184 related articles for article (PubMed ID: 19013076)
1. Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads.
Kotthaus J; Schade D; Muschick N; Beitz E; Clement B
Bioorg Med Chem; 2008 Dec; 16(24):10205-9. PubMed ID: 19013076
[TBL] [Abstract][Full Text] [Related]
2. S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase.
Leiper J; Murray-Rust J; McDonald N; Vallance P
Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13527-32. PubMed ID: 12370443
[TBL] [Abstract][Full Text] [Related]
3. Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons.
Selley ML
J Neurosci Res; 2004 Jul; 77(1):90-3. PubMed ID: 15197741
[TBL] [Abstract][Full Text] [Related]
4. Designing modulators of dimethylarginine dimethylaminohydrolase (DDAH): a focus on selectivity over arginase.
Kotthaus J; Schade D; Kotthaus J; Clement B
J Enzyme Inhib Med Chem; 2012 Feb; 27(1):24-8. PubMed ID: 21740101
[TBL] [Abstract][Full Text] [Related]
5. Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors.
Frey D; Braun O; Briand C; Vasák M; Grütter MG
Structure; 2006 May; 14(5):901-11. PubMed ID: 16698551
[TBL] [Abstract][Full Text] [Related]
6. Characterization of a transient covalent adduct formed during dimethylarginine dimethylaminohydrolase catalysis.
Stone EM; Person MD; Costello NJ; Fast W
Biochemistry; 2005 May; 44(18):7069-78. PubMed ID: 15865451
[TBL] [Abstract][Full Text] [Related]
7. Alternative nitric oxide-producing substrates for NO synthases.
Mansuy D; Boucher JL
Free Radic Biol Med; 2004 Oct; 37(8):1105-21. PubMed ID: 15451052
[TBL] [Abstract][Full Text] [Related]
8. Pharmacological activation of dimethylarginine dimethylaminohydrolase (DDAH) activity by inorganic nitrate and DDAH inhibition by N
Bollenbach A; Tsikas D
Amino Acids; 2019 Mar; 51(3):483-494. PubMed ID: 30536052
[TBL] [Abstract][Full Text] [Related]
9. N(delta)-Methylated L-arginine derivatives and their effects on the nitric oxide generating system.
Kotthaus J; Schade D; Töpker-Lehmann K; Beitz E; Clement B
Bioorg Med Chem; 2008 Mar; 16(5):2305-12. PubMed ID: 18083522
[TBL] [Abstract][Full Text] [Related]
10. Substrate-assisted cysteine deprotonation in the mechanism of dimethylargininase (DDAH) from Pseudomonas aeruginosa.
Stone EM; Costello AL; Tierney DL; Fast W
Biochemistry; 2006 May; 45(17):5618-30. PubMed ID: 16634643
[TBL] [Abstract][Full Text] [Related]
11. The prominent role of the liver in the elimination of asymmetric dimethylarginine (ADMA) and the consequences of impaired hepatic function.
Richir MC; Bouwman RH; Teerlink T; Siroen MP; de Vries TP; van Leeuwen PA
JPEN J Parenter Enteral Nutr; 2008; 32(6):613-21. PubMed ID: 18974239
[TBL] [Abstract][Full Text] [Related]
12. Dimethylarginine-dimethylaminohydrolase-2 (DDAH-2) does not metabolize methylarginines.
Altmann KS; Havemeyer A; Beitz E; Clement B
Chembiochem; 2012 Nov; 13(17):2599-604. PubMed ID: 23125090
[TBL] [Abstract][Full Text] [Related]
13. Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase.
Murray-Rust J; Leiper J; McAlister M; Phelan J; Tilley S; Santa Maria J; Vallance P; McDonald N
Nat Struct Biol; 2001 Aug; 8(8):679-83. PubMed ID: 11473257
[TBL] [Abstract][Full Text] [Related]
14. Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Wang Y; Monzingo AF; Hu S; Schaller TH; Robertus JD; Fast W
Biochemistry; 2009 Sep; 48(36):8624-35. PubMed ID: 19663506
[TBL] [Abstract][Full Text] [Related]
15. GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans.
Chobanyan K; Thum T; Suchy MT; Zhu B; Mitschke A; Gutzki FM; Beckmann B; Stichtenoth DO; Tsikas D
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Oct; 858(1-2):32-41. PubMed ID: 17825631
[TBL] [Abstract][Full Text] [Related]
16. Accumulated endogenous nitric oxide synthase inhibitors in inhibiting urethral relaxation following estrogen supplementation in ovariectomized rabbits.
Okuno T; Masuda H; Tsujii T; Kihara K; Yamauchi Y; Azuma H
J Urol; 2004 Jul; 172(1):360-4. PubMed ID: 15201811
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) and arginine deiminase (ADI) by pentafluorophenyl (PFP) sulfonates.
Vallance P; Bush HD; Mok BJ; Hurtado-Guerrero R; Gill H; Rossiter S; Wilden JD; Caddick S
Chem Commun (Camb); 2005 Nov; (44):5563-5. PubMed ID: 16358064
[TBL] [Abstract][Full Text] [Related]
18. Arginine analogues incorporating carboxylate bioisosteric functions are micromolar inhibitors of human recombinant DDAH-1.
Tommasi S; Zanato C; Lewis BC; Nair PC; Dall'Angelo S; Zanda M; Mangoni AA
Org Biomol Chem; 2015 Dec; 13(46):11315-30. PubMed ID: 26420019
[TBL] [Abstract][Full Text] [Related]
19. Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO.
Lefèvre-Groboillot D; Boucher JL; Stuehr DJ; Mansuy D
FEBS J; 2005 Jun; 272(12):3172-83. PubMed ID: 15955074
[TBL] [Abstract][Full Text] [Related]
20. The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis.
Janssen W; Pullamsetti SS; Cooke J; Weissmann N; Guenther A; Schermuly RT
J Pathol; 2013 Jan; 229(2):242-9. PubMed ID: 23097221
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]