BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 18991865)

  • 1. Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration.
    Carvour M; Song C; Kaul S; Anantharam V; Kanthasamy A; Kanthasamy A
    Ann N Y Acad Sci; 2008 Oct; 1139():197-205. PubMed ID: 18991865
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.
    Anantharam V; Kitazawa M; Latchoumycandane C; Kanthasamy A; Kanthasamy AG
    Ann N Y Acad Sci; 2004 Dec; 1035():271-89. PubMed ID: 15681813
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.
    Afeseh Ngwa H; Kanthasamy A; Anantharam V; Song C; Witte T; Houk R; Kanthasamy AG
    Toxicol Appl Pharmacol; 2009 Oct; 240(2):273-85. PubMed ID: 19646462
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.
    Kitazawa M; Anantharam V; Kanthasamy AG
    Neuroscience; 2003; 119(4):945-64. PubMed ID: 12831855
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models.
    Kanthasamy AG; Anantharam V; Zhang D; Latchoumycandane C; Jin H; Kaul S; Kanthasamy A
    Free Radic Biol Med; 2006 Nov; 41(10):1578-89. PubMed ID: 17045926
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
    Kaul S; Kanthasamy A; Kitazawa M; Anantharam V; Kanthasamy AG
    Eur J Neurosci; 2003 Sep; 18(6):1387-401. PubMed ID: 14511319
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease.
    Latchoumycandane C; Anantharam V; Jin H; Kanthasamy A; Kanthasamy A
    Toxicol Appl Pharmacol; 2011 Nov; 256(3):314-23. PubMed ID: 21846476
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.
    Kanthasamy AG; Kitazawa M; Yang Y; Anantharam V; Kanthasamy A
    Mol Brain; 2008 Oct; 1():12. PubMed ID: 18945348
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
    Kaul S; Anantharam V; Yang Y; Choi CJ; Kanthasamy A; Kanthasamy AG
    J Biol Chem; 2005 Aug; 280(31):28721-30. PubMed ID: 15961393
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease.
    Anantharam V; Lehrmann E; Kanthasamy A; Yang Y; Banerjee P; Becker KG; Freed WJ; Kanthasamy AG
    Neurochem Int; 2007 May; 50(6):834-47. PubMed ID: 17397968
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
    Anantharam V; Kitazawa M; Wagner J; Kaul S; Kanthasamy AG
    J Neurosci; 2002 Mar; 22(5):1738-51. PubMed ID: 11880503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.
    Latchoumycandane C; Anantharam V; Kitazawa M; Yang Y; Kanthasamy A; Kanthasamy AG
    J Pharmacol Exp Ther; 2005 Apr; 313(1):46-55. PubMed ID: 15608081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.
    Kaul S; Anantharam V; Kanthasamy A; Kanthasamy AG
    Brain Res Mol Brain Res; 2005 Sep; 139(1):137-52. PubMed ID: 15978696
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation.
    Sun F; Kanthasamy A; Song C; Yang Y; Anantharam V; Kanthasamy AG
    J Cell Mol Med; 2008 Dec; 12(6A):2467-81. PubMed ID: 18298651
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model.
    Saminathan H; Asaithambi A; Anantharam V; Kanthasamy AG; Kanthasamy A
    Neurotoxicology; 2011 Oct; 32(5):567-77. PubMed ID: 21801747
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing roles of prion protein in oxidative stress- and ER stress-induced apoptotic signaling.
    Anantharam V; Kanthasamy A; Choi CJ; Martin DP; Latchoumycandane C; Richt JA; Kanthasamy AG
    Free Radic Biol Med; 2008 Dec; 45(11):1530-41. PubMed ID: 18835352
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heterozygous huntingtin promotes cadmium neurotoxicity and neurodegeneration in striatal cells via altered metal transport and protein kinase C delta dependent oxidative stress and apoptosis signaling mechanisms.
    Kwakye GF; Jiménez JA; Thomas MG; Kingsley BA; McIIvin M; Saito MA; Korley EM
    Neurotoxicology; 2019 Jan; 70():48-61. PubMed ID: 30399392
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration.
    Yang Y; Kaul S; Zhang D; Anantharam V; Kanthasamy AG
    Mol Cell Neurosci; 2004 Mar; 25(3):406-21. PubMed ID: 15033169
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A comparative study of proteasomal inhibition and apoptosis induced in N27 mesencephalic cells by dopamine and MG132.
    Zafar KS; Inayat-Hussain SH; Ross D
    J Neurochem; 2007 Aug; 102(3):913-21. PubMed ID: 17504267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oxidative neurotoxicity in rat cerebral cortex neurons: synergistic effects of H2O2 and NO on apoptosis involving activation of p38 mitogen-activated protein kinase and caspase-3.
    Wang JY; Shum AY; Ho YJ; Wang JY
    J Neurosci Res; 2003 May; 72(4):508-19. PubMed ID: 12704812
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.