These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

383 related articles for article (PubMed ID: 18974783)

  • 1. Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
    Chen J; Futami K; Petillo D; Peng J; Wang P; Knol J; Li Y; Khoo SK; Huang D; Qian CN; Zhao P; Dykema K; Zhang R; Cao B; Yang XJ; Furge K; Williams BO; Teh BT
    PLoS One; 2008; 3(10):e3581. PubMed ID: 18974783
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein.
    Takagi Y; Kobayashi T; Shiono M; Wang L; Piao X; Sun G; Zhang D; Abe M; Hagiwara Y; Takahashi K; Hino O
    Oncogene; 2008 Sep; 27(40):5339-47. PubMed ID: 18663353
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
    Baba M; Furihata M; Hong SB; Tessarollo L; Haines DC; Southon E; Patel V; Igarashi P; Alvord WG; Leighty R; Yao M; Bernardo M; Ileva L; Choyke P; Warren MB; Zbar B; Linehan WM; Schmidt LS
    J Natl Cancer Inst; 2008 Jan; 100(2):140-54. PubMed ID: 18182616
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
    Hudon V; Sabourin S; Dydensborg AB; Kottis V; Ghazi A; Paquet M; Crosby K; Pomerleau V; Uetani N; Pause A
    J Med Genet; 2010 Mar; 47(3):182-9. PubMed ID: 19843504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Investigation of the Birt-Hogg-Dube tumour suppressor gene (FLCN) in familial and sporadic colorectal cancer.
    Nahorski MS; Lim DH; Martin L; Gille JJ; McKay K; Rehal PK; Ploeger HM; van Steensel M; Tomlinson IP; Latif F; Menko FH; Maher ER
    J Med Genet; 2010 Jun; 47(6):385-90. PubMed ID: 20522427
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Birt-Hogg-Dubé syndrome].
    Rehfeld A; van Steensel MA; Friis-Hansen L
    Ugeskr Laeger; 2010 Jul; 172(29):2085-90. PubMed ID: 20633341
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
    Wu M; Si S; Li Y; Schoen S; Xiao GQ; Li X; Teh BT; Wu G; Chen J
    Oncotarget; 2015 Oct; 6(32):32761-73. PubMed ID: 26418749
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of BHD in sporadic renal tumors.
    Khoo SK; Kahnoski K; Sugimura J; Petillo D; Chen J; Shockley K; Ludlow J; Knapp R; Giraud S; Richard S; Nordenskjöld M; Teh BT
    Cancer Res; 2003 Aug; 63(15):4583-7. PubMed ID: 12907635
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A new locus-specific database (LSDB) for mutations in the folliculin (FLCN) gene.
    Lim DH; Rehal PK; Nahorski MS; Macdonald F; Claessens T; Van Geel M; Gijezen L; Gille JJ; Giraud S; Richard S; van Steensel M; Menko FH; Maher ER
    Hum Mutat; 2010 Jan; 31(1):E1043-51. PubMed ID: 19802896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN).
    Lu X; Boora U; Seabra L; Rabai EM; Fenton J; Reiman A; Nagy Z; Maher ER
    Oncogene; 2014 Feb; 33(8):956-65. PubMed ID: 23416984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disruption of tubular Flcn expression as a mouse model for renal tumor induction.
    Chen J; Huang D; Rubera I; Futami K; Wang P; Zickert P; Khoo SK; Dykema K; Zhao P; Petillo D; Cao B; Zhang Z; Si S; Schoen SR; Yang XJ; Zhou M; Xiao GQ; Wu G; Nordenskjöld M; Tauc M; Williams BO; Furge KA; Teh BT
    Kidney Int; 2015 Nov; 88(5):1057-69. PubMed ID: 26083655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression.
    Nagashima K; Fukushima H; Shimizu K; Yamada A; Hidaka M; Hasumi H; Ikebe T; Fukumoto S; Okabe K; Inuzuka H
    Oncotarget; 2017 Feb; 8(6):9947-9960. PubMed ID: 28039480
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel intronic germline FLCN gene mutation in a patient with multiple ipsilateral renal neoplasms.
    Gatalica Z; Lilleberg SL; Vranic S; Eyzaguirre E; Orihuela E; Velagaleti G
    Hum Pathol; 2009 Dec; 40(12):1813-9. PubMed ID: 19733897
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.
    Hasumi H; Baba M; Hasumi Y; Lang M; Huang Y; Oh HF; Matsuo M; Merino MJ; Yao M; Ito Y; Furuya M; Iribe Y; Kodama T; Southon E; Tessarollo L; Nagashima K; Haines DC; Linehan WM; Schmidt LS
    Proc Natl Acad Sci U S A; 2015 Mar; 112(13):E1624-31. PubMed ID: 25775561
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma.
    Wilson C; Idziaszczyk S; Parry L; Guy C; Griffiths DF; Lazda E; Bayne RA; Smith AJ; Sampson JR; Cheadle JP
    Hum Mol Genet; 2005 Jul; 14(13):1839-50. PubMed ID: 15888477
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations of the Birt Hogg Dube gene in patients with multiple lung cysts and recurrent pneumothorax.
    Gunji Y; Akiyoshi T; Sato T; Kurihara M; Tominaga S; Takahashi K; Seyama K
    J Med Genet; 2007 Sep; 44(9):588-93. PubMed ID: 17496196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Birt-Hogg-Dubé (BHD) syndrome: report of two novel germline mutations in the folliculin (FLCN) gene.
    Palmirotta R; Donati P; Savonarola A; Cota C; Ferroni P; Guadagni F
    Eur J Dermatol; 2008; 18(4):382-6. PubMed ID: 18573707
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Spontaneous pneumothorax as the first manifestation of a hereditary condition with an increased renal cancer risk].
    Johannesma PC; Lammers JW; van Moorselaar RJ; Starink TM; Postmus PE; Menko FH
    Ned Tijdschr Geneeskd; 2009; 153():A581. PubMed ID: 19857281
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Birt-Hogg-Dubé syndrome: novel FLCN frameshift deletion in daughter and father with renal cell carcinomas.
    Näf E; Laubscher D; Hopfer H; Streit M; Matyas G
    Fam Cancer; 2016 Jan; 15(1):127-32. PubMed ID: 26342594
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic targeting the loss of the birt-hogg-dube suppressor gene.
    Lu X; Wei W; Fenton J; Nahorski MS; Rabai E; Reiman A; Seabra L; Nagy Z; Latif F; Maher ER
    Mol Cancer Ther; 2011 Jan; 10(1):80-9. PubMed ID: 21220493
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.