295 related articles for article (PubMed ID: 19022182)
1. Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes.
Scott JW; van Denderen BJ; Jorgensen SB; Honeyman JE; Steinberg GR; Oakhill JS; Iseli TJ; Koay A; Gooley PR; Stapleton D; Kemp BE
Chem Biol; 2008 Nov; 15(11):1220-30. PubMed ID: 19022182
[TBL] [Abstract][Full Text] [Related]
2. Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators.
Rajamohan F; Reyes AR; Frisbie RK; Hoth LR; Sahasrabudhe P; Magyar R; Landro JA; Withka JM; Caspers NL; Calabrese MF; Ward J; Kurumbail RG
Biochem J; 2016 Mar; 473(5):581-92. PubMed ID: 26635351
[TBL] [Abstract][Full Text] [Related]
3. Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.
Scott JW; Ling N; Issa SM; Dite TA; O'Brien MT; Chen ZP; Galic S; Langendorf CG; Steinberg GR; Kemp BE; Oakhill JS
Chem Biol; 2014 May; 21(5):619-27. PubMed ID: 24746562
[TBL] [Abstract][Full Text] [Related]
4. Escherichia coli expression, purification and characterization of functional full-length recombinant alpha2beta2gamma3 heterotrimeric complex of human AMP-activated protein kinase.
Rajamohan F; Harris MS; Frisbie RK; Hoth LR; Geoghegan KF; Valentine JJ; Reyes AR; Landro JA; Qiu X; Kurumbail RG
Protein Expr Purif; 2010 Oct; 73(2):189-97. PubMed ID: 20451617
[TBL] [Abstract][Full Text] [Related]
5. Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662.
Ducommun S; Ford RJ; Bultot L; Deak M; Bertrand L; Kemp BE; Steinberg GR; Sakamoto K
Am J Physiol Endocrinol Metab; 2014 Mar; 306(6):E688-96. PubMed ID: 24425763
[TBL] [Abstract][Full Text] [Related]
6. A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake.
Timmermans AD; Balteau M; Gélinas R; Renguet E; Ginion A; de Meester C; Sakamoto K; Balligand JL; Bontemps F; Vanoverschelde JL; Horman S; Beauloye C; Bertrand L
Am J Physiol Heart Circ Physiol; 2014 Jun; 306(12):H1619-30. PubMed ID: 24748590
[TBL] [Abstract][Full Text] [Related]
7. Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family.
Sanders MJ; Ali ZS; Hegarty BD; Heath R; Snowden MA; Carling D
J Biol Chem; 2007 Nov; 282(45):32539-48. PubMed ID: 17728241
[TBL] [Abstract][Full Text] [Related]
8. ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.
Scott JW; Oakhill JS; Ling NX; Langendorf CG; Foitzik RC; Kemp BE; Issinger OG
Biochem Biophys Res Commun; 2014 Jan; 443(2):435-40. PubMed ID: 24332941
[TBL] [Abstract][Full Text] [Related]
9. The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.
Dite TA; Ling NXY; Scott JW; Hoque A; Galic S; Parker BL; Ngoei KRW; Langendorf CG; O'Brien MT; Kundu M; Viollet B; Steinberg GR; Sakamoto K; Kemp BE; Oakhill JS
Nat Commun; 2017 Sep; 8(1):571. PubMed ID: 28924239
[TBL] [Abstract][Full Text] [Related]
10. Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms.
Pinkosky SL; Scott JW; Desjardins EM; Smith BK; Day EA; Ford RJ; Langendorf CG; Ling NXY; Nero TL; Loh K; Galic S; Hoque A; Smiles WJ; Ngoei KRW; Parker MW; Yan Y; Melcher K; Kemp BE; Oakhill JS; Steinberg GR
Nat Metab; 2020 Sep; 2(9):873-881. PubMed ID: 32719536
[TBL] [Abstract][Full Text] [Related]
11. Phosphorylation of AMPK by upstream kinases is required for activity in mammalian cells.
Willows R; Sanders MJ; Xiao B; Patel BR; Martin SR; Read J; Wilson JR; Hubbard J; Gamblin SJ; Carling D
Biochem J; 2017 Aug; 474(17):3059-3073. PubMed ID: 28694351
[TBL] [Abstract][Full Text] [Related]
12. A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle.
Treebak JT; Birk JB; Hansen BF; Olsen GS; Wojtaszewski JF
Am J Physiol Cell Physiol; 2009 Oct; 297(4):C1041-52. PubMed ID: 19657063
[TBL] [Abstract][Full Text] [Related]
13. β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).
Oakhill JS; Chen ZP; Scott JW; Steel R; Castelli LA; Ling N; Macaulay SL; Kemp BE
Proc Natl Acad Sci U S A; 2010 Nov; 107(45):19237-41. PubMed ID: 20974912
[TBL] [Abstract][Full Text] [Related]
14. AMPK is a direct adenylate charge-regulated protein kinase.
Oakhill JS; Steel R; Chen ZP; Scott JW; Ling N; Tam S; Kemp BE
Science; 2011 Jun; 332(6036):1433-5. PubMed ID: 21680840
[TBL] [Abstract][Full Text] [Related]
15. Structure and function of AMP-activated protein kinase.
Oakhill JS; Scott JW; Kemp BE
Acta Physiol (Oxf); 2009 May; 196(1):3-14. PubMed ID: 19245650
[TBL] [Abstract][Full Text] [Related]
16. A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase.
Strembitska A; Mancini SJ; Gamwell JM; Palmer TM; Baillie GS; Salt IP
Int J Mol Sci; 2018 Dec; 19(12):. PubMed ID: 30563079
[TBL] [Abstract][Full Text] [Related]
17. Niclosamide activates the AMP-activated protein kinase complex containing the β2 subunit independently of AMP.
Suzuki T; Kojima M; Matsumoto Y; Kobayashi KI; Inoue J; Yamamoto Y
Biochem Biophys Res Commun; 2020 Dec; 533(4):758-763. PubMed ID: 32993962
[TBL] [Abstract][Full Text] [Related]
18. AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.
Bultot L; Guigas B; Von Wilamowitz-Moellendorff A; Maisin L; Vertommen D; Hussain N; Beullens M; Guinovart JJ; Foretz M; Viollet B; Sakamoto K; Hue L; Rider MH
Biochem J; 2012 Apr; 443(1):193-203. PubMed ID: 22233421
[TBL] [Abstract][Full Text] [Related]
19. Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice.
Li YY; Yu LF; Zhang LN; Qiu BY; Su MB; Wu F; Chen DK; Pang T; Gu M; Zhang W; Ma WP; Jiang HW; Li JY; Nan FJ; Li J
Toxicol Appl Pharmacol; 2013 Dec; 273(2):325-34. PubMed ID: 24055643
[TBL] [Abstract][Full Text] [Related]
20. A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.
Lai YC; Kviklyte S; Vertommen D; Lantier L; Foretz M; Viollet B; Hallén S; Rider MH
Biochem J; 2014 Jun; 460(3):363-75. PubMed ID: 24665903
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
