BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

383 related articles for article (PubMed ID: 18991392)

  • 1. Function of Glu-469' in the acid-base catalysis of thioredoxin reductase from Drosophila melanogaster.
    Huang HH; Arscott LD; Ballou DP; Williams CH
    Biochemistry; 2008 Dec; 47(48):12769-76. PubMed ID: 18991392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acid-base catalysis in the mechanism of thioredoxin reductase from Drosophila melanogaster.
    Huang HH; Arscott LD; Ballou DP; Williams CH
    Biochemistry; 2008 Feb; 47(6):1721-31. PubMed ID: 18211101
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The relationship of the redox potentials of thioredoxin and thioredoxin reductase from Drosophila melanogaster to the enzymatic mechanism: reduced thioredoxin is the reductant of glutathione in Drosophila.
    Cheng Z; Arscott LD; Ballou DP; Williams CH
    Biochemistry; 2007 Jul; 46(26):7875-85. PubMed ID: 17550271
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Studies of an active site mutant of the selenoprotein thioredoxin reductase: the Ser-Cys-Cys-Ser motif of the insect orthologue is not sufficient to replace the Cys-Sec dyad in the mammalian enzyme.
    Johansson L; Arscott LD; Ballou DP; Williams CH; Arnér ES
    Free Radic Biol Med; 2006 Aug; 41(4):649-56. PubMed ID: 16863998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thioredoxin reductase from Plasmodium falciparum: evidence for interaction between the C-terminal cysteine residues and the active site disulfide-dithiol.
    Wang PF; Arscott LD; Gilberger TW; Müller S; Williams CH
    Biochemistry; 1999 Mar; 38(10):3187-96. PubMed ID: 10074374
    [TBL] [Abstract][Full Text] [Related]  

  • 6. General acid/base catalysis in the active site of Escherichia coli thioredoxin.
    Chivers PT; Raines RT
    Biochemistry; 1997 Dec; 36(50):15810-6. PubMed ID: 9398311
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity.
    Davioud-Charvet E; McLeish MJ; Veine DM; Giegel D; Arscott LD; Andricopulo AD; Becker K; Müller S; Schirmer RH; Williams CH; Kenyon GL
    Biochemistry; 2003 Nov; 42(45):13319-30. PubMed ID: 14609342
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The mechanism of high Mr thioredoxin reductase from Drosophila melanogaster.
    Bauer H; Massey V; Arscott LD; Schirmer RH; Ballou DP; Williams CH
    J Biol Chem; 2003 Aug; 278(35):33020-8. PubMed ID: 12816954
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
    Waksman G; Krishna TS; Williams CH; Kuriyan J
    J Mol Biol; 1994 Feb; 236(3):800-16. PubMed ID: 8114095
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster.
    Kanzok SM; Fechner A; Bauer H; Ulschmid JK; Müller HM; Botella-Munoz J; Schneuwly S; Schirmer R; Becker K
    Science; 2001 Jan; 291(5504):643-6. PubMed ID: 11158675
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of buried charged groups on cysteine thiol ionization and reactivity in Escherichia coli thioredoxin: structural and functional characterization of mutants of Asp 26 and Lys 57.
    Dyson HJ; Jeng MF; Tennant LL; Slaby I; Lindell M; Cui DS; Kuprin S; Holmgren A
    Biochemistry; 1997 Mar; 36(9):2622-36. PubMed ID: 9054569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity.
    Lee SR; Bar-Noy S; Kwon J; Levine RL; Stadtman TC; Rhee SG
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2521-6. PubMed ID: 10688911
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thioredoxin reductase-thioredoxin fusion enzyme from Mycobacterium leprae: comparison with the separately expressed thioredoxin reductase.
    Wang PF; Marcinkeviciene J; Williams CH; Blanchard JS
    Biochemistry; 1998 Nov; 37(46):16378-89. PubMed ID: 9819230
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The conserved histidine 106 of large thioredoxin reductases is likely to have a structural role but not a base catalyst function.
    Jacob J; Schirmer RH; Gromer S
    FEBS Lett; 2005 Jan; 579(3):745-8. PubMed ID: 15670839
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enzyme-monitored turnover of Escherichia coli thioredoxin reductase: insights for catalysis.
    Lennon BW; Williams CH
    Biochemistry; 1996 Apr; 35(15):4704-12. PubMed ID: 8664260
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant.
    Zhao R; Masayasu H; Holmgren A
    Proc Natl Acad Sci U S A; 2002 Jun; 99(13):8579-84. PubMed ID: 12070343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of acid-base catalytic residues of high-Mr thioredoxin reductase from Plasmodium falciparum.
    McMillan PJ; Arscott LD; Ballou DP; Becker K; Williams CH; Müller S
    J Biol Chem; 2006 Nov; 281(44):32967-77. PubMed ID: 16950793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and conformer analysis of a novel redox-active motif, Pro-Ala-Ser-Cys-Cys-Ser, in Drosophila thioredoxin reductase by semiempirical molecular orbital calculation.
    Kuwahara M; Tamura T; Kawamura K; Inagaki K
    Biosci Biotechnol Biochem; 2011; 75(3):516-21. PubMed ID: 21389620
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis.
    Fritz-Wolf K; Urig S; Becker K
    J Mol Biol; 2007 Jun; 370(1):116-27. PubMed ID: 17512005
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A mechanistic investigation of the C-terminal redox motif of thioredoxin reductase from Plasmodium falciparum.
    Snider GW; Dustin CM; Ruggles EL; Hondal RJ
    Biochemistry; 2014 Jan; 53(3):601-9. PubMed ID: 24400600
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.