121 related articles for article (PubMed ID: 18997336)
1. Crystallographic characterization of the membrane-targeting domains of the Rac-specific guanine nucleotide-exchange factors Tiam1 and Tiam2.
Terawaki S; Kitano K; Hakoshima T
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Nov; 64(Pt 11):1039-42. PubMed ID: 18997336
[TBL] [Abstract][Full Text] [Related]
2. The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module.
Terawaki S; Kitano K; Mori T; Zhai Y; Higuchi Y; Itoh N; Watanabe T; Kaibuchi K; Hakoshima T
EMBO J; 2010 Jan; 29(1):236-50. PubMed ID: 19893486
[TBL] [Abstract][Full Text] [Related]
3. Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.
Chiu CY; Leng S; Martin KA; Kim E; Gorman S; Duhl DM
Genomics; 1999 Oct; 61(1):66-73. PubMed ID: 10512681
[TBL] [Abstract][Full Text] [Related]
4. The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.
Xu Z; Gakhar L; Bain FE; Spies M; Fuentes EJ
J Biol Chem; 2017 Oct; 292(43):17777-17793. PubMed ID: 28882897
[TBL] [Abstract][Full Text] [Related]
5. High-resolution structure of the Tiam1 PHn-CC-Ex domain.
Joshi M; Gakhar L; Fuentes EJ
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2013 Jul; 69(Pt 7):744-52. PubMed ID: 23832200
[TBL] [Abstract][Full Text] [Related]
6. Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam.
Robbe K; Otto-Bruc A; Chardin P; Antonny B
J Biol Chem; 2003 Feb; 278(7):4756-62. PubMed ID: 12471028
[TBL] [Abstract][Full Text] [Related]
7. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
Michiels F; Stam JC; Hordijk PL; van der Kammen RA; Ruuls-Van Stalle L; Feltkamp CA; Collard JG
J Cell Biol; 1997 Apr; 137(2):387-98. PubMed ID: 9128250
[TBL] [Abstract][Full Text] [Related]
8. Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.
Ten Klooster JP; Evers EE; Janssen L; Machesky LM; Michiels F; Hordijk P; Collard JG
Biochem J; 2006 Jul; 397(1):39-45. PubMed ID: 16599904
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Worthylake DK; Rossman KL; Sondek J
Nature; 2000 Dec; 408(6813):682-8. PubMed ID: 11130063
[TBL] [Abstract][Full Text] [Related]
10. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
Boissier P; Huynh-Do U
Cell Signal; 2014 Mar; 26(3):483-91. PubMed ID: 24308970
[TBL] [Abstract][Full Text] [Related]
11. Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain.
Stam JC; Sander EE; Michiels F; van Leeuwen FN; Kain HE; van der Kammen RA; Collard JG
J Biol Chem; 1997 Nov; 272(45):28447-54. PubMed ID: 9353304
[TBL] [Abstract][Full Text] [Related]
12. Caspase-mediated cleavage of the TIAM1 guanine nucleotide exchange factor during apoptosis.
Qi H; Juo P; Masuda-Robens J; Caloca MJ; Zhou H; Stone N; Kazanietz MG; Chou MM
Cell Growth Differ; 2001 Dec; 12(12):603-11. PubMed ID: 11751455
[TBL] [Abstract][Full Text] [Related]
13. Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands.
Crompton AM; Foley LH; Wood A; Roscoe W; Stokoe D; McCormick F; Symons M; Bollag G
J Biol Chem; 2000 Aug; 275(33):25751-9. PubMed ID: 10835422
[TBL] [Abstract][Full Text] [Related]
14. Regulation of Tiam1-Rac signalling.
Mertens AE; Roovers RC; Collard JG
FEBS Lett; 2003 Jul; 546(1):11-6. PubMed ID: 12829230
[TBL] [Abstract][Full Text] [Related]
15. Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement.
Higginbotham K; Tian Y; Gawlak G; Moldobaeva N; Shah A; Birukova AA
Cell Signal; 2014 Nov; 26(11):2306-16. PubMed ID: 25101856
[TBL] [Abstract][Full Text] [Related]
16. Mechanisms and consequences of dysregulation of the Tiam family of Rac activators in disease.
Maltas J; Reed H; Porter A; Malliri A
Biochem Soc Trans; 2020 Dec; 48(6):2703-2719. PubMed ID: 33200195
[TBL] [Abstract][Full Text] [Related]
17. CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration.
Bourguignon LY; Zhu H; Shao L; Chen YW
J Biol Chem; 2000 Jan; 275(3):1829-38. PubMed ID: 10636882
[TBL] [Abstract][Full Text] [Related]
18. Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components.
Fleming IN; Gray A; Downes CP
Biochem J; 2000 Oct; 351(Pt 1):173-82. PubMed ID: 10998360
[TBL] [Abstract][Full Text] [Related]
19. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
Adams HC; Chen R; Liu Z; Whitehead IP
Breast Cancer Res; 2010; 12(5):R69. PubMed ID: 20819206
[TBL] [Abstract][Full Text] [Related]
20. Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1).
Rajagopal S; Ji Y; Xu K; Li Y; Wicks K; Liu J; Wong KW; Herman IM; Isberg RR; Buchsbaum RJ
J Biol Chem; 2010 Jun; 285(23):18060-71. PubMed ID: 20360004
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]