These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Platinated benzonaphthyridone is a stronger inhibitor of poly(ADP-ribose) polymerase-1 and a more potent anticancer agent than is the parent inhibitor. Wang B; Qian H; Yiu SM; Sun J; Zhu G Eur J Med Chem; 2014 Jan; 71():366-73. PubMed ID: 24361480 [TBL] [Abstract][Full Text] [Related]
6. Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors. Rhee HK; Lim SY; Jung MJ; Kwon Y; Kim MH; Choo HY Bioorg Med Chem; 2009 Nov; 17(21):7537-41. PubMed ID: 19800803 [TBL] [Abstract][Full Text] [Related]
7. Multi-targeted organometallic ruthenium(II)-arene anticancer complexes bearing inhibitors of poly(ADP-ribose) polymerase-1: A strategy to improve cytotoxicity. Wang Z; Qian H; Yiu SM; Sun J; Zhu G J Inorg Biochem; 2014 Feb; 131():47-55. PubMed ID: 24239912 [TBL] [Abstract][Full Text] [Related]
8. In silico identification of poly(ADP-ribose)polymerase-1 inhibitors and their chemosensitizing effects against cisplatin-resistant human gastric cancer cells. Le TV; Suh JH; Kim N; Park HJ Bioorg Med Chem Lett; 2013 May; 23(9):2642-6. PubMed ID: 23522835 [TBL] [Abstract][Full Text] [Related]
9. Synthesis, Cytotoxicity, and Mechanistic Investigation of Platinum(IV) Anticancer Complexes Conjugated with Poly(ADP-ribose) Polymerase Inhibitors. Xu Z; Li C; Zhou Q; Deng Z; Tong Z; Tse MK; Zhu G Inorg Chem; 2019 Dec; 58(23):16279-16291. PubMed ID: 31738050 [TBL] [Abstract][Full Text] [Related]
10. Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations. Geraets L; Moonen HJ; Wouters EF; Bast A; Hageman GJ Biochem Pharmacol; 2006 Sep; 72(7):902-10. PubMed ID: 16870158 [TBL] [Abstract][Full Text] [Related]
11. PARP1 impact on DNA repair of platinum adducts: preclinical and clinical read-outs. Olaussen KA; Adam J; Vanhecke E; Vielh P; Pirker R; Friboulet L; Popper H; Robin A; Commo F; Thomale J; Kayitalire L; Filipits M; Le Chevalier T; André F; Brambilla E; Soria JC Lung Cancer; 2013 May; 80(2):216-22. PubMed ID: 23410825 [TBL] [Abstract][Full Text] [Related]
12. Chemopotentiation of temozolomide, irinotecan, and cisplatin activity by CEP-6800, a poly(ADP-ribose) polymerase inhibitor. Miknyoczki SJ; Jones-Bolin S; Pritchard S; Hunter K; Zhao H; Wan W; Ator M; Bihovsky R; Hudkins R; Chatterjee S; Klein-Szanto A; Dionne C; Ruggeri B Mol Cancer Ther; 2003 Apr; 2(4):371-82. PubMed ID: 12700281 [TBL] [Abstract][Full Text] [Related]
13. Identification of nuclear proteins that interact with platinum-modified DNA by photoaffinity labeling. Zhang CX; Chang PV; Lippard SJ J Am Chem Soc; 2004 Jun; 126(21):6536-7. PubMed ID: 15161265 [TBL] [Abstract][Full Text] [Related]
14. Discovery of 1-substituted benzyl-quinazoline-2,4(1H,3H)-dione derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors. Yao H; Ji M; Zhu Z; Zhou J; Cao R; Chen X; Xu B Bioorg Med Chem; 2015 Feb; 23(4):681-93. PubMed ID: 25614115 [TBL] [Abstract][Full Text] [Related]
15. Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells. Kuang J; Wang YL; Xiao M; Tang Y; Chen WW; Song GL; Yang X; Li M Oncol Rep; 2014 May; 31(5):2335-43. PubMed ID: 24676941 [TBL] [Abstract][Full Text] [Related]
16. Delocalization of nucleolar poly(ADP-ribose) polymerase-1 to the nucleoplasm and its novel link to cellular sensitivity to DNA damage. Rancourt A; Satoh MS DNA Repair (Amst); 2009 Mar; 8(3):286-97. PubMed ID: 19144573 [TBL] [Abstract][Full Text] [Related]
17. Role of poly(ADP-ribose)polymerase in cisplatin-induced injury in LLC-PK1 cells. Shino Y; Itoh Y; Kubota T; Yano T; Sendo T; Oishi R Free Radic Biol Med; 2003 Oct; 35(8):966-77. PubMed ID: 14556861 [TBL] [Abstract][Full Text] [Related]
18. Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy. Heitz F; Harter P; Ewald-Riegler N; Papsdorf M; Kommoss S; du Bois A Expert Rev Anticancer Ther; 2010 Jul; 10(7):1125-36. PubMed ID: 20645701 [TBL] [Abstract][Full Text] [Related]
19. Poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide enhances apoptosis induction by platinum complexes in cisplatin-resistant tumor cells. Nguewa PA; Fuertes MA; Cepeda V; Alonso C; Quevedo C; Soto M; Pérez JM Med Chem; 2006 Jan; 2(1):47-53. PubMed ID: 16787355 [TBL] [Abstract][Full Text] [Related]
20. Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA. Mendes F; Groessl M; Nazarov AA; Tsybin YO; Sava G; Santos I; Dyson PJ; Casini A J Med Chem; 2011 Apr; 54(7):2196-206. PubMed ID: 21370912 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]