BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 18989978)

  • 1. Molecular-targeted antitumor agents. 19. Furospongolide from a marine Lendenfeldia sp. sponge inhibits hypoxia-inducible factor-1 activation in breast tumor cells.
    Liu Y; Liu R; Mao SC; Morgan JB; Jekabsons MB; Zhou YD; Nagle DG
    J Nat Prod; 2008 Nov; 71(11):1854-60. PubMed ID: 18989978
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia-selective antitumor agents: norsesterterpene peroxides from the marine sponge Diacarnus levii preferentially suppress the growth of tumor cells under hypoxic conditions.
    Dai J; Liu Y; Zhou YD; Nagle DG
    J Nat Prod; 2007 Jan; 70(1):130-3. PubMed ID: 17253866
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular-targeted antitumor agents. 15. Neolamellarins from the marine sponge Dendrilla nigra inhibit hypoxia-inducible factor-1 activation and secreted vascular endothelial growth factor production in breast tumor cells.
    Liu R; Liu Y; Zhou YD; Nagle DG
    J Nat Prod; 2007 Nov; 70(11):1741-5. PubMed ID: 17958397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sodwanone and yardenone triterpenes from a South African species of the marine sponge Axinella inhibit hypoxia-inducible factor-1 (HIF-1) activation in both breast and prostate tumor cells.
    Dai J; Fishback JA; Zhou YD; Nagle DG
    J Nat Prod; 2006 Dec; 69(12):1715-20. PubMed ID: 17190448
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways.
    Liu Y; Veena CK; Morgan JB; Mohammed KA; Jekabsons MB; Nagle DG; Zhou YD
    J Biol Chem; 2009 Feb; 284(9):5859-68. PubMed ID: 19091749
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytotoxic metabolites from an Indonesian sponge Lendenfeldia sp.
    Dai J; Liu Y; Zhou YD; Nagle DG
    J Nat Prod; 2007 Nov; 70(11):1824-6. PubMed ID: 17958396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1.
    Hodges TW; Hossain CF; Kim YP; Zhou YD; Nagle DG
    J Nat Prod; 2004 May; 67(5):767-71. PubMed ID: 15165135
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Laurenditerpenol, a new diterpene from the tropical marine alga Laurenciaintricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells.
    Mohammed KA; Hossain CF; Zhang L; Bruick RK; Zhou YD; Nagle DG
    J Nat Prod; 2004 Dec; 67(12):2002-7. PubMed ID: 15620241
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction.
    Goey AK; Chau CH; Sissung TM; Cook KM; Venzon DJ; Castro A; Ransom TR; Henrich CJ; McKee TC; McMahon JB; Grkovic T; Cadelis MM; Copp BR; Gustafson KR; Figg WD
    J Nat Prod; 2016 May; 79(5):1267-75. PubMed ID: 27140429
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structures and potential antitumor activity of sesterterpenes from the marine sponge Hyrtios communis.
    Li J; Du L; Kelly M; Zhou YD; Nagle DG
    J Nat Prod; 2013 Aug; 76(8):1492-7. PubMed ID: 23944963
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lipophilic 2,5-disubstituted pyrroles from the marine sponge Mycale sp. inhibit mitochondrial respiration and HIF-1 activation.
    Mao SC; Liu Y; Morgan JB; Jekabsons MB; Zhou YD; Nagle DG
    J Nat Prod; 2009 Nov; 72(11):1927-36. PubMed ID: 19845338
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells.
    Du L; Mahdi F; Datta S; Jekabsons MB; Zhou YD; Nagle DG
    J Nat Prod; 2012 Sep; 75(9):1553-9. PubMed ID: 22938093
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytotoxic furanosesterterpenes from a marine sponge Psammocinia sp.
    Choi K; Hong J; Lee CO; Kim DK; Sim CJ; Im KS; Jung JH
    J Nat Prod; 2004 Jul; 67(7):1186-9. PubMed ID: 15270579
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New cytotoxic metabolites from a marine sponge Homaxinella sp.
    Mansoor TA; Hong J; Lee CO; Sim CJ; Im KS; Lee DS; Jung JH
    J Nat Prod; 2004 Apr; 67(4):721-4. PubMed ID: 15104515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hyrtioseragamines A and B, new alkaloids from the sponge Hyrtios species.
    Takahashi Y; Iinuma Y; Kubota T; Tsuda M; Sekiguchi M; Mikami Y; Fromont J; Kobayashi J
    Org Lett; 2011 Feb; 13(4):628-31. PubMed ID: 21247076
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzochromenones from the marine crinoid Comantheria rotula inhibit hypoxia-inducible factor-1 (HIF-1) in cell-based reporter assays and differentially suppress the growth of certain tumor cell lines.
    Dai J; Liu Y; Jia H; Zhou YD; Nagle DG
    J Nat Prod; 2007 Sep; 70(9):1462-6. PubMed ID: 17844994
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Marine spongian sesquiterpene phenols, dictyoceratin-C and smenospondiol, display hypoxia-selective growth inhibition against cancer cells.
    Arai M; Kawachi T; Sato H; Setiawan A; Kobayashi M
    Bioorg Med Chem Lett; 2014 Jul; 24(14):3155-7. PubMed ID: 24865416
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
    Rapisarda A; Uranchimeg B; Scudiero DA; Selby M; Sausville EA; Shoemaker RH; Melillo G
    Cancer Res; 2002 Aug; 62(15):4316-24. PubMed ID: 12154035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bioactive sulfated sesterterpene alkaloids and sesterterpene sulfates from the marine sponge Fasciospongia sp.
    Yao G; Kondratyuk TP; Tan GT; Pezzuto JM; Chang LC
    J Nat Prod; 2009 Feb; 72(2):319-23. PubMed ID: 19178162
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC; Lee CF; Huang WH; Chou TC
    Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.