262 related articles for article (PubMed ID: 18981180)
1. Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.
Passero CJ; Mueller GM; Rondon-Berrios H; Tofovic SP; Hughey RP; Kleyman TR
J Biol Chem; 2008 Dec; 283(52):36586-91. PubMed ID: 18981180
[TBL] [Abstract][Full Text] [Related]
2. TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage site.
Passero CJ; Mueller GM; Myerburg MM; Carattino MD; Hughey RP; Kleyman TR
Am J Physiol Renal Physiol; 2012 Jan; 302(1):F1-8. PubMed ID: 21993886
[TBL] [Abstract][Full Text] [Related]
3. Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease.
Carattino MD; Mueller GM; Palmer LG; Frindt G; Rued AC; Hughey RP; Kleyman TR
Am J Physiol Renal Physiol; 2014 Nov; 307(9):F1080-7. PubMed ID: 25209858
[TBL] [Abstract][Full Text] [Related]
4. Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel.
Haerteis S; Krappitz M; Diakov A; Krappitz A; Rauh R; Korbmacher C
J Gen Physiol; 2012 Oct; 140(4):375-89. PubMed ID: 22966015
[TBL] [Abstract][Full Text] [Related]
5. Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.
Bruns JB; Carattino MD; Sheng S; Maarouf AB; Weisz OA; Pilewski JM; Hughey RP; Kleyman TR
J Biol Chem; 2007 Mar; 282(9):6153-60. PubMed ID: 17199078
[TBL] [Abstract][Full Text] [Related]
6. Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation.
Carattino MD; Hughey RP; Kleyman TR
J Biol Chem; 2008 Sep; 283(37):25290-25295. PubMed ID: 18650438
[TBL] [Abstract][Full Text] [Related]
7. Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels.
Diakov A; Bera K; Mokrushina M; Krueger B; Korbmacher C
J Physiol; 2008 Oct; 586(19):4587-608. PubMed ID: 18669538
[TBL] [Abstract][Full Text] [Related]
8. The epithelial Na
Zachar R; Mikkelsen MK; Skjødt K; Marcussen N; Zamani R; Jensen BL; Svenningsen P
Pflugers Arch; 2019 Dec; 471(11-12):1383-1396. PubMed ID: 31654198
[TBL] [Abstract][Full Text] [Related]
9. Preferential assembly of epithelial sodium channel (ENaC) subunits in Xenopus oocytes: role of furin-mediated endogenous proteolysis.
Harris M; Garcia-Caballero A; Stutts MJ; Firsov D; Rossier BC
J Biol Chem; 2008 Mar; 283(12):7455-63. PubMed ID: 18195015
[TBL] [Abstract][Full Text] [Related]
10. Plasmin in nephrotic urine activates the epithelial sodium channel.
Svenningsen P; Bistrup C; Friis UG; Bertog M; Haerteis S; Krueger B; Stubbe J; Jensen ON; Thiesson HC; Uhrenholt TR; Jespersen B; Jensen BL; Korbmacher C; Skøtt O
J Am Soc Nephrol; 2009 Feb; 20(2):299-310. PubMed ID: 19073825
[TBL] [Abstract][Full Text] [Related]
11. ENaC proteolytic regulation by channel-activating protease 2.
García-Caballero A; Dang Y; He H; Stutts MJ
J Gen Physiol; 2008 Nov; 132(5):521-35. PubMed ID: 18852303
[TBL] [Abstract][Full Text] [Related]
12. Plasmin improves blood-gas barrier function in oedematous lungs by cleaving epithelial sodium channels.
Zhao R; Ali G; Nie HG; Chang Y; Bhattarai D; Su X; Zhao X; Matthay MA; Ji HL
Br J Pharmacol; 2020 Jul; 177(13):3091-3106. PubMed ID: 32133621
[TBL] [Abstract][Full Text] [Related]
13. Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.
Sheng S; Carattino MD; Bruns JB; Hughey RP; Kleyman TR
Am J Physiol Renal Physiol; 2006 Jun; 290(6):F1488-96. PubMed ID: 16449353
[TBL] [Abstract][Full Text] [Related]
14. Influence of proteolytic cleavage of ENaC's γ subunit upon Na
Ray EC; Nickerson A; Sheng S; Carrisoza-Gaytan R; Lam T; Marciszyn A; Zhang L; Jordahl A; Bi C; Winfrey A; Kou Z; Gingras S; Kirabo A; Satlin LM; Kleyman TR
Am J Physiol Renal Physiol; 2024 Jun; 326(6):F1066-F1077. PubMed ID: 38634134
[TBL] [Abstract][Full Text] [Related]
15. Proteolytic activation of the human epithelial sodium channel by trypsin IV and trypsin I involves distinct cleavage sites.
Haerteis S; Krappitz A; Krappitz M; Murphy JE; Bertog M; Krueger B; Nacken R; Chung H; Hollenberg MD; Knecht W; Bunnett NW; Korbmacher C
J Biol Chem; 2014 Jul; 289(27):19067-78. PubMed ID: 24841206
[TBL] [Abstract][Full Text] [Related]
16. Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations.
Svenningsen P; Uhrenholt TR; Palarasah Y; Skjødt K; Jensen BL; Skøtt O
Am J Physiol Regul Integr Comp Physiol; 2009 Dec; 297(6):R1733-41. PubMed ID: 19793956
[TBL] [Abstract][Full Text] [Related]
17. Urine exosomes from healthy and hypertensive pregnancies display elevated level of α-subunit and cleaved α- and γ-subunits of the epithelial sodium channel-ENaC.
Nielsen MR; Frederiksen-Møller B; Zachar R; Jørgensen JS; Hansen MR; Ydegaard R; Svenningsen P; Buhl K; Jensen BL
Pflugers Arch; 2017 Sep; 469(9):1107-1119. PubMed ID: 28405801
[TBL] [Abstract][Full Text] [Related]
18. Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel.
Passero CJ; Carattino MD; Kashlan OB; Myerburg MM; Hughey RP; Kleyman TR
Am J Physiol Renal Physiol; 2010 Oct; 299(4):F854-61. PubMed ID: 20630937
[TBL] [Abstract][Full Text] [Related]
19. Incorporation of the δ-subunit into the epithelial sodium channel (ENaC) generates protease-resistant ENaCs in
Wichmann L; Vowinkel KS; Perniss A; Manzini I; Althaus M
J Biol Chem; 2018 May; 293(18):6647-6658. PubMed ID: 29576549
[TBL] [Abstract][Full Text] [Related]
20. Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells.
Andersen H; Friis UG; Hansen PB; Svenningsen P; Henriksen JE; Jensen BL
Nephrol Dial Transplant; 2015 May; 30(5):781-9. PubMed ID: 25609736
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]