210 related articles for article (PubMed ID: 18989148)
1. Severe hepatotoxicity with high 6-methylmercaptopurine nucleotide concentrations after thiopurine dose escalation due to low 6-thioguanine nucleotides.
Gardiner SJ; Gearry RB; Burt MJ; Ding SL; Barclay ML
Eur J Gastroenterol Hepatol; 2008 Dec; 20(12):1238-42. PubMed ID: 18989148
[TBL] [Abstract][Full Text] [Related]
2. Metabolite monitoring to guide thiopurine therapy in systemic autoimmune diseases.
Chapdelaine A; Mansour AM; Troyanov Y; Williamson DR; Doré M
Clin Rheumatol; 2017 Jun; 36(6):1341-1348. PubMed ID: 28130685
[TBL] [Abstract][Full Text] [Related]
3. Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease.
Jharap B; de Boer NK; Stokkers P; Hommes DW; Oldenburg B; Dijkstra G; van der Woude CJ; de Jong DJ; Mulder CJ; van Elburg RM; van Bodegraven AA;
Gut; 2014 Mar; 63(3):451-7. PubMed ID: 23424097
[TBL] [Abstract][Full Text] [Related]
4. Thiopurine metabolite ratios for monitoring therapy in pediatric Crohn disease.
Kopylov U; Amre D; Theoret Y; Deslandres C; Seidman EG
J Pediatr Gastroenterol Nutr; 2014 Oct; 59(4):511-5. PubMed ID: 24918978
[TBL] [Abstract][Full Text] [Related]
5. Febuxostat as a novel option to optimize thiopurines' metabolism in patients with inadequate metabolite levels.
Doré M; Frenette AJ; Mansour AM; Troyanov Y; Bégin J
Ann Pharmacother; 2014 May; 48(5):648-51. PubMed ID: 24523395
[TBL] [Abstract][Full Text] [Related]
6. Therapeutic drug monitoring of thiopurine metabolites in adult thiopurine tolerant IBD patients on maintenance therapy.
Gilissen LP; Wong DR; Engels LG; Bierau J; Bakker JA; Paulussen AD; Romberg-Camps MJ; Stronkhorst A; Bus P; Bos LP; Hooymans PM; Stockbrügger RW; Neef C; Masclee AA
J Crohns Colitis; 2012 Jul; 6(6):698-707. PubMed ID: 22398098
[TBL] [Abstract][Full Text] [Related]
7. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice.
Gearry RB; Barclay ML; Roberts RL; Harraway J; Zhang M; Pike LS; George PM; Florkowski CM
Intern Med J; 2005 Oct; 35(10):580-5. PubMed ID: 16207256
[TBL] [Abstract][Full Text] [Related]
8. Use of allopurinol in children with acute lymphoblastic leukemia to reduce skewed thiopurine metabolism.
Brackett J; Schafer ES; Leung DH; Bernhardt MB
Pediatr Blood Cancer; 2014 Jun; 61(6):1114-7. PubMed ID: 24376133
[TBL] [Abstract][Full Text] [Related]
9. Measurement of red blood cell 6-thioguanine nucleotide is beneficial in azathioprine maintenance therapy of Chinese Crohn's disease patients.
Liu Q; Wang Y; Mei Q; Han W; Hu J; Hu N
Scand J Gastroenterol; 2016 Sep; 51(9):1093-9. PubMed ID: 27152547
[TBL] [Abstract][Full Text] [Related]
10. The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients.
Wong DR; Pierik M; Seinen ML; van Bodegraven AA; Gilissen LP; Bus P; Bakker JA; Masclee AA; Neef C; Engels LG; Hooymans PM
J Crohns Colitis; 2014 Feb; 8(2):120-8. PubMed ID: 23932783
[TBL] [Abstract][Full Text] [Related]
11. High TPMT enzyme activity does not explain drug resistance due to preferential 6-methylmercaptopurine production in patients on thiopurine treatment.
van Egmond R; Chin P; Zhang M; Sies CW; Barclay ML
Aliment Pharmacol Ther; 2012 May; 35(10):1181-9. PubMed ID: 22486532
[TBL] [Abstract][Full Text] [Related]
12. Monitoring of long-term thiopurine therapy among adults with inflammatory bowel disease.
Hindorf U; Lyrenäs E; Nilsson A; Schmiegelow K
Scand J Gastroenterol; 2004 Nov; 39(11):1105-12. PubMed ID: 15545169
[TBL] [Abstract][Full Text] [Related]
13. Mucosal improvement in patients with moderate to severe postoperative endoscopic recurrence of Crohn's disease and azathioprine metabolite levels.
Angelberger S; Schaeffeler E; Teml A; Petritsch W; Shonova O; Lukas M; Bar-Meir S; Dilger K; Greinwald R; Mueller R; Stange EF; Herrlinger KR; Schwab M; Reinisch W
Inflamm Bowel Dis; 2013 Mar; 19(3):590-8. PubMed ID: 23388543
[TBL] [Abstract][Full Text] [Related]
14. Early Assessment of Thiopurine Metabolites Identifies Patients at Risk of Thiopurine-induced Leukopenia in Inflammatory Bowel Disease.
Wong DR; Coenen MJ; Vermeulen SH; Derijks LJ; van Marrewijk CJ; Klungel OH; Scheffer H; Franke B; Guchelaar HJ; de Jong DJ; Engels LG; Verbeek AL; Hooymans PM;
J Crohns Colitis; 2017 Feb; 11(2):175-184. PubMed ID: 27402913
[TBL] [Abstract][Full Text] [Related]
15. Improved method for therapeutic drug monitoring of 6-thioguanine nucleotides and 6-methylmercaptopurine in whole-blood by LC/MSMS using isotope-labeled internal standards.
Kirchherr H; Shipkova M; von Ahsen N
Ther Drug Monit; 2013 Jun; 35(3):313-21. PubMed ID: 23666567
[TBL] [Abstract][Full Text] [Related]
16. Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy.
Dervieux T; Meyer G; Barham R; Matsutani M; Barry M; Boulieu R; Neri B; Seidman E
Clin Chem; 2005 Nov; 51(11):2074-84. PubMed ID: 16166171
[TBL] [Abstract][Full Text] [Related]
17. Novel assay to improve therapeutic drug monitoring of thiopurines in inflammatory bowel disease.
Vikingsson S; Andersson D; Almer S; Peterson C; Hindorf U
J Crohns Colitis; 2014 Dec; 8(12):1702-9. PubMed ID: 25239576
[TBL] [Abstract][Full Text] [Related]
18. Routinely Established Skewed Thiopurine Metabolism Leads to a Strikingly High Rate of Early Therapeutic Failure in Patients With Inflammatory Bowel Disease.
Kreijne JE; Seinen ML; Wilhelm AJ; Bouma G; Mulder CJ; van Bodegraven AA; de Boer NK
Ther Drug Monit; 2015 Dec; 37(6):797-804. PubMed ID: 25853923
[TBL] [Abstract][Full Text] [Related]
19. Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother-infant pairs.
Gardiner SJ; Gearry RB; Roberts RL; Zhang M; Barclay ML; Begg EJ
Br J Clin Pharmacol; 2006 Oct; 62(4):453-6. PubMed ID: 16995866
[TBL] [Abstract][Full Text] [Related]
20. Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio.
Gardiner SJ; Gearry RB; Burt MJ; Chalmers-Watson T; Chapman BA; Ross AG; Stedman CA; Huelsen A; Barclay ML
J Gastroenterol Hepatol; 2011 Jan; 26(1):49-54. PubMed ID: 21175793
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]