ID: 19602587
[TBL] [Abstract][Full Text] [Related]
6. Tumor suppressors TSC1 and TSC2 differentially modulate actin cytoskeleton and motility of mouse embryonic fibroblasts.
Goncharova EA; James ML; Kudryashova TV; Goncharov DA; Krymskaya VP
PLoS One; 2014; 9(10):e111476. PubMed ID: 25360538
[TBL] [Abstract][Full Text] [Related]
7. ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling.
Winter JN; Jefferson LS; Kimball SR
Am J Physiol Cell Physiol; 2011 May; 300(5):C1172-80. PubMed ID: 21289294
[TBL] [Abstract][Full Text] [Related]
8. The TSC1-TSC2 complex is required for proper activation of mTOR complex 2.
Huang J; Dibble CC; Matsuzaki M; Manning BD
Mol Cell Biol; 2008 Jun; 28(12):4104-15. PubMed ID: 18411301
[TBL] [Abstract][Full Text] [Related]
9. Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
Wolff NC; Vega-Rubin-de-Celis S; Xie XJ; Castrillon DH; Kabbani W; Brugarolas J
Mol Cell Biol; 2011 May; 31(9):1870-84. PubMed ID: 21383064
[TBL] [Abstract][Full Text] [Related]
10. Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.
Moore SF; Hunter RW; Hers I
J Thromb Haemost; 2014 May; 12(5):748-60. PubMed ID: 24612393
[TBL] [Abstract][Full Text] [Related]
11. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.
Tan SH; Shui G; Zhou J; Shi Y; Huang J; Xia D; Wenk MR; Shen HM
Autophagy; 2014 Feb; 10(2):226-42. PubMed ID: 24296537
[TBL] [Abstract][Full Text] [Related]
12. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
Xie J; Ponuwei GA; Moore CE; Willars GB; Tee AR; Herbert TP
Cell Signal; 2011 Dec; 23(12):1927-35. PubMed ID: 21763421
[TBL] [Abstract][Full Text] [Related]
13. mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.
Bhaskar PT; Nogueira V; Patra KC; Jeon SM; Park Y; Robey RB; Hay N
Mol Cell Biol; 2009 Sep; 29(18):5136-47. PubMed ID: 19620286
[TBL] [Abstract][Full Text] [Related]
14. Novel insights into DAPK autophagic signalling using peptide aptamer combinatorial protein-interaction screens.
Stevens C; Hupp TR
Autophagy; 2008 May; 4(4):531-3. PubMed ID: 18376136
[TBL] [Abstract][Full Text] [Related]
15. The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
Kathage B; Gehlert S; Ulbricht A; Lüdecke L; Tapia VE; Orfanos Z; Wenzel D; Bloch W; Volkmer R; Fleischmann BK; Fürst DO; Höhfeld J
Biochim Biophys Acta Mol Cell Res; 2017 Jan; 1864(1):62-75. PubMed ID: 27756573
[TBL] [Abstract][Full Text] [Related]
16. Regulation of mTORC1 signaling by pH.
Balgi AD; Diering GH; Donohue E; Lam KK; Fonseca BD; Zimmerman C; Numata M; Roberge M
PLoS One; 2011; 6(6):e21549. PubMed ID: 21738705
[TBL] [Abstract][Full Text] [Related]
17. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
Tripathi DN; Chowdhury R; Trudel LJ; Tee AR; Slack RS; Walker CL; Wogan GN
Proc Natl Acad Sci U S A; 2013 Aug; 110(32):E2950-7. PubMed ID: 23878245
[TBL] [Abstract][Full Text] [Related]
18. Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling.
Miyazaki M; McCarthy JJ; Fedele MJ; Esser KA
J Physiol; 2011 Apr; 589(Pt 7):1831-46. PubMed ID: 21300751
[TBL] [Abstract][Full Text] [Related]
19. mTORC2 is required for proliferation and survival of TSC2-null cells.
Goncharova EA; Goncharov DA; Li H; Pimtong W; Lu S; Khavin I; Krymskaya VP
Mol Cell Biol; 2011 Jun; 31(12):2484-98. PubMed ID: 21482669
[TBL] [Abstract][Full Text] [Related]
20. Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner.
Bilanges B; Argonza-Barrett R; Kolesnichenko M; Skinner C; Nair M; Chen M; Stokoe D
Mol Cell Biol; 2007 Aug; 27(16):5746-64. PubMed ID: 17562867
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
