BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 19003202)

  • 1. A hybrid system using both promoter activation and gene amplification for establishing exogenous protein hyper-producing cell lines.
    Dong XY; Teruya K; Katakura Y; Zhang Y; Miura T; Daimon Y; Mori T; Ohashi H; Shirahata S
    Cytotechnology; 2003 Nov; 43(1-3):11-7. PubMed ID: 19003202
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An Approach to Further Enhance the Cellular Productivity of Exogenous Protein Hyper-producing Chinese Hamster Ovary (CHO) Cells.
    Teruya K; Daimon Y; Dong XY; Katakura Y; Miura T; Ichikawa A; Fujiki T; Yamashita M; Mori T; Ohashi H; Shirahata S
    Cytotechnology; 2005 Jan; 47(1-3):29-36. PubMed ID: 19003042
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Productivity enhancement of recombinant protein in CHO cells via specific promoter activation by oncogenes.
    Katakura Y; Seto P; Miura T; Ohashi H; Teruya K; Shirahata S
    Cytotechnology; 1999 Sep; 31(1-2):103-9. PubMed ID: 19003130
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Availability of oncogene activated production system for mass production of light chain of human antibody in CHO cells.
    Miura T; Katakura Y; Seto P; Zhang Y; Teruya K; Nishimura E; Kato M; Hashizume S; Shirahata S
    Cytotechnology; 2001 Jan; 35(1):9-16. PubMed ID: 19003276
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ras amplification in BHK-21 cells produces a host cell line for further rapid establishment of recombinant protein hyper-producing cell lines.
    Teruya K; Yano T; Shirahata S; Watanabe J; Osada K; Ohashi H; Tachibana H; Kim EH; Murakami H
    Biosci Biotechnol Biochem; 1995 Feb; 59(2):341-4. PubMed ID: 7766036
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras oncogene enhances the production of a recombinant protein regulated by the cytomegalovirus promoter in BHK-21 cells.
    Yano T; Teruya K; Shirahata S; Watanabe J; Osada K; Tachibana H; Ohashi H; Kim EH; Murakami H
    Cytotechnology; 1994; 16(3):167-78. PubMed ID: 7766145
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of a highly-efficient CHO cell line generation system with engineered SV40E promoter.
    Fan L; Kadura I; Krebs LE; Larson JL; Bowden DM; Frye CC
    J Biotechnol; 2013 Dec; 168(4):652-8. PubMed ID: 23994266
    [TBL] [Abstract][Full Text] [Related]  

  • 8. E1A and ras oncogenes synergistically enhance recombinant protein production under control of the cytomegalovirus promoter in BHK-21 cells.
    Shirahata S; Watanabe J; Teruya K; Yano T; Osada K; Ohashi H; Tachibana H; Kim EH; Murakami H
    Biosci Biotechnol Biochem; 1995 Feb; 59(2):345-7. PubMed ID: 7766037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics.
    Lin PC; Chan KF; Kiess IA; Tan J; Shahreel W; Wong SY; Song Z
    MAbs; 2019 Jul; 11(5):965-976. PubMed ID: 31043114
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
    Fan L; Kadura I; Krebs LE; Hatfield CC; Shaw MM; Frye CC
    Biotechnol Bioeng; 2012 Apr; 109(4):1007-15. PubMed ID: 22068567
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficient and inducible production of human interleukin 6 in Chinese hamster ovary cells using a novel expression system.
    Zhang Y; Katakura Y; Ohashi H; Shirahata S
    Cytotechnology; 1997 Nov; 25(1-3):53-60. PubMed ID: 22358879
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Limitations to the development of recombinant human embryonic kidney 293E cells using glutamine synthetase-mediated gene amplification: Methionine sulfoximine resistance.
    Yu DY; Noh SM; Lee GM
    J Biotechnol; 2016 Aug; 231():136-140. PubMed ID: 27288593
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduced invasiveness and metastasis of Chinese hamster ovary cells transfected with human interleukin-17 gene.
    Hirahara N; Nio Y; Sasaki S; Takamura M; Iguchi C; Dong M; Yamasawa K; Itakura M; Tamura K
    Anticancer Res; 2000; 20(5A):3137-42. PubMed ID: 11062734
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A high cell density transient transfection system for therapeutic protein expression based on a CHO GS-knockout cell line: process development and product quality assessment.
    Rajendra Y; Hougland MD; Alam R; Morehead TA; Barnard GC
    Biotechnol Bioeng; 2015 May; 112(5):977-86. PubMed ID: 25502369
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methionine sulfoximine supplementation enhances productivity in GS-CHOK1SV cell lines through glutathione biosynthesis.
    Feary M; Racher AJ; Young RJ; Smales CM
    Biotechnol Prog; 2017 Jan; 33(1):17-25. PubMed ID: 27689785
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted gene therapy of the
    Hao S; Du X; Song Y; Ren M; Yang Q; Wang A; Wang Q; Zhao H; Du Z; Zhang G
    Oncol Lett; 2018 May; 15(5):6503-6512. PubMed ID: 29731853
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Derivation and characterization of cholesterol-independent non-GS NS0 cell lines for production of recombinant antibodies.
    Hartman TE; Sar N; Genereux K; Barritt DS; He Y; Burky JE; Wesson MC; Tso JY; Tsurushita N; Zhou W; Sauer PW
    Biotechnol Bioeng; 2007 Feb; 96(2):294-306. PubMed ID: 16897745
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimization of cell line development in the GS-CHO expression system using a high-throughput, single cell-based clone selection system.
    Nakamura T; Omasa T
    J Biosci Bioeng; 2015 Sep; 120(3):323-9. PubMed ID: 25792187
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1.
    Matsuyama R; Yamano N; Kawamura N; Omasa T
    J Biosci Bioeng; 2017 Mar; 123(3):382-389. PubMed ID: 27742176
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Co-amplification of EBNA-1 and PyLT through dhfr-mediated gene amplification for improving foreign protein production in transient gene expression in CHO cells.
    Lee JH; Park JH; Park SH; Kim SH; Kim JY; Min JK; Lee GM; Kim YG
    Appl Microbiol Biotechnol; 2018 Jun; 102(11):4729-4739. PubMed ID: 29654557
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.