BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 19023113)

  • 1. Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.
    Longo NS; Lugar PL; Yavuz S; Zhang W; Krijger PH; Russ DE; Jima DD; Dave SS; Grammer AC; Lipsky PE
    Blood; 2009 Apr; 113(16):3706-15. PubMed ID: 19023113
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of somatic hypermutations in the IgM switch region in human B cells.
    Horiuchi K; Imai K; Mitsui-Sekinaka K; Yeh TW; Ochs HD; Durandy A; Nonoyama S
    J Allergy Clin Immunol; 2014 Aug; 134(2):411-9. PubMed ID: 24836470
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase.
    Longo NS; Satorius CL; Plebani A; Durandy A; Lipsky PE
    J Immunol; 2008 Jul; 181(2):1299-306. PubMed ID: 18606684
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination.
    Xu Z; Pone EJ; Al-Qahtani A; Park SR; Zan H; Casali P
    Crit Rev Immunol; 2007; 27(4):367-97. PubMed ID: 18197815
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of CD40-CD40 ligand (CD154) interactions in immunoglobulin light chain repertoire generation and somatic mutation.
    Monson NL; Foster SJ; Brezinschek HP; Brezinschek RI; Dörner T; Lipsky PE
    Clin Immunol; 2001 Jul; 100(1):71-81. PubMed ID: 11414747
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome.
    Kuraoka M; Liao D; Yang K; Allgood SD; Levesque MC; Kelsoe G; Ueda Y
    J Immunol; 2009 Sep; 183(5):3237-48. PubMed ID: 19667096
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Somatic hypermutation of VkappaJkappa rearrangements: targeting of RGYW motifs on both DNA strands and preferential selection of mutated codons within RGYW motifs.
    Foster SJ; Dörner T; Lipsky PE
    Eur J Immunol; 1999 Dec; 29(12):4011-21. PubMed ID: 10602011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development.
    Marr S; Morales H; Bottaro A; Cooper M; Flajnik M; Robert J
    J Immunol; 2007 Nov; 179(10):6783-9. PubMed ID: 17982068
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.
    Hubbard N; Hagin D; Sommer K; Song Y; Khan I; Clough C; Ochs HD; Rawlings DJ; Scharenberg AM; Torgerson TR
    Blood; 2016 May; 127(21):2513-22. PubMed ID: 26903548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization.
    Yewdell WT; Kim Y; Chowdhury P; Lau CM; Smolkin RM; Belcheva KT; Fernandez KC; Cols M; Yen WF; Vaidyanathan B; Angeletti D; McDermott AB; Yewdell JW; Sun JC; Chaudhuri J
    Immunity; 2020 Nov; 53(5):952-970.e11. PubMed ID: 33098766
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human CD19 and CD40L deficiencies impair antibody selection and differentially affect somatic hypermutation.
    van Zelm MC; Bartol SJ; Driessen GJ; Mascart F; Reisli I; Franco JL; Wolska-Kusnierz B; Kanegane H; Boon L; van Dongen JJ; van der Burg M
    J Allergy Clin Immunol; 2014 Jul; 134(1):135-44. PubMed ID: 24418477
    [TBL] [Abstract][Full Text] [Related]  

  • 12. B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil.
    Kavli B; Andersen S; Otterlei M; Liabakk NB; Imai K; Fischer A; Durandy A; Krokan HE; Slupphaug G
    J Exp Med; 2005 Jun; 201(12):2011-21. PubMed ID: 15967827
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells.
    Komori A; Xu Z; Wu X; Zan H; Casali P
    Mol Immunol; 2006 Apr; 43(11):1817-26. PubMed ID: 16412510
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatic hypermutation targeting to intrinsic hotspots of immunoglobulin genes in follicular lymphoma and multiple myeloma.
    Belessi C; Stamatopoulos K; Stavroyianni N; Zoi K; Papadaki T; Kosmas C
    Leukemia; 2001 Nov; 15(11):1772-8. PubMed ID: 11681420
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular analysis of a large cohort of patients with the hyper immunoglobulin M (IgM) syndrome.
    Lee WI; Torgerson TR; Schumacher MJ; Yel L; Zhu Q; Ochs HD
    Blood; 2005 Mar; 105(5):1881-90. PubMed ID: 15358621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas.
    Greeve J; Philipsen A; Krause K; Klapper W; Heidorn K; Castle BE; Janda J; Marcu KB; Parwaresch R
    Blood; 2003 May; 101(9):3574-80. PubMed ID: 12511417
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas.
    Martin A; Bardwell PD; Woo CJ; Fan M; Shulman MJ; Scharff MD
    Nature; 2002 Feb; 415(6873):802-6. PubMed ID: 11823785
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process.
    Rogozin IB; Diaz M
    J Immunol; 2004 Mar; 172(6):3382-4. PubMed ID: 15004135
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line.
    Chezar I; Lobel-Lavi L; Steinitz M; Laskov R
    Mol Immunol; 2008 Nov; 46(1):80-90. PubMed ID: 18718665
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of 6912 unselected somatic hypermutations in human VDJ rearrangements reveals lack of strand specificity and correlation between phase II substitution rates and distance to the nearest 3' activation-induced cytidine deaminase target.
    Ohm-Laursen L; Barington T
    J Immunol; 2007 Apr; 178(7):4322-34. PubMed ID: 17371989
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.