BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 18996448)

  • 1. alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ.
    Zündorf G; Kahlert S; Bunik VI; Reiser G
    Neuroscience; 2009 Jan; 158(2):610-6. PubMed ID: 18996448
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glutamate-mediated influx of extracellular Ca2+ is coupled with reactive oxygen species generation in cultured hippocampal neurons but not in astrocytes.
    Kahlert S; Zündorf G; Reiser G
    J Neurosci Res; 2005 Jan 1-15; 79(1-2):262-71. PubMed ID: 15578732
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid.
    Ambrus A; Tretter L; Adam-Vizi V
    J Neurochem; 2009 May; 109 Suppl 1():222-9. PubMed ID: 19393031
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simultaneous age-related depolarization of mitochondrial membrane potential and increased mitochondrial reactive oxygen species production correlate with age-related glutamate excitotoxicity in rat hippocampal neurons.
    Parihar MS; Brewer GJ
    J Neurosci Res; 2007 Apr; 85(5):1018-32. PubMed ID: 17335078
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death.
    Huang HM; Ou HC; Xu H; Chen HL; Fowler C; Gibson GE
    J Neurosci Res; 2003 Oct; 74(2):309-17. PubMed ID: 14515360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphono analogues of 2-oxoglutarate protect cerebellar granule neurons upon glutamate excitotoxicity.
    Bunik VI; Kabysheva MS; Klimuk EI; Storozhevykh TP; Pinelis VG
    Ann N Y Acad Sci; 2009 Aug; 1171():521-9. PubMed ID: 19723099
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Secretory PLA2-IIA and ROS generation in peripheral mitochondria are critical for neuronal death.
    Mathisen GH; Thorkildsen IH; Paulsen RE
    Brain Res; 2007 Jun; 1153():43-51. PubMed ID: 17462609
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells.
    Bunik VI; Denton TT; Xu H; Thompson CM; Cooper AJ; Gibson GE
    Biochemistry; 2005 Aug; 44(31):10552-61. PubMed ID: 16060664
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons.
    Santos SS; Gibson GE; Cooper AJ; Denton TT; Thompson CM; Bunik VI; Alves PM; Sonnewald U
    J Neurosci Res; 2006 Feb; 83(3):450-8. PubMed ID: 16416424
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Consequences of the α-ketoglutarate dehydrogenase inhibition for neuronal metabolism and survival: implications for neurodegenerative diseases.
    Trofimova LK; Araújo WL; Strokina AA; Fernie AR; Bettendorff L; Bunik VI
    Curr Med Chem; 2012; 19(34):5895-906. PubMed ID: 23061627
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Calcium-dependent production of reactive oxygen species is involved in neuronal damage induced during glycolysis inhibition in cultured hippocampal neurons.
    Hernández-Fonseca K; Cárdenas-Rodríguez N; Pedraza-Chaverri J; Massieu L
    J Neurosci Res; 2008 Jun; 86(8):1768-80. PubMed ID: 18293416
    [TBL] [Abstract][Full Text] [Related]  

  • 12. P2Y receptor-activating nucleotides modulate cellular reactive oxygen species production in dissociated hippocampal astrocytes and neurons in culture independent of parallel cytosolic Ca(2+) rise and change in mitochondrial potential.
    Kahlert S; Blaser T; Tulapurkar M; Reiser G
    J Neurosci Res; 2007 Nov; 85(15):3443-56. PubMed ID: 17492786
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thrombin-induced oxidative stress contributes to the death of hippocampal neurons: role of neuronal NADPH oxidase.
    Park KW; Jin BK
    J Neurosci Res; 2008 Apr; 86(5):1053-63. PubMed ID: 18183616
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacological investigation of mitochondrial ca(2+) transport in central neurons: studies with CGP-37157, an inhibitor of the mitochondrial Na(+)-Ca(2+) exchanger.
    Scanlon JM; Brocard JB; Stout AK; Reynolds IJ
    Cell Calcium; 2000; 28(5-6):317-27. PubMed ID: 11115371
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gap-junction blocker carbenoxolone differentially enhances NMDA-induced cell death in hippocampal neurons and astrocytes in co-culture.
    Zündorf G; Kahlert S; Reiser G
    J Neurochem; 2007 Jul; 102(2):508-21. PubMed ID: 17403140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?
    Chen H; Denton TT; Xu H; Calingasan N; Beal MF; Gibson GE
    J Neurochem; 2016 Dec; 139(5):823-838. PubMed ID: 27580471
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative alpha-ketoglutarate dehydrogenase activity staining in brain sections and in cultured cells.
    Park LC; Calingasan NY; Sheu KF; Gibson GE
    Anal Biochem; 2000 Jan; 277(1):86-93. PubMed ID: 10610692
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Implications of enzyme deficiencies on mitochondrial energy metabolism and reactive oxygen species formation of neurons involved in rotenone-induced Parkinson's disease: a model-based analysis.
    Berndt N; Holzhütter HG; Bulik S
    FEBS J; 2013 Oct; 280(20):5080-93. PubMed ID: 23937586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Superoxide (*O2- ) production in CA1 neurons of rat hippocampal slices exposed to graded levels of oxygen.
    D'Agostino DP; Putnam RW; Dean JB
    J Neurophysiol; 2007 Aug; 98(2):1030-41. PubMed ID: 17553943
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ethanol induces glutamate secretion by Ca2+ mobilization and ROS generation in rat hippocampal astrocytes.
    Salazar M; Pariente JA; Salido GM; González A
    Neurochem Int; 2008 May; 52(6):1061-7. PubMed ID: 18082912
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.