These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Wood JG; Rogina B; Lavu S; Howitz K; Helfand SL; Tatar M; Sinclair D Nature; 2004 Aug; 430(7000):686-9. PubMed ID: 15254550 [TBL] [Abstract][Full Text] [Related]
4. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Burnett C; Valentini S; Cabreiro F; Goss M; Somogyvári M; Piper MD; Hoddinott M; Sutphin GL; Leko V; McElwee JJ; Vazquez-Manrique RP; Orfila AM; Ackerman D; Au C; Vinti G; Riesen M; Howard K; Neri C; Bedalov A; Kaeberlein M; Soti C; Partridge L; Gems D Nature; 2011 Sep; 477(7365):482-5. PubMed ID: 21938067 [TBL] [Abstract][Full Text] [Related]
5. Small molecules that regulate lifespan: evidence for xenohormesis. Lamming DW; Wood JG; Sinclair DA Mol Microbiol; 2004 Aug; 53(4):1003-9. PubMed ID: 15306006 [TBL] [Abstract][Full Text] [Related]
6. SIRT1 stimulation by polyphenols is affected by their stability and metabolism. de Boer VC; de Goffau MC; Arts IC; Hollman PC; Keijer J Mech Ageing Dev; 2006 Jul; 127(7):618-27. PubMed ID: 16603228 [TBL] [Abstract][Full Text] [Related]
7. Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. Tsuchiya M; Dang N; Kerr EO; Hu D; Steffen KK; Oakes JA; Kennedy BK; Kaeberlein M Aging Cell; 2006 Dec; 5(6):505-14. PubMed ID: 17129213 [TBL] [Abstract][Full Text] [Related]
8. Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins. Smith DL; McClure JM; Matecic M; Smith JS Aging Cell; 2007 Oct; 6(5):649-62. PubMed ID: 17711561 [TBL] [Abstract][Full Text] [Related]
9. Sirtuins: the 'magnificent seven', function, metabolism and longevity. Dali-Youcef N; Lagouge M; Froelich S; Koehl C; Schoonjans K; Auwerx J Ann Med; 2007; 39(5):335-45. PubMed ID: 17701476 [TBL] [Abstract][Full Text] [Related]
10. Ageing: a toast to long life. Finkel T Nature; 2003 Sep; 425(6954):132-3. PubMed ID: 12968159 [No Abstract] [Full Text] [Related]
11. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Anderson RM; Bitterman KJ; Wood JG; Medvedik O; Sinclair DA Nature; 2003 May; 423(6936):181-5. PubMed ID: 12736687 [TBL] [Abstract][Full Text] [Related]
12. SIR2: a potential target for calorie restriction mimetics. Chen D; Guarente L Trends Mol Med; 2007 Feb; 13(2):64-71. PubMed ID: 17207661 [TBL] [Abstract][Full Text] [Related]
13. Longevity research. In vino vitalis? Compounds activate life-extending genes. Hall SS Science; 2003 Aug; 301(5637):1165. PubMed ID: 12947168 [No Abstract] [Full Text] [Related]
14. dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster. Bauer JH; Morris SN; Chang C; Flatt T; Wood JG; Helfand SL Aging (Albany NY); 2009 Jan; 1(1):38-48. PubMed ID: 19851477 [TBL] [Abstract][Full Text] [Related]
15. HST2 mediates SIR2-independent life-span extension by calorie restriction. Lamming DW; Latorre-Esteves M; Medvedik O; Wong SN; Tsang FA; Wang C; Lin SJ; Sinclair DA Science; 2005 Sep; 309(5742):1861-4. PubMed ID: 16051752 [TBL] [Abstract][Full Text] [Related]
16. Sir2 and calorie restriction in yeast: a skeptical perspective. Kaeberlein M; Powers RW Ageing Res Rev; 2007 Aug; 6(2):128-40. PubMed ID: 17512264 [TBL] [Abstract][Full Text] [Related]
17. Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Kaeberlein M; Steffen KK; Hu D; Dang N; Kerr EO; Tsuchiya M; Fields S; Kennedy BK Science; 2006 Jun; 312(5778):1312; author reply 1312. PubMed ID: 16741098 [TBL] [Abstract][Full Text] [Related]
18. A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis. Imai S Pharmacol Res; 2010 Jul; 62(1):42-7. PubMed ID: 20085812 [TBL] [Abstract][Full Text] [Related]
19. Sirtuins in aging and disease. Guarente L Cold Spring Harb Symp Quant Biol; 2007; 72():483-8. PubMed ID: 18419308 [TBL] [Abstract][Full Text] [Related]