144 related articles for article (PubMed ID: 19015228)
1. Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).
Conseil G; Rothnie AJ; Deeley RG; Cole SP
Mol Pharmacol; 2009 Feb; 75(2):397-406. PubMed ID: 19015228
[TBL] [Abstract][Full Text] [Related]
2. Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).
Conseil G; Deeley RG; Cole SP
J Biol Chem; 2006 Jan; 281(1):43-50. PubMed ID: 16230346
[TBL] [Abstract][Full Text] [Related]
3. Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter.
Situ D; Haimeur A; Conseil G; Sparks KE; Zhang D; Deeley RG; Cole SP
J Biol Chem; 2004 Sep; 279(37):38871-80. PubMed ID: 15208328
[TBL] [Abstract][Full Text] [Related]
4. Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.
Létourneau IJ; Slot AJ; Deeley RG; Cole SP
Drug Metab Dispos; 2007 Aug; 35(8):1372-9. PubMed ID: 17494643
[TBL] [Abstract][Full Text] [Related]
5. Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.
Koike K; Conseil G; Leslie EM; Deeley RG; Cole SP
J Biol Chem; 2004 Mar; 279(13):12325-36. PubMed ID: 14722114
[TBL] [Abstract][Full Text] [Related]
6. Expression and function of human MRP1 (ABCC1) is dependent on amino acids in cytoplasmic loop 5 and its interface with nucleotide binding domain 2.
Iram SH; Cole SP
J Biol Chem; 2011 Mar; 286(9):7202-13. PubMed ID: 21177244
[TBL] [Abstract][Full Text] [Related]
7. Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).
Haimeur A; Conseil G; Deeley RG; Cole SP
Mol Pharmacol; 2004 Jun; 65(6):1375-85. PubMed ID: 15155831
[TBL] [Abstract][Full Text] [Related]
8. Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.
Létourneau IJ; Nakajima A; Deeley RG; Cole SP
Biochem Pharmacol; 2008 Apr; 75(8):1659-69. PubMed ID: 18336795
[TBL] [Abstract][Full Text] [Related]
9. Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).
Leslie EM; Létourneau IJ; Deeley RG; Cole SP
Biochemistry; 2003 May; 42(18):5214-24. PubMed ID: 12731862
[TBL] [Abstract][Full Text] [Related]
10. An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1).
Weigl KE; Conseil G; Rothnie AJ; Arama M; Tsfadia Y; Cole SPC
Mol Pharmacol; 2018 Sep; 94(3):1069-1078. PubMed ID: 29976562
[TBL] [Abstract][Full Text] [Related]
11. Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter.
Iram SH; Cole SP
Biochim Biophys Acta; 2014 Mar; 1838(3):756-65. PubMed ID: 24231430
[TBL] [Abstract][Full Text] [Related]
12. Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state.
Zhang DW; Gu HM; Situ D; Haimeur A; Cole SP; Deeley RG
J Biol Chem; 2003 Nov; 278(46):46052-63. PubMed ID: 12954620
[TBL] [Abstract][Full Text] [Related]
13. Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).
Payen LF; Gao M; Westlake CJ; Cole SP; Deeley RG
J Biol Chem; 2003 Oct; 278(40):38537-47. PubMed ID: 12882957
[TBL] [Abstract][Full Text] [Related]
14. Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1.
Zhang DW; Nunoya K; Vasa M; Gu HM; Theis A; Cole SP; Deeley RG
Biochemistry; 2004 Jul; 43(29):9413-25. PubMed ID: 15260484
[TBL] [Abstract][Full Text] [Related]
15. The First Cytoplasmic Loop in the Core Structure of the ABCC1 (Multidrug Resistance Protein 1; MRP1) Transporter Contains Multiple Amino Acids Essential for Its Expression.
Conseil G; Cole SPC
Int J Mol Sci; 2021 Sep; 22(18):. PubMed ID: 34575890
[TBL] [Abstract][Full Text] [Related]
16. Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity.
Haimeur A; Deeley RG; Cole SP
J Biol Chem; 2002 Nov; 277(44):41326-33. PubMed ID: 12186871
[TBL] [Abstract][Full Text] [Related]
17. Conserved amino acids in the region connecting membrane spanning domain 1 to nucleotide binding domain 1 are essential for expression of the MRP1 (ABCC1) transporter.
Smith EE; Conseil G; Cole SPC
PLoS One; 2021; 16(2):e0246727. PubMed ID: 33571281
[TBL] [Abstract][Full Text] [Related]
18. Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.
Leslie EM; Mao Q; Oleschuk CJ; Deeley RG; Cole SP
Mol Pharmacol; 2001 May; 59(5):1171-80. PubMed ID: 11306701
[TBL] [Abstract][Full Text] [Related]
19. Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).
Létourneau IJ; Deeley RG; Cole SP
Pharmacogenet Genomics; 2005 Sep; 15(9):647-57. PubMed ID: 16041243
[TBL] [Abstract][Full Text] [Related]
20. Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1).
Iram SH; Cole SP
J Biol Chem; 2012 Mar; 287(10):7543-55. PubMed ID: 22232552
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
