504 related articles for article (PubMed ID: 19005070)
1. Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo.
Kim ML; Zhang B; Mills IP; Milla ME; Brunden KR; Lee VM
J Neurosci; 2008 Nov; 28(46):12052-61. PubMed ID: 19005070
[TBL] [Abstract][Full Text] [Related]
2. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
Gandhi S; Refolo LM; Sambamurti K
J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
[TBL] [Abstract][Full Text] [Related]
3. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
[TBL] [Abstract][Full Text] [Related]
4. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
[TBL] [Abstract][Full Text] [Related]
5. Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and beta-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain.
Bürger S; Noack M; Kirazov LP; Kirazov EP; Naydenov CL; Kouznetsova E; Yafai Y; Schliebs R
Int J Dev Neurosci; 2009 Oct; 27(6):517-23. PubMed ID: 19589380
[TBL] [Abstract][Full Text] [Related]
6. Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease.
Paris D; Ganey NJ; Laporte V; Patel NS; Beaulieu-Abdelahad D; Bachmeier C; March A; Ait-Ghezala G; Mullan MJ
J Neuroinflammation; 2010 Mar; 7():17. PubMed ID: 20211007
[TBL] [Abstract][Full Text] [Related]
7. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network.
Skovronsky DM; Moore DB; Milla ME; Doms RW; Lee VM
J Biol Chem; 2000 Jan; 275(4):2568-75. PubMed ID: 10644715
[TBL] [Abstract][Full Text] [Related]
8. PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases.
Pietri M; Dakowski C; Hannaoui S; Alleaume-Butaux A; Hernandez-Rapp J; Ragagnin A; Mouillet-Richard S; Haik S; Bailly Y; Peyrin JM; Launay JM; Kellermann O; Schneider B
Nat Med; 2013 Sep; 19(9):1124-31. PubMed ID: 23955714
[TBL] [Abstract][Full Text] [Related]
9. AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice.
Eketjäll S; Janson J; Jeppsson F; Svanhagen A; Kolmodin K; Gustavsson S; Radesäter AC; Eliason K; Briem S; Appelkvist P; Niva C; Berg AL; Karlström S; Swahn BM; Fälting J
J Neurosci; 2013 Jun; 33(24):10075-84. PubMed ID: 23761903
[TBL] [Abstract][Full Text] [Related]
10. BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.
Roberds SL; Anderson J; Basi G; Bienkowski MJ; Branstetter DG; Chen KS; Freedman SB; Frigon NL; Games D; Hu K; Johnson-Wood K; Kappenman KE; Kawabe TT; Kola I; Kuehn R; Lee M; Liu W; Motter R; Nichols NF; Power M; Robertson DW; Schenk D; Schoor M; Shopp GM; Shuck ME; Sinha S; Svensson KA; Tatsuno G; Tintrup H; Wijsman J; Wright S; McConlogue L
Hum Mol Genet; 2001 Jun; 10(12):1317-24. PubMed ID: 11406613
[TBL] [Abstract][Full Text] [Related]
11. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
[TBL] [Abstract][Full Text] [Related]
12. CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.
Dobrowolska JA; Michener MS; Wu G; Patterson BW; Chott R; Ovod V; Pyatkivskyy Y; Wildsmith KR; Kasten T; Mathers P; Dancho M; Lennox C; Smith BE; Gilberto D; McLoughlin D; Holder DJ; Stamford AW; Yarasheski KE; Kennedy ME; Savage MJ; Bateman RJ
J Neurosci; 2014 Jun; 34(24):8336-46. PubMed ID: 24920637
[TBL] [Abstract][Full Text] [Related]
13. Icariin decreases the expression of APP and BACE-1 and reduces the β-amyloid burden in an APP transgenic mouse model of Alzheimer's disease.
Zhang L; Shen C; Chu J; Zhang R; Li Y; Li L
Int J Biol Sci; 2014; 10(2):181-91. PubMed ID: 24550686
[TBL] [Abstract][Full Text] [Related]
14. Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques.
Skovronsky DM; Fath S; Lee VM; Milla ME
J Neurobiol; 2001 Oct; 49(1):40-6. PubMed ID: 11536196
[TBL] [Abstract][Full Text] [Related]
15. Dynamin 1 regulates amyloid generation through modulation of BACE-1.
Zhu L; Su M; Lucast L; Liu L; Netzer WJ; Gandy SE; Cai D
PLoS One; 2012; 7(9):e45033. PubMed ID: 23024787
[TBL] [Abstract][Full Text] [Related]
16. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
Rockenstein E; Torrance M; Mante M; Adame A; Paulino A; Rose JB; Crews L; Moessler H; Masliah E
J Neurosci Res; 2006 May; 83(7):1252-61. PubMed ID: 16511867
[TBL] [Abstract][Full Text] [Related]
17. BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo.
Lee EB; Zhang B; Liu K; Greenbaum EA; Doms RW; Trojanowski JQ; Lee VM
J Cell Biol; 2005 Jan; 168(2):291-302. PubMed ID: 15642747
[TBL] [Abstract][Full Text] [Related]
18. Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
Yamamoto M; Kiyota T; Horiba M; Buescher JL; Walsh SM; Gendelman HE; Ikezu T
Am J Pathol; 2007 Feb; 170(2):680-92. PubMed ID: 17255335
[TBL] [Abstract][Full Text] [Related]
19. Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology.
Rossner S; Apelt J; Schliebs R; Perez-Polo JR; Bigl V
J Neurosci Res; 2001 Jun; 64(5):437-46. PubMed ID: 11391698
[TBL] [Abstract][Full Text] [Related]
20. A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.
Neumann U; Rueeger H; Machauer R; Veenstra SJ; Lueoend RM; Tintelnot-Blomley M; Laue G; Beltz K; Vogg B; Schmid P; Frieauff W; Shimshek DR; Staufenbiel M; Jacobson LH
Mol Neurodegener; 2015 Sep; 10():44. PubMed ID: 26336937
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
